Results 31 to 40 of about 166,273 (278)

Efficacy of immune checkpoint inhibitor treatment for head and neck mucosal melanoma recurrence in patients treated with carbon‐ion radiotherapy

Cancer Reports, 2023
Carbon‐ion radiotherapy (C‐ion RT) is effective for head and neck mucosal melanoma (HN‐MM), including radioresistant mucosal melanoma. Melanoma also responds effectively to immune checkpoint inhibitors (ICIs).
A. Musha, N. Kubo, H. Kawamura, N. Okano, Hiro Sato, Kohei Okada, K. Tomizawa, Norichika Ota, A. Adachi, M. Shino, O. Nikkuni, Shota Ida, K. Shirai, J. Saitoh, S. Yokoo, K. Chikamatsu, T. Ohno   +16 more
semanticscholar   +1 more source

Carbon ion radiotherapy as definitive treatment in non-metastasized pancreatic cancer: study protocol of the prospective phase II PACK-study

BMC Cancer, 2020
Background Radiotherapy is known to improve local tumor control in locally advanced pancreatic cancer (LAPC), although there is a lack of convincing data on a potential overall survival benefit of chemoradiotherapy over chemotherapy alone.
Jakob Liermann, Patrick Naumann, Adriane Hommertgen, Moritz Pohl, Meinhard Kieser, Juergen Debus, Klaus Herfarth   +6 more
doaj   +1 more source

Dose–volume constraints for head‐and‐neck cancer in carbon ion radiotherapy: A literature review

Cancer Medicine, 2023
Carbon ion radiotherapy (CIRT) has been applied in cancer treatment for over 25 years. However, guidelines for dose–volume constraints have not been established yet.
Maria Varnava, A. Musha, M. Tashiro, N. Kubo, N. Okano, H. Kawamura, T. Ohno   +6 more
semanticscholar   +1 more source

A comparison of carbon ion radiotherapy and transarterial chemoembolization treatment outcomes for single hepatocellular carcinoma: a propensity score matching study

Radiation Oncology, 2019
Background We compared clinical outcomes of carbon ion radiotherapy and transarterial chemoembolization in the treatment of hepatocellular carcinoma. Methods Data of 477 patients with hepatocellular carcinoma who had undergone carbon ion radiotherapy or ...
Shintaro Shiba, Kei Shibuya, Hiroyuki Katoh, Takuya Kaminuma, Masaya Miyazaki, Satoru Kakizaki, Ken Shirabe, Tatsuya Ohno, Takashi Nakano   +8 more
doaj   +1 more source

METTL3‐mediated m6A mRNA contributes to the resistance of carbon‐ion radiotherapy in non‐small‐cell lung cancer

Cancer Science, 2022
Lung cancer is one of the leading causes of death among cancer patients worldwide. Carbon‐ion radiotherapy is a radical nonsurgical treatment with high local control rates and no serious adverse events. N6‐methyladenosine (m6A) modification is one of the
Xiaofeng Xu, Peiru Zhang, Yangle Huang, W. Shi, J. Mao, N. Ma, L. Kong, Lin Guo, Jin-long Liu, Jian Chen, R. Lu   +10 more
semanticscholar   +1 more source

Difference in Acquired Radioresistance Induction Between Repeated Photon and Particle Irradiation

Frontiers in Oncology, 2019
In recent years, advanced radiation therapy techniques, including stereotactic body radiotherapy and carbon–ion radiotherapy, have progressed to such an extent that certain types of cancer can be treated with radiotherapy alone.
Katsutoshi Sato, Takashi Shimokawa, Takashi Imai   +2 more
doaj   +1 more source

A randomized controlled phase III study comparing hadrontherapy with carbon ions versus conventional radiotherapy – including photon and proton therapy – for the treatment of radioresistant tumors: the ETOILE trial

BMC Cancer, 2022
Background Some cancers such as sarcomas (bone and soft tissue sarcomas) and adenoid cystic carcinomas are considered as radioresistant to low linear energy transfer radiation (including photons and protons) and may therefore beneficiate from a carbon ...
Jacques Balosso, Olivia Febvey-Combes, Annie Iung, Hélène Lozano, Abdoulkader Soumai Alloh, Catherine Cornu, Magali Hervé, Zohra Akkal, Michel Lièvre, Valérie Plattner, Francesca Valvo, Cristina Bono, Maria Rosaria Fiore, Viviana Vitolo, Barbara Vischioni, Stéphanie Patin, Hubert Allemand, François Gueyffier, Jennifer Margier, Pascale Guerre, Sylvie Chabaud, Roberto Orecchia, Pascal Pommier   +22 more
doaj   +1 more source

Effectiveness of Carbon Ion Radiation in Locally Advanced Pancreatic Cancer

Frontiers in Oncology, 2021
PurposeEffective treatment strategies for unresectable locally advanced pancreatic cancer (LAPC) patients are eagerly warranted. Recently, convincing oncological outcomes were demonstrated by carbon ion radiotherapy.
Jakob Liermann, Jakob Liermann, Jakob Liermann, Jakob Liermann, Jakob Liermann, Patrick Naumann, Patrick Naumann, Patrick Naumann, Fabian Weykamp, Fabian Weykamp, Fabian Weykamp, Philipp Hoegen, Philipp Hoegen, Philipp Hoegen, Philipp Hoegen, Juergen Debus, Juergen Debus, Juergen Debus, Juergen Debus, Juergen Debus, Juergen Debus, Klaus Herfarth, Klaus Herfarth, Klaus Herfarth, Klaus Herfarth, Klaus Herfarth, Klaus Herfarth   +26 more
doaj   +1 more source

Carbon ion radiotherapy for inoperable pediatric osteosarcoma [PDF]

Oncotarget, 2018
Unresectable pediatric osteosarcoma has poor outcomes with conventional treatments.Twenty-six patients aged 11-20 years (median 16) had inoperable osteosarcoma of the trunk (24 pelvic, 1 mediastinal and 1 paravertebral) without any other lesion at initial examination. There were 22 primary, 1 locally recurrent and 3 metastatic cases.
Mohamad, Osama, Imai, Reiko, Kamada, Tadashi, Nitta, Yuki, Araki, Nobuhito   +4 more
openaire   +2 more sources

Fluorodeoxyglucose positron emission tomography (FDG/PET) shows the effect of carbon-ion radiotherapy (CIRT); with pathologic confirmation

Radiology Case Reports, 2023
Response evaluation of carbon-ion radiotherapy poses a diagnostic challenge. Due to its functional aspects, fluorodeoxyglucose positron emission tomography (FDG/PET) has a role in the diagnosis of photon radiation therapy.
Jun Aoki, MD, Yayoi Yamamoto, MD,PhD, Ayumi Horikawa, MD,PhD, Tsunehiro Doiuchi, MD, Ayako Hino, MD,PhD, Daichi Kojima, MD, Hiroaki Kurihara, MD,PhD, Kota Washimi, MD,PhD, Hiroyuki Katoh, MD,PhD, Toru Hiruma, MD,PhD   +9 more
doaj   +1 more source