Results 11 to 20 of about 52,330 (263)

Parenteral carbapenems [PDF]

open access: yesClinical Microbiology and Infection, 2008
Among the many different structurally distinct classes of beta-lactams, the carbapenem class is regarded as that which is most potent and which has the widest spectrum of antimicrobial activity. Rapidly bactericidal, and demonstrating time-dependent killing, carbapenemes have a spectrum of antimicrobial activity that includes Gram-positive and Gram ...
Shah, P.M.
openaire   +4 more sources

New developments in carbapenems [PDF]

open access: yesClinical Microbiology and Infection, 2008
Antibiotic resistance among Gram-negative pathogens in hospitals is a growing threat to patients and is driving the increased use of carbapenems. Carbapenems are potent members of the beta-lactam family of antibiotics, with a history of safety and efficacy for serious infections that exceeds 20 years. Original and review articles were identified from a
Kattan, J.N.   +2 more
openaire   +4 more sources

Carbapenem Resistance: A Review [PDF]

open access: yesMedical Sciences, 2017
Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by ...
Francis S. Codjoe, Eric S. Donkor
doaj   +3 more sources

Medication errors associated with carbapenems [PDF]

open access: yesКачественная клиническая практика, 2018
Purpose. The purpose of this study was to discover the prevalence and types of medication errors associated with the use of carbapenems. Materials and methods.
A. V. Kuz’mina   +3 more
doaj   +1 more source

Zidovudine enhances activity of carbapenems against NDM-1-producing Enterobacteriaceae. [PDF]

open access: yes, 2021
OBJECTIVES: To investigate the efficacy of zidovudine in combination with carbapenems against NDM-1-producing Enterobacteriaceae. METHODS: MICs were determined using the broth microdilution method.
Hu, Y, Coates, A
core   +1 more source

Long-term carbapenems antimicrobial stewardship program [PDF]

open access: yes, 2020
: Objective. To evaluate clinical and antibiotic resistance impact of carbapenems stewardship programs. Methods: descriptive study, pre-post-intervention, between January 2012 and December 2019; 350-bed teaching hospital. Prospective audit and feedback
Álvarez Díaz, Hortensia   +5 more
core   +3 more sources

JMM Profile: Carbapenems: a broad-spectrum antibiotic [PDF]

open access: yes, 2021
Carbapenems are potent members of the β-lactam family that inhibit bacterial cell-wall biosynthesis inhibitors . They are highly effective against Gram-negative and Gram-positive drug-resistant infections .
Armstrong, Tom   +2 more
core   +1 more source

carbapenems

open access: yes, 2022
Archive of carbapenems containing sub-folders named after each compound and its net charge. Every compound's folder contains a total of 20 files distributed into three sub-directories reporting QM (QM/), FF (FF/), and MD (MD ...
Giuliano Malloci (2060875)   +5 more
core   +1 more source

Monooxygenases and Antibiotic Resistance: A Focus on Carbapenems [PDF]

open access: yes, 2023
Carbapenems are a group of broad-spectrum beta-lactam antibiotics that in many cases are the last effective defense against infections caused by multidrug-resistant bacteria, such as some strains of Klebsiella pneumoniae, Escherichia coli, Pseudomonas ...
Loqui, Davide   +5 more
core   +1 more source

Discrimination between Carbapenem-Resistant and Carbapenem-Sensitive Klebsiella pneumoniae Strains through Computational Analysis of Surface-Enhanced Raman Spectra: a Pilot Study

open access: yesMicrobiology Spectrum, 2022
In clinical settings, rapid and accurate diagnosis of antibiotic resistance is essential for the efficient treatment of bacterial infections. Conventional methods for antibiotic resistance testing are time consuming, while molecular methods such as PCR ...
Wei Liu   +9 more
doaj   +1 more source

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