Results 21 to 30 of about 69 (58)

Late Stage Mannan Metabolism in Cellvibrio japonicus Requires the Combined Action of a Mannosyl‐Glucose Phosphorylase and a Mannobiose Epimerase

open access: yesMolecular Microbiology, Volume 125, Issue 2, Page 173-184, February 2026.
Model for the non‐PTS utilization of manno‐oligosaccharides by Cellvibrio japonicus. The Mgp130A and EpiA enzymes are essential for the utilization of mannose residues. ABSTRACT Manno‐oligosaccharides and their metabolism play important roles in gut health, pharmaceutical development, and renewable chemical production.
Jessica K. Novak, Jeffrey G. Gardner
wiley   +1 more source

Metabolo‐Transcriptomics Analyses Reveal Alfalfa Adaptation to Combined Saline‐Alkali and Low‐Temperature Stress in the Field

open access: yesPlant Biotechnology Journal, Volume 24, Issue 2, Page 504-519, February 2026.
ABSTRACT Alfalfa (Medicago sativa L.) is known as the ‘King of Forage’ because of its high protein content and excellent palatability. Alfalfa productivity is adversely affected in cold regions with saline‐alkali soils. However, the mechanisms underlying the response of alfalfa to combined saline‐alkali and low‐temperature stress under field conditions
Rui Guo   +8 more
wiley   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou   +9 more
wiley   +1 more source

Diversity and Ecological Potentials of Marine Viruses Inhabiting Continental Shelf Seas

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
To the best of the knowledge, this study provides the largest viral genome dataset from a continental shelf sea. It reveals that over half of vOTUs are novel, highlighting the remarkable viral novelty in the eastern continental shelf seas of China (ECSSC).
Xiaoyue Guo   +9 more
wiley   +1 more source

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 1, Page 193-206, January 2026.
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen   +12 more
wiley   +1 more source

Biochemical Characterization of an Atypical Variant Flanking or Affecting the Initiation or Start Methionine Codon in CHST14 in a Patient With Musculocontractural Ehlers–Danlos Syndrome

open access: yesProteoglycan Research, Volume 4, Issue 1, January 2026.
ABSTRACT Musculocontractural Ehlers‐Danlos syndrome (EDS) caused by pathogenic variants in the carbohydrate sulfotransferase 14 gene (CHST14) (mcEDS‐CHST14) is an autosomal recessive connective tissue disorder characterized by congenital malformations including specific craniofacial features, congenital multiple contractures, and progressive fragility ...
Shuji Mizumoto   +7 more
wiley   +1 more source

Genomic and Phenotypic Bases of Salt Tolerance in Sinorhizobium meliloti: Candidate Traits for Bioinoculant Development Addressing Saline Soils

open access: yesMicrobial Biotechnology, Volume 19, Issue 1, January 2026.
Genome‐wide association analysis on 49 Sinorhizobium meliloti strains (21 de novo sequenced) reveals extensive phenotypic heterogeneity in salt tolerance, closely associated with quorum sensing, cell surface stability and adaptation. Salt‐tolerant strains exhibit a wider metabolic capacity, especially in carbon sources exploitation, underscoring their ...
Agnese Bellabarba   +12 more
wiley   +1 more source

Structural characterisation of nucleotide sugar short‐chain dehydrogenases/reductases from the thermophilic pseudomurein‐containing methanogen Methanothermobacter thermautotrophicus ΔH

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 492-513, January 2026.
Nucleotide sugar short‐chain dehydrogenases/reductases (NS‐SDRs) are involved in pseudomurein and capsular polysaccharide formation in methanogenic Archaea. Methanothermobacter thermautotrophicus possesses several NS‐SDRs labelled Mth375, Mth380, Mth373, Mth631 and Mth1789.
Vincenzo Carbone   +4 more
wiley   +1 more source

Glucose-6-Phosphate 1-Epimerase Responds to Phosphate Starvation by Regulating Carbohydrate Homeostasis in Rice and Arabidopsis [PDF]

open access: gold
Hongkai Zhang   +23 more
openalex   +1 more source

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