Results 131 to 140 of about 2,640 (185)
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2000
Abstract Interaction of potential environmental neurotoxins with genetic susceptibility is considered important in the etiology of idiopathic PD (43,64,101). N-Methylated /3Cs and IQs, which contain pyridinium moieties like MPP+ and can in hibit mitochondrial respiration, are reasonable candidatesages, but their pyrolytic formation ...
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Abstract Interaction of potential environmental neurotoxins with genetic susceptibility is considered important in the etiology of idiopathic PD (43,64,101). N-Methylated /3Cs and IQs, which contain pyridinium moieties like MPP+ and can in hibit mitochondrial respiration, are reasonable candidatesages, but their pyrolytic formation ...
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ChemInform Abstract: CARBOLINE 1. MITT. 1,4‐DISUBSTITUIERTE BETA‐CARBOLINE
Chemischer Informationsdienst. Organische Chemie, 1970AbstractDie Umsetzung der Oxime (I) mit Phosphorpentachlorid in Nitrobenzol liefert unter Beckmann‐Umlagerung bei 45‐70°C die Dihydrocarboline (II), die sich in wäßriger Lösung in Form ihrer Hydrochloride mit Palladium und Maleinsäure zu den β‐Carbolinen (III) dehydrieren lassen.
K. I. KUCKOVA +2 more
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METHODOLOGIES FOR THE SYNTHESIS OF β-CARBOLINES [PDF]
β-Carbolines are an important class of heterocyclic compounds that are widely distributed in nature, being found in several families of naturally occurring alkaloids. Due to their diverse biological activities, the synthesis of β-carbolines is of high importance.
Boswood, S, Roesner, S
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Photodissociation of β-carboline
Journal of Photochemistry, 1986Abstract An explanation for the photochemical homolytic self-dissociation of β-carboline has been found by means of intermediate neglect of differential overlap (INDO) and complete neglect of differential overlap/spectroscopic parametrization (CNDO/S) molecular orbital calculations.
A. Sánchez-de-Merás +3 more
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Neurobiology of tetrahydro-β-carbolines
Life Sciences, 1980Abstract Tetrahydro-β-carbolines (THβC's) are tricyclic compounds structurally related to the indoleamines. Recent studies have reported the in vitro and in vivo formation of these compounds in brain and other tissues. This information and other data indicating that THβC's interact relatively specifically with various aspects ...
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Tetrahedron Letters, 2016
Abstract Herein, we report a facile synthesis of 3,4-dihydro-β-carbolines and aromatic β-carbolines from tetrahydro-β-carbolines, mediated by N -bromosuccinimide in toluene at 0 °C to room temperature (rt), in good to moderate yields.
Santanu Hati, Subhabrata Sen
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Abstract Herein, we report a facile synthesis of 3,4-dihydro-β-carbolines and aromatic β-carbolines from tetrahydro-β-carbolines, mediated by N -bromosuccinimide in toluene at 0 °C to room temperature (rt), in good to moderate yields.
Santanu Hati, Subhabrata Sen
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Anticancer mechanisms of β‐carbolines
Chemical Biology & Drug DesignAbstractβ‐Carboline nucleus is therapeutically valuable in medicinal chemistry for the treatment of varied number of diseases, most importantly cancer. The potent and wide‐ranging activity of β‐carboline has established them as imperative pharmacological scaffolds especially in the cancer treatment. Numerous derivatives such as Tetrahydro β‐carbolines,
Shivam Mishra +3 more
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