Results 21 to 30 of about 40,327 (214)

Potentiation of antimicrobial activity of colistin with antibiotics of different groups against multidrug- and extensively drug-resistant strains of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2020
Objective. To reveal antibiotics being capable of potentiating the antimicrobial activity of colistin against multidrug- and extensively drug-resistant strains of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa. Materials and
Tapalskiy D.V., Petrovskaya T.A., Kozlova A.I., Edelstein M.V.   +3 more
doaj   +1 more source

Carbapenem-Resistant Enterobacteriaceae [PDF]

Clinics in Laboratory Medicine, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a major threat. Commonly used antibiotics are generally inactive against CRE. Therefore, timely detection of CRE is of paramount importance. Among CRE, those producing carbapenem-hydrolyzing β-lactamase enzymes (carbapenemase-producing Enterobacteriaceae) are particularly of concern because ...
Alina, Iovleva, Yohei, Doi
openaire   +2 more sources

Emergence and transmission of Carbapenem-resistant Enterobacteriaceae blaNDM-5 gene in healthy pigs in Baise, Guangxi, China: a discovery

Frontiers in Veterinary Science
A total of 366 tonsillar tissue samples were collected from healthy free-range pigs owned by farmers across 12 districts in Baise City, Guangxi, China.
Yuan-Yuan Dai, Yuan-Yuan Dai, Yuan-Yuan Dai, Yuan-Yuan Dai, Wen-Fei Wei, Wen-Fei Wei, Xue-zhen Li, Chao-Yuan Yuan, Li-Juan Zhao, Yan-Qiang Huang, Yan-Qiang Huang, Yan-Qiang Huang, Ming Hao, Ying Deng, Ying Deng, Ying Deng, Ying Deng, Yuan-Ji Teng, Yuan-Ji Teng, Yuan-Ji Teng, Yuan-Ji Teng, Xue-Li Yi, Xue-Li Yi, Xue-Li Yi, Xue-Li Yi   +24 more
doaj   +1 more source

Retrospective Analysis of Bacterial Cultures Sampled in German Chicken-Fattening Farms During the Years 2011–2012 Revealed Additional VIM-1 Carbapenemase-Producing Escherichia coli and a Serologically Rough Salmonella enterica Serovar Infantis

Frontiers in Microbiology, 2018
Carbapenems are last-resort antibiotics used in human medicine. The increased detection of carbapenem-resistant Enterobacteriaceae (CRE) is therefore worrying.
Nicole Roschanski, Jennie Fischer, Linda Falgenhauer, Michael Pietsch, Sebastian Guenther, Lothar Kreienbrock, Trinad Chakraborty, Yvonne Pfeifer, Beatriz Guerra, Uwe H. Roesler   +9 more
doaj   +1 more source

Molecular Characterization of KPC-2-Producing Enterobacter cloacae Complex Isolates from Cali, Colombia

Antibiotics, 2021
The Enterobacter cloacae complex is an emerging opportunistic pathogen whose increased resistance to carbapenems is considered a public health problem. This is due to the loss of efficacy of beta-lactam antibiotics, which are used as the first treatment ...
Aura Falco, Daniela Guerrero, Isabella García, Adriana Correa, Sandra Rivera, María Beatriz Olaya, Carlos Aranaga   +6 more
doaj   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

Rapid Multiplex Antimicrobial Resistance Profiling and Bacterial Identification by LAP‐MALDI Mass Spectrometry Biotyping

Advanced Science, EarlyView.
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair, Shabnam Iyer, Ian M. Jones, Rainer Cramer   +3 more
wiley   +1 more source

Determination of Colistin Resistance in Clinical Isolates from Healthcare Facilities in Mthatha and Surrounding Areas

Antibiotics
Background: Antimicrobial resistance (AMR) is a global threat in the public healthcare sector. The emergence of carbapenem-resistant Enterobacterales (CRE) has become a serious public health threat in South Africa. The spread of CRE has led to the use of
Silindokuhle Ndlela, Ravesh Singh, Sandeep Vasaikar   +2 more
doaj   +1 more source

Prevalence of Carbapenemase and Extended-Spectrum β-Lactamase Producing Enterobacteriaceae: A Cross-Sectional Study

Antibiotics, 2023
Enterobacteriaceae have been classified as severely drug resistant bacteria by the World Health Organization due to their extensive production and dissemination of carbapenemases (CPs) and extended-spectrum β-lactamases (ESBL).
Muhammad Muqaddas Mustafai, Mavra Hafeez, Safa Munawar, Sakeenabi Basha, Ali A. Rabaan, Muhammad A. Halwani, Abdulsalam Alawfi, Amer Alshengeti, Mustafa A. Najim, Sara Alwarthan, Meshal K. AlFonaisan, Souad A. Almuthree, Mohammed Garout, Naveed Ahmed   +13 more
doaj   +1 more source