Results 91 to 100 of about 6,872 (221)

Locus coeruleus complex of the family Delphinidae [PDF]

open access: yes, 2018
The locus coeruleus (LC) is the largest catecholaminergic nucleus and extensively projects to widespread areas of the brain and spinal cord. The LC is the largest source of noradrenaline in the brain.
Arbelo, Manuel   +6 more
core   +2 more sources

Nicotinamide N-methyltransferase catalyses the N-methylation of the endogenous ß-carboline norharman: evidence for a novel detoxification pathway [PDF]

open access: yes, 2016
Nicotinamide N-methyltransferase (NNMT) is responsible for the N-methylation of nicotinamide to 1-methylnicotinamide. Our recent studies have demonstrated that NNMT regulates cellular processes fundamental to the correct functioning and survival of the ...
Barlow, David J   +10 more
core   +2 more sources

Pharmahuasca, anahuasca y vino de jurema

open access: yesCultura y Droga, 2001
Este resumen es presentado de un auto-experimentos humano o bioensayo psiconáutico de pharmahuasca -cápsulas que contienen NN-dimethyltryptamina cristalina (DMT) más harmina, así como una combinación de otras triptaminas psicoactivas con otros 13 ...
Jonathan Ott, Mariela Nárvaez Marin
doaj  

Pd(II)-catalyzed C–H annulation and lactonization of indole-2-carboxamides with hydroxyalkynoates using air as an oxidant

open access: yesTetrahedron Chem
A novel palladium(II) catalyzed C–H annulation strategy has been developed for the synthesis of a diverse range of furo[3′,4':5,6]pyrido[3,4-b]indole-1,5(3H)-dione scaffolds. This is the first report on the construction of polycyclic carboline frameworks
Kiran Aswale   +3 more
doaj   +1 more source

Salsolinol: an Unintelligible and Double-Faced Molecule—Lessons Learned from In Vivo and In Vitro Experiments [PDF]

open access: yes, 2017
Salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline) is a tetrahydroisoquinoline derivative whose presence in humans was first detected in the urine of Parkinsonian patients on l-DOPA (l-dihydroxyphenylalanine) medication.
Bugajski, Andrzej   +3 more
core   +2 more sources

Effects of harmane, norharmane and harmine on apomorphine-induced pecking behavior in chick

open access: yesJournal of Mazandaran University of Medical Sciences, 2009
.(Received 3 January, 2009; Accepted 27 May, 2009)AbstractBackground and purpose: -carboline alkaloids, also known as harmala's alkaloids have a wide spectrum of pharmacological actions including a stimulatory action on release of dopamine and other ...
Davood Farzin, Elika Salimi
doaj  

Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine

open access: yesBeilstein Journal of Organic Chemistry, 2011
The carboline ring system is an important pharmacophore found in a number of biologically important targets. Development of synthetic routes for the preparation of these compounds is important in order to prepare a range of analogues containing the ...
Jessica Baiget   +5 more
doaj   +1 more source

De bijdrage van toevoeging van cacao aan tabak aan rookverslaving [PDF]

open access: yes, 2003
In this report the effect of these compounds on the addiction to cigarette smoking was assessed, using currently available information in the literature on psychoactive compounds of cocoa.
Andel I van   +6 more
core  

From the Behavioral Pharmacology of Beta-Carbolines to Seizures, Anxiety, and Memory

open access: yesThe Scientific World Journal, 2007
A number of beta-carbolines are inverse agonists of the GABA-A receptor complex, acting on the benzodiazepine site. They show convulsive properties when administered at high doses, anxiogenic properties at moderate doses, and learning-enhancing effects ...
Patrice Venault, Georges Chapouthier
doaj   +1 more source

HETEROCYCLIC SYNTHESIS USING NITRILIMINES: PART 18. SYNTHESIS OF NEW FUSED HETEROCYCLES CONTAINING TRIAZINONE MOIETY

open access: yesMakara Seri Sains, 2011
A series of new 4,5-dihydro-6-oxo-1,2,4-triazino[4,5-b]1,2,3,4-tetrahydro-β-carbolines were synthesized by the reactionof methyl 1,2,3,4-tetrahydro-β-carboline-3-carboxylate and the appropriate hydrazonoyl halide in presence oftriethylamine.
Hany Mahmod Dalloul
doaj  

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