Results 21 to 30 of about 38,283 (181)
Проблеми екології та медицини, 2023 The aim of the study was to determine the correspondence between the carbapenemase genotype and the phenotypic antimicrobial profiles of P. aeruginosa. Materials and methods. The study included 51 clinical isolates of P.
N. Bahniuk +6 more
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Potentiation of antimicrobial activity of colistin with antibiotics of different groups against multidrug- and extensively drug-resistant strains of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2020 Objective. To reveal antibiotics being capable of potentiating the antimicrobial activity of colistin against multidrug- and extensively drug-resistant strains of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa. Materials and
Tapalskiy D.V. +3 more
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Carbapenem resistance in Canada [PDF]
Canadian Medical Association Journal, 2009 For more than 2 decades, carbapenems have been considered the pharmacotherapy of last resort for managing multidrug-resistant infections caused by Enterobacteriaceae bacteria (e.g., Escherichia coli and Salmonella ).
Baldwin, Toye +4 more
openaire +2 more sources
Journal of Antimicrobial Chemotherapy, 2020 AbstractBackgroundThe dissemination of MBLs compromises effective use of many β-lactams in the treatment of patients with life-threatening bacterial infections. Predicted global increases in the prevalence of MBL-producing carbapenem-resistant Enterobacterales (CRE) are being realized, yielding infections that are untreatable with existing therapies ...
Nicola Ooi +8 more
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Frontiers in Veterinary ScienceA total of 366 tonsillar tissue samples were collected from healthy free-range pigs owned by farmers across 12 districts in Baise City, Guangxi, China.
Yuan-Yuan Dai +24 more
doaj +1 more source
Frontiers in Microbiology, 2018 Carbapenems are last-resort antibiotics used in human medicine. The increased detection of carbapenem-resistant Enterobacteriaceae (CRE) is therefore worrying.
Nicole Roschanski +9 more
doaj +1 more source
Antibiotics, 2021 The Enterobacter cloacae complex is an emerging opportunistic pathogen whose increased resistance to carbapenems is considered a public health problem. This is due to the loss of efficacy of beta-lactam antibiotics, which are used as the first treatment ...
Aura Falco +6 more
doaj +1 more source
Sparing carbapenem usage [PDF]
Journal of Antimicrobial Chemotherapy, 2017 Carbapenem resistance in Gram-negative bacteria is increasing in many countries and use of carbapenems and antibiotics to which resistance is linked should be reduced to slow its emergence. There are no directly equivalent antibiotics and the alternatives are less well supported by clinical trials.
openaire +3 more sources
Advanced Science, EarlyView.This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing +10 more
wiley +1 more source
Advanced Science, EarlyView.Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang +9 more
wiley +1 more source