Results 11 to 20 of about 65,238 (240)
Southwest Respiratory and Critical Care Chronicles, 2018 The development of antibiotics remains one of the great advances in medicine. Antibiotics have saved countless lives. Unfortunately, the widespread use of antimicrobials has led to the development of antimicrobial resistance.
David Sotello +2 more
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Carbapenems in clinical practice
Aktualʹnaâ Infektologiâ, 2019 Increasing frequency of infections caused by multi-drug resistant organisms is currently observed in the adult and pediatric population. It is the clinician’s responsibility to use wide-spectrum antibiotics when appropriate, where such a potent treatment
S.O. Kramarov, V.V. Yevtushenko
doaj +1 more source
Journal of Infection in Developing Countries, 2015 Introduction: The contribution of efflux systems to drug resistance in Enterobacteriaceae is becoming increasingly appreciated. This study phenotypically analyzed the role of efflux mechanisms in resistance to ertapenem, doripenem, and tigecycline among ...
Joel Filgona +2 more
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Multi-drug resistant Gram-negative bacteria: antibiotic-resistance and new treatment strategies [PDF]
, 2017 In this editorial, we treat the multi-drug-resistance of microorganisms such as Klebsiella pneumonia (Kp) and Acinetobacter baumanii and the issues concerning the management of these infections.
Angelis, Massimiliano De +2 more
core +1 more source
Clinical Microbiology and Infection, 2008 Among the many different structurally distinct classes of beta-lactams, the carbapenem class is regarded as that which is most potent and which has the widest spectrum of antimicrobial activity. Rapidly bactericidal, and demonstrating time-dependent killing, carbapenemes have a spectrum of antimicrobial activity that includes Gram-positive and Gram ...
openaire +2 more sources
Risk factors for hospital infections caused by carbapanem-resistant Acinetobacter baumannii
Journal of Infection in Developing Countries, 2016 Introduction: Acinetobacter baumannii is one of major causative agents of severe, life-threatening hospital infections (HIs), especially in intensive care units (ICUs).
Zorana M Djordjevic +5 more
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Microbiology Spectrum, 2022 In clinical settings, rapid and accurate diagnosis of antibiotic resistance is essential for the efficient treatment of bacterial infections. Conventional methods for antibiotic resistance testing are time consuming, while molecular methods such as PCR ...
Wei Liu +9 more
doaj +1 more source
Journal of Infection in Developing Countries, 2013 This item has no abstract. Use the links below to access the full text.
Atul Khajuria +3 more
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The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop [PDF]
, 2018 Carbapenems are "last resort" β-lactam antibiotics used to treat serious and life-threatening health care-associated infections caused by multidrug-resistant Gram-negative bacteria.
Alzari, Pedro M. +10 more
core +1 more source
Severe bloodstream infection due to KPC-producer e coli in a renal transplant recipient treated with the double-carbapenem regimen and analysis of in vitro synergy testing a case report [PDF]
, 2016 Transplant recipients are at high risk of infections caused by multidrug resistant microorganisms. Due to the limited thera- peutic options, innovative antimicrobial combinations against carbape- nem-resistant Enterobacteriaceae causing severe infections
CIPOLLA, ALESSIA +11 more
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