Results 171 to 180 of about 187,315 (266)

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Identification of a C₂H₂ Transcription Factor (PsCZF3) Associated with RxLR Effectors and Carbohydrate-Active Enzymes in Phytophthora sojae Based on WGCNA. [PDF]

J Fungi (Basel), 2022
Hu Y, He Z, Kang Y, Ye W, Cui L.
europepmc   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

Advanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao, Mei Li, Mengjiao Fan, Chuanhuan Liu, Jie Jiang, Jia Song, Yingzhu Liu   +6 more
wiley   +1 more source

Thermophiles and carbohydrate-active enzymes (CAZymes) in biofilm microbial consortia that decompose lignocellulosic plant litters at high temperatures. [PDF]

Sci Rep, 2022
Liew KJ, Liang CH, Lau YT, Yaakop AS, Chan KG, Shahar S, Shamsir MS, Goh KM.   +7 more
europepmc   +1 more source

Water deficits in wheat: Fructan exohydrolase (1-FEH) mRNA expression and relationship to soluble carbohydrate concentrations in two varieties

, 2009
Terminal drought is a risk for wheat production in many parts of the world. Robust physiological traits for resilience would enhance the preselection of breeding lines in drought-prone areas.
Setter, T., Dell, B., Conocono, E., Waters, I., Appels, R., Zhang, J.   +5 more
core  

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

Shaping the Glycan Landscape: Hidden Relationships between Linkage and Ring Distortions Induced by Carbohydrate-Active Enzymes. [PDF]

J Am Chem Soc
Grothaus IL, Spellerberg P, Rovira C, Colombi Ciacchi L.   +3 more
europepmc   +1 more source

Survey of the genome of opitutus terrae and other organisms for novel carbohydrate-active enzyme specificities

Lignocellulose is the major component of the plant cell wall and is a sustainable source of inexpensive abundant biomass. Efficient degradation of the lignocellulosic polysaccharides, cellulose and hemicellulose, is required if the plant cell wall is to ...
Bawn, Maria
core  

Precision Lignocellulosic Biorefinery: Process Regulation From Corn Stover to Products

Advanced Science, EarlyView.
This study presents a precision biorefinery framework that transforms corn stover into high‐value bioproducts through whole‐process regulation. Mechanical fractionation separates feedstock into parenchyma‐rich short fibers and vascular‐bundle‐dominant long fibers.
Xue‐Cheng Lin, Lan Wang, Tai‐Ran Pang, Ming‐Yuan Yin, Hong‐Zhang Chen   +4 more
wiley   +1 more source

Genomic and transcriptomic characterization of carbohydrate-active enzymes in the anaerobic fungus Neocallimastix cameroonii var. constans. [PDF]

G3 (Bethesda)
Blair EM, Navaratna TA, Ahern CB, Ragunathan R, Brown JL, Mondo SJ, Lipzen A, Hanafy RA, LaButti K, Talag J, Barry K, Chovatia M, Wang M, Gonzalez J, Peng X, Grigoriev IV, O'Malley MA.   +16 more
europepmc   +1 more source