Results 71 to 80 of about 6,872 (221)
Журнал органічної та фармацевтичної хімії, 2020 Aim. To synthesize 4-cyanoindolo[2,3-c]pyrilium salts and examine their reactivity towards N-nucleophiles. Results and discussion. The acylation reaction of 2-(indolyl-3)-2-aroylacetonitriles under acid catalysis conditions was studied. 4-Cyanoindolo[2,3-
N. M. Bogdan +2 more
doaj +1 more source
Thiourea-Catalyzed Enantioselective Iso-Pictet-Spengler Reactions [PDF]
, 2011 A one-pot condensation of isotryptamines and aldehydes that affords enantiomerically enriched 4-substituted tetrahydro-\(\gamma\)-carbolines is reported. The reaction is induced by a chiral thiourea/benzoic acid dual catalyst system.
Jacobsen, Eric N. +2 more
core +1 more source
Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature
Ecology and Evolution, Volume 16, Issue 4, April 2026.This study explores the evolutionary role of psilocybin, the psychedelic compound found in Psilocybe mushrooms. We provide the first experimental tests of defence and community‐level evidence for invertebrate responses to psilocybin‐producing fungi, revealing significant negative effects on invertebrate locomotion, development, and survival.
K. J. Matthews Nicholass +16 more
wiley +1 more source
Design, synthesis, and subtype selectivity of 3,6-disubstituted b-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse [PDF]
, 2010 A series of 3,6-disubstituted ß-carbolines was synthesized and evaluated for their in vitro affinities at axß3V2 GABAA/benzodiazepine receptor subtypes by radioligand binding assays in search of a1 subtype selective ligands to treat alcohol abuse ...
Clayton, T +10 more
core
Changes in serine metabolism by a serum factor present in a group of episodic psychotic patients [PDF]
, 1991 __Abstract__ Addition of serum, obtained from patients suffering from an acute psychosis characterized by dysperceptions, to the culture media of fibroblasts altered the amino acid metabolism in these cells.
Bruinvels, J. +2 more
core +1 more source
Da Yuan Yin Regulates Gut Microbiota and Improves Intestinal Injury in Sepsis
Food Science &Nutrition, Volume 14, Issue 4, April 2026.Sepsis mouse model was induced by LPS to investigate the effect of Da Yuan Yin (DYY) in vivo. Hematoxylin–eosin staining showed that DYY could reduce intestinal injury caused by sepsis. In addition, DYY can also inhibit inflammation, apoptosis, and promote cell proliferation in sepsis, and promote the expression of tight junction proteins.
Li Wang +4 more
wiley +1 more source
1-Ethyl-3-nitroquinolin-4(1H)-one
IUCrData, 2016 The title compound, C11H10N2O3, was obtained as side-product in a project focussing on the synthesis of carbolines. It was prepared from nitroquinolinone, ethanol and phosphoryl chloride.
Daniel Limbach +3 more
doaj +1 more source
In vitro antiviral effects of Peganum harmala seed extract and its total alkaloids against Influenza virus [PDF]
, 2017 This research was aimed to evaluate the in vitro antiviral effect and the mechanism of the effect of Peganum. harmala seeds extract against influenza A virus infection using Madin-Darby canine kidney (MDCK) cells.
Fotouhi, F. +3 more
core +1 more source
Food Science &Nutrition, Volume 14, Issue 4, April 2026.• A novel QuEChERS‐UPLC‐MS/MS method was successfully developed for the simultaneous determination of two β‐carboline heterocyclic amines and seven mycotoxins in fried foods. ABSTRACT Dietary exposure to both processing contaminants and natural toxins in fried foods poses a potential health risk, but analytical methods for their simultaneous monitoring
Diaodiao Yang +6 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2014 A novel synthetic methodology has been developed for the synthesis of dihydro-β-carboline derivatives employing oxidative amidation–Bischler–Napieralski reaction conditions using tryptamine and 2,2-dibromo-1-phenylethanone as key starting materials.
Suresh Babu Meruva +4 more
doaj +1 more source