Results 21 to 30 of about 53,901 (244)

Effect of Differences in the CLSI and EUCAST Criteria on the Interpretation of Enterobacteriaceae Sensitivity to Carbapenems

open access: yesАнтибиотики и Химиотерапия, 2021
Relevance: The two systems for determining the susceptibility of bacteria to antimicrobial drugs, CLSI and EUCAST, are recommended for use in the global system of epidemiological surveillance of antimicrobial resistance of the World Health Organization ...
L. A. Kornoukhova   +3 more
doaj   +1 more source

Biapenem: Clinical and Microbiological Characteristics and the Place of The New Carbapenem In The Treatment of Severe Infections In The Hospital. Clinical Pharmacologists' Point of View

open access: yesАнтибиотики и Химиотерапия, 2022
A new carbapenem antibiotic — biapenem — previously used only in Japan and Southeast Asia, was registered in Russia in 2021. The article analyzes the antimicrobial, pharmacokinetic, and clinical characteristics of biapenem in detail, provides ...
S. V. YAKOVLEV, M. P. SUVOROVA
doaj   +1 more source

Carbapenem-Resistant Enterobacteriaceae [PDF]

open access: yesClinics in Laboratory Medicine, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a major threat. Commonly used antibiotics are generally inactive against CRE. Therefore, timely detection of CRE is of paramount importance. Among CRE, those producing carbapenem-hydrolyzing β-lactamase enzymes (carbapenemase-producing Enterobacteriaceae) are particularly of concern because ...
Alina, Iovleva, Yohei, Doi
openaire   +2 more sources

The Impact of Acinetobacter baumannii Infections in COVID-19 Patients Admitted in Hospital Intensive Care Units

open access: yesBiology and Life Sciences Forum, 2023
Since the end of 2019, the Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, affecting people worldwide.
Corneliu Ovidiu Vrancianu   +6 more
doaj   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

New developments in carbapenems [PDF]

open access: yesClinical Microbiology and Infection, 2008
Antibiotic resistance among Gram-negative pathogens in hospitals is a growing threat to patients and is driving the increased use of carbapenems. Carbapenems are potent members of the beta-lactam family of antibiotics, with a history of safety and efficacy for serious infections that exceeds 20 years. Original and review articles were identified from a
Kattan, J.N.   +2 more
openaire   +2 more sources

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

open access: yesAngewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray   +4 more
wiley   +2 more sources

THE CORRESPONDENCE OF THE CARBAPENEMASE GENOTYPE AND PHENOTYPIC ANTIMICROBIAL PROFILES OF PSEUDOMONAS AERUGINOSA

open access: yesПроблеми екології та медицини, 2023
The aim of the study was to determine the correspondence between the carbapenemase genotype and the phenotypic antimicrobial profiles of P. aeruginosa. Materials and methods. The study included 51 clinical isolates of P.
N. Bahniuk   +6 more
doaj   +1 more source

The correlation between various phenotypic MDR patterns and the carbapenems resistance genes.

open access: yes, 2022
The correlation between various phenotypic MDR patterns and the carbapenems resistance genes.
Fateme Jahangirimehr (12524820)   +2 more
core   +1 more source

Potentiation of antimicrobial activity of colistin with antibiotics of different groups against multidrug- and extensively drug-resistant strains of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2020
Objective. To reveal antibiotics being capable of potentiating the antimicrobial activity of colistin against multidrug- and extensively drug-resistant strains of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa. Materials and
Tapalskiy D.V.   +3 more
doaj   +1 more source

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