Results 61 to 70 of about 4,239 (221)
, 2018 A Pd(OAc)2-catalyzed asymmetric cyclization of 2-aminoaryl alkynones involving an intramolecular trans-aminopalladation of alkyne and 1,2-addition to the carbonyl group tandem processes was developed.
Junjie Chen +5 more
core +1 more source
Natural surfactants assisted an efficient synthesis of tetrahydro-β-carbolines
Results in Chemistry, 2021 An expeditious protocol for the synthesis of structurally diversified β-carboline derivatives has been reported using a readily available natural surfactant medium.
Somnath S. Gholap, Vinod R. Kadu
doaj +1 more source
A Versatile Linkage Strategy for Solid-Phase Synthesis of N,N-Dimethyltryptamines and β-Carbolines
, 2016 Various tryptamines are captured by a vinylsulfonylmethyl polystyrene resin, generating a safety-catch linkage. β-Carbolines can be formed from 4 by a Pictet−Spengler reaction with the introduction of R1. Tryptamine 4 can also be derivatized by acylation
Peter G. Schultz (183240) +1 more
core +1 more source
Журнал органічної та фармацевтичної хімії, 2020 Aim. To synthesize 4-cyanoindolo[2,3-c]pyrilium salts and examine their reactivity towards N-nucleophiles. Results and discussion. The acylation reaction of 2-(indolyl-3)-2-aroylacetonitriles under acid catalysis conditions was studied. 4-Cyanoindolo[2,3-
N. M. Bogdan +2 more
doaj +1 more source
Phytochemicals in Asthma Management: Mechanism, Translational Gap and Clinical Integration
Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.The phytochemicals including flavonoids, alkaloids, terpenoids, and saponins modulate inflammatory, oxidative, and immune pathways in asthma. It highlights their mechanisms of action, translational challenges, advanced formulation strategies, and emerging clinical potential as adjunct therapies for precision‐based asthma management.
Pulak Majumder, Trisita Majumder
wiley +1 more source
A New Synthetic Approach to the Preparation of Indolo[3,2‐c]quinolines From Sulfonylalkyl Indoles
Advanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.Functionalized indolo[3,2‐c]quinolines can be efficiently prepared from sulfonylalkyl indoles by a cascade process involving reduction, vinylogous aza‐Michael and aromatization reactions triggered by zinc powder in acetic acid at reflux. The reductive cyclization of sulfonylalkyl indoles obtained from 2‐(o‐nitroaryl)indoles, provides an efficient ...
Francesca Cecchini +3 more
wiley +1 more source
β-Carbolines in Experiments on Laboratory Animals
, 2020 Some studies have ascribed a protective effect against neurodegenerative diseases to the β-carbolines harman (H) and norharman (NH), which occur mostly in coffee and coffee substitutes.
Elżbieta Wojtowicz +9 more
core +1 more source
1-Ethyl-3-nitroquinolin-4(1H)-one
IUCrData, 2016 The title compound, C11H10N2O3, was obtained as side-product in a project focussing on the synthesis of carbolines. It was prepared from nitroquinolinone, ethanol and phosphoryl chloride.
Daniel Limbach +3 more
doaj +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 18, 14 May 2026.The total synthesis of the manzamine alkaloid keramamine C (2) in its racemic form was achieved in 5 steps, with ring‐closing metathesis as the key step. The metathesis is strongly improved by an intramolecular H‐bond‐induced conformational fixation of the amide bond, inducing close proximity of the terminal double bonds in the precursor molecule.
Jana Ganzmann +4 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2014 A novel synthetic methodology has been developed for the synthesis of dihydro-β-carboline derivatives employing oxidative amidation–Bischler–Napieralski reaction conditions using tryptamine and 2,2-dibromo-1-phenylethanone as key starting materials.
Suresh Babu Meruva +4 more
doaj +1 more source