Results 81 to 90 of about 4,239 (221)

Sc(OTf)₃‑Catalyzed C2-Selective Cyanation/Defluorination Cascade of Perfluoroalkylated 3‑Indolylmethanols and Application to the Synthesis of 3‑Fluoro(perfluoroalkyl)-β-carbolines

An unprecedented Sc­(OTf)3-catalyzed C2-selective cyanation/defluorination cascade of perfluoroalkylated 3-indolylmethanols with TMSCN is described, which provides a novel and practical strategy for the synthesis of structurally diverse 3-(2-cyano ...
Weidong Rao (1598017), Dandan Shang (11458496), Jichao Chen (108786), Qing Bao (1852243), Li Feng (77923), Jingjing Sang (11458493), Rui Hu (505795)   +6 more
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Long-term retention of neurotoxic beta-carbolines in brain neuromelanin

, 2003
beta-Carbolines show structural resemblance to the neurotoxic N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and are metabolized to mitochondrial toxicants.
Annas, A, Skog, K, Lindquist, Nils Gunnar,, Brittebo, Eva,, Brittebo, E B, Lindquist, N G, Brittebo, Eva B,, Annas, A,, Östergren, A,, Skog, Kerstin,, Skog, Kerstin, Ostergren, A, Östergren, Anna,, Lund University., Annas, Anita,   +14 more
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Synthesis of Carbolines by Photostimulated Cyclization of Anilinohalopyridines

, 2016
A general synthetic route to prepare all four carboline regioisomers by photostimulated cyclization of anilinohalopyridines is described. The methodology affords various substituted carbolines in good to excellent yields. In the case of α-carbolines, the
Silvia M. Barolo (1687936), Roberto A. Rossi (1687933), Joydev K. Laha (1470892), Gregory D. Cuny (249276)   +3 more
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Pharmahuasca, anahuasca y vino de jurema

Cultura y Droga, 2001
Este resumen es presentado de un auto-experimentos humano o bioensayo psiconáutico de pharmahuasca -cápsulas que contienen NN-dimethyltryptamina cristalina (DMT) más harmina, así como una combinación de otras triptaminas psicoactivas con otros 13 ...
Jonathan Ott, Mariela Nárvaez Marin
doaj  

New reactions of 2-methyleneaziridines [PDF]

Chapter One reviews the synthesis, properties and reactions of 2-methyleneaziridines, the subject of this thesis. Chapter Two describes the use of these heterocycles in the development of a new four-component synthesis of biologically important α ...
Mumford, Peter Marten
core  

The role of beta-carbolines (harman/norharman) in heroin addicts

, 1995
SummaryEndogenous substances resulting from interactions between alcohol and possibly opioid metabolites and neurotransmitters (dopamine, indolamines) could be mediators of the pathochemical process towards dependence.
D Ladewig, R Stohler, H Rommelspacher
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Pd(II)-catalyzed C–H annulation and lactonization of indole-2-carboxamides with hydroxyalkynoates using air as an oxidant

Tetrahedron Chem
A novel palladium(II) catalyzed C–H annulation strategy has been developed for the synthesis of a diverse range of furo[3′,4':5,6]pyrido[3,4-b]indole-1,5(3H)-dione scaffolds. This is the first report on the construction of polycyclic carboline frameworks
Kiran Aswale, Rajashaker Bantu, B. Sridhar, B.V. Subba Reddy   +3 more
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Synthesis of 1,4‐Disubstituted and 1‐Substituted β‐Carbolines via 3‐Substituted 2‐Acylindoles [PDF]

β-Carbolines represent a large class of bioactive natural products, whereby most of these alkaloids bear residues at C1, and occasionally at C3, and only limited examples of 1,4-disubstituted β-carbolines are known.
Untergehrer, Martin, Jourjine, Ilya A. P., Bracher, Franz, Thees, Katharina   +3 more
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A Unified Strategy for the Synthesis of β‑Carbolines, γ‑Carbolines, and Other Fused Azaheteroaromatics under Mild, Metal-Free Conditions

, 2018
An efficient, unified approach for the synthesis of β-carbolines, γ-carbolines, and other fused azaheteroaromatics has been realized under metal-free conditions, from propargylic amines and (hetero)­aromatic aldehydes.
Dilipkumar Uredi (5807741), Dilipkumar Uredi, Damoder Reddy Motati, E. Blake Watkins (1478842), Damoder Reddy Motati (5367206), E. Blake Watkins   +5 more
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Effects of harmane, norharmane and harmine on apomorphine-induced pecking behavior in chick

Journal of Mazandaran University of Medical Sciences, 2009
.(Received 3 January, 2009; Accepted 27 May, 2009)AbstractBackground and purpose: -carboline alkaloids, also known as harmala's alkaloids have a wide spectrum of pharmacological actions including a stimulatory action on release of dopamine and other ...
Davood Farzin, Elika Salimi
doaj