An Improved Synthesis of α-Carbolines under Microwave Irradiation
, 2016 α-Carbolines are interesting core structures for designing DNA-interacting small molecules. However, these compounds are not commercially available and their synthetic methods are low yielding or time consuming. The shortest synthetic route, the modified
Ramón Alajarín (2652634) +3 more
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Inhibition of Monoamine Oxidase from Bovine Retina by β-Carbolines
, 1994 The behaviour of some β-carboline derivatives as inhibitors of monoamine oxidase has been studied in bovine retina. Inhibition was found not to show any significant time dependence.
M Unzeta +3 more
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A QSAR study of a series of beta-carbolines.
, 1989 The relationship between chemical structure and biological activity of a series of beta-carbolines is studied. A chromatographic system based on Thin Layer Chromatography is used to experimentally determine lipophilicity of the investigated beta ...
G. L. Biagi +5 more
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Modulation of GABA-stimulated chloride influx by beta-carbolines in rat brain membrane vesicles
, 1988 We have shown that GABA-stimulated chloride influx into membrane vesicles from the rat cerebral cortex can be enhanced or inhibited by β-carbolines.
SERRA, MARIANGELA +4 more
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Biocatalytic asymmetric formation of tetrahydro-β-carbolines
, 2010 Strictosidine synthase triggers the formation of strictosidine from tryptamine and secologanin, thereby generating a carbon-carbon bond and a new stereogenic center.
Sarah E. O’Connor +8 more
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Metal free one pot synthesis of β-carbolines via a domino Pictet-Spengler reaction and aromatization
, 2019 A convenient and efficient metal free, atom economical flexible synthesis of β-carbolines involving a domino Pictet-Spengler reaction and aromatization in oxygen atmosphere in N-methyl-2-pyrollidone (NMP) is described.
Balasubramanian, K.K. +5 more
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Oxidation of Tetrahydro-β-carbolines by Persulfate
, 2019 The development of persulfate-mediated oxidation of tetrahydro-β-carbolines is reported. This mild reaction facilitates the formation of a variety of 2-formyl N-substituted tryptamines and the related derivatives as key intermediates in moderate to ...
Haijun Chen (580445) +7 more
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Catalytic enantioselective nitrone cycloadditions enabling collective syntheses of indole alkaloids
Nature CommunicationsTetrahydro-β-carboline skeletons are prominent and ubiquitous in an extraordinary range of indole alkaloid natural products and pharmaceutical compounds. Powerful synthetic approaches for stereoselective synthesis of tetrahydro-β-carboline skeletons have
Xiaochen Tian +9 more
doaj +1 more source
Synthesis of some gbs-carbolines derived from (gbs-methyltryptophan)
, 1984 Ball State University LibrariesLibrary services and resources for knowledge buildingMasters ThesesThere is no abstract available for this thesis.Thesis (M.S.)--Ball State University ...
Ogle, Mark E.
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Design and Synthesis of Fluorescent 1,3-Diaryl-β-carbolines and 1,3-Diaryl-3,4-dihydro-β-carbolines
ACS Omega, 2021 JiYang Pu +5 more
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