Results 101 to 110 of about 13,653 (252)

Pharmahuasca, anahuasca y vino de jurema

Cultura y Droga, 2001
Este resumen es presentado de un auto-experimentos humano o bioensayo psiconáutico de pharmahuasca -cápsulas que contienen NN-dimethyltryptamina cristalina (DMT) más harmina, así como una combinación de otras triptaminas psicoactivas con otros 13 ...
Jonathan Ott, Mariela Nárvaez Marin
doaj  

Pd(II)-catalyzed C–H annulation and lactonization of indole-2-carboxamides with hydroxyalkynoates using air as an oxidant

Tetrahedron Chem
A novel palladium(II) catalyzed C–H annulation strategy has been developed for the synthesis of a diverse range of furo[3′,4':5,6]pyrido[3,4-b]indole-1,5(3H)-dione scaffolds. This is the first report on the construction of polycyclic carboline frameworks
Kiran Aswale, Rajashaker Bantu, B. Sridhar, B.V. Subba Reddy   +3 more
doaj   +1 more source

Synthesis of Carbolines by Photostimulated Cyclization of Anilinohalopyridines

, 2016
A general synthetic route to prepare all four carboline regioisomers by photostimulated cyclization of anilinohalopyridines is described. The methodology affords various substituted carbolines in good to excellent yields. In the case of α-carbolines, the
Silvia M. Barolo (1687936), Roberto A. Rossi (1687933), Joydev K. Laha (1470892), Gregory D. Cuny (249276)   +3 more
core   +1 more source

Effects of harmane, norharmane and harmine on apomorphine-induced pecking behavior in chick

Journal of Mazandaran University of Medical Sciences, 2009
.(Received 3 January, 2009; Accepted 27 May, 2009)AbstractBackground and purpose: -carboline alkaloids, also known as harmala's alkaloids have a wide spectrum of pharmacological actions including a stimulatory action on release of dopamine and other ...
Davood Farzin, Elika Salimi
doaj  

Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine

Beilstein Journal of Organic Chemistry, 2011
The carboline ring system is an important pharmacophore found in a number of biologically important targets. Development of synthetic routes for the preparation of these compounds is important in order to prepare a range of analogues containing the ...
Jessica Baiget, Sabin Llona-Minguez, Stuart Lang, Simon P. MacKay, Colin J. Suckling, Oliver B. Sutcliffe   +5 more
doaj   +1 more source

Long-term retention of neurotoxic beta-carbolines in brain neuromelanin

, 2003
beta-Carbolines show structural resemblance to the neurotoxic N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and are metabolized to mitochondrial toxicants.
Annas, A, Skog, K, Lindquist, Nils Gunnar,, Brittebo, Eva,, Brittebo, E B, Lindquist, N G, Brittebo, Eva B,, Annas, A,, Östergren, A,, Skog, Kerstin,, Skog, Kerstin, Ostergren, A, Östergren, Anna,, Lund University., Annas, Anita,   +14 more
core   +1 more source

The role of beta-carbolines (harman/norharman) in heroin addicts

, 1995
SummaryEndogenous substances resulting from interactions between alcohol and possibly opioid metabolites and neurotransmitters (dopamine, indolamines) could be mediators of the pathochemical process towards dependence.
D Ladewig, R Stohler, H Rommelspacher
core   +1 more source

Synthesis of 1,4‐Disubstituted and 1‐Substituted β‐Carbolines via 3‐Substituted 2‐Acylindoles [PDF]

β-Carbolines represent a large class of bioactive natural products, whereby most of these alkaloids bear residues at C1, and occasionally at C3, and only limited examples of 1,4-disubstituted β-carbolines are known.
Untergehrer, Martin, Jourjine, Ilya A. P., Bracher, Franz, Thees, Katharina   +3 more
core   +1 more source

β-Carbolines as specific inhibitors of cyclin-Dependent kinases

, 2002
Harmine (3), 7-fluoro-1-methyl β-carboline (35) and 1-(5-methyl-imidazol-4-yl) β-carboline (41) were potent and specific inhibitors of cyclin-dependent kinases.
Wang, Jian, Wang, Jerry H., Yongcheng Song, Qi, Robert Zhong, Teng, Su Fern, Sim, Mui Mui, Yu Deng, Robert Zhong Qi, Su Fern Teng, Jerry H. Wang, Kesuma, Djohan, Deng, Yu, Song, Yongcheng, Jinao Duan, Mui Mui Sim, Jian Wang, Djohan Kesuma, Duan, Jinao   +17 more
core   +1 more source

HETEROCYCLIC SYNTHESIS USING NITRILIMINES: PART 18. SYNTHESIS OF NEW FUSED HETEROCYCLES CONTAINING TRIAZINONE MOIETY

Makara Seri Sains, 2011
A series of new 4,5-dihydro-6-oxo-1,2,4-triazino[4,5-b]1,2,3,4-tetrahydro-β-carbolines were synthesized by the reactionof methyl 1,2,3,4-tetrahydro-β-carboline-3-carboxylate and the appropriate hydrazonoyl halide in presence oftriethylamine.
Hany Mahmod Dalloul
doaj