Results 91 to 100 of about 4,239 (221)

Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine

Beilstein Journal of Organic Chemistry, 2011
The carboline ring system is an important pharmacophore found in a number of biologically important targets. Development of synthetic routes for the preparation of these compounds is important in order to prepare a range of analogues containing the ...
Jessica Baiget, Sabin Llona-Minguez, Stuart Lang, Simon P. MacKay, Colin J. Suckling, Oliver B. Sutcliffe   +5 more
doaj   +1 more source

β-Carbolines as specific inhibitors of cyclin-Dependent kinases

, 2002
Harmine (3), 7-fluoro-1-methyl β-carboline (35) and 1-(5-methyl-imidazol-4-yl) β-carboline (41) were potent and specific inhibitors of cyclin-dependent kinases.
Wang, Jian, Wang, Jerry H., Yongcheng Song, Qi, Robert Zhong, Teng, Su Fern, Sim, Mui Mui, Yu Deng, Robert Zhong Qi, Su Fern Teng, Jerry H. Wang, Kesuma, Djohan, Deng, Yu, Song, Yongcheng, Jinao Duan, Mui Mui Sim, Jian Wang, Djohan Kesuma, Duan, Jinao   +17 more
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An Improved Synthesis of α-Carbolines under Microwave Irradiation

, 2016
α-Carbolines are interesting core structures for designing DNA-interacting small molecules. However, these compounds are not commercially available and their synthetic methods are low yielding or time consuming. The shortest synthetic route, the modified
Ramón Alajarín (2652634), Julio Alvarez-Builla (1784356), Juan J. Vaquero (449603), Patricia Vera-Luque (2652637)   +3 more
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Modulation of GABA-stimulated chloride influx by beta-carbolines in rat brain membrane vesicles

, 1988
We have shown that GABA-stimulated chloride influx into membrane vesicles from the rat cerebral cortex can be enhanced or inhibited by β-carbolines.
SERRA, MARIANGELA, Ikeda M, Yamamura H.I., Malatynska E, Biggio G   +4 more
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From the Behavioral Pharmacology of Beta-Carbolines to Seizures, Anxiety, and Memory

The Scientific World Journal, 2007
A number of beta-carbolines are inverse agonists of the GABA-A receptor complex, acting on the benzodiazepine site. They show convulsive properties when administered at high doses, anxiogenic properties at moderate doses, and learning-enhancing effects ...
Patrice Venault, Georges Chapouthier
doaj   +1 more source

Inhibition of Monoamine Oxidase from Bovine Retina by β-Carbolines

, 1994
The behaviour of some β-carboline derivatives as inhibitors of monoamine oxidase has been studied in bovine retina. Inhibition was found not to show any significant time dependence.
M Unzeta, M D Balsa, J M Lizcano, A. Fernández De Arribam   +3 more
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HETEROCYCLIC SYNTHESIS USING NITRILIMINES: PART 18. SYNTHESIS OF NEW FUSED HETEROCYCLES CONTAINING TRIAZINONE MOIETY

Makara Seri Sains, 2011
A series of new 4,5-dihydro-6-oxo-1,2,4-triazino[4,5-b]1,2,3,4-tetrahydro-β-carbolines were synthesized by the reactionof methyl 1,2,3,4-tetrahydro-β-carboline-3-carboxylate and the appropriate hydrazonoyl halide in presence oftriethylamine.
Hany Mahmod Dalloul
doaj  

Biocatalytic asymmetric formation of tetrahydro-β-carbolines

, 2010
Strictosidine synthase triggers the formation of strictosidine from tryptamine and secologanin, thereby generating a carbon-carbon bond and a new stereogenic center.
Sarah E. O’Connor, Bernhardt, Peter, Usera, Aimee R., O'Connor, S., Bernhardt, P., Peter Bernhardt, Aimee R. Usera, O'Connor, Sarah E., Usera, A.   +8 more
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Metal free one pot synthesis of β-carbolines via a domino Pictet-Spengler reaction and aromatization

, 2019
A convenient and efficient metal free, atom economical flexible synthesis of β-carbolines involving a domino Pictet-Spengler reaction and aromatization in oxygen atmosphere in N-methyl-2-pyrollidone (NMP) is described.
Balasubramanian, K.K., Ramu, S., Baskar, B., Srinath, S., Ilango, K., kumar, A. Aswin   +5 more
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Synthesis of some gbs-carbolines derived from (gbs-methyltryptophan)

, 1984
Ball State University LibrariesLibrary services and resources for knowledge buildingMasters ThesesThere is no abstract available for this thesis.Thesis (M.S.)--Ball State University ...
Ogle, Mark E.
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