Results 1 to 10 of about 978 (138)

Fluorodeoxyglucose positron emission tomography (FDG/PET) shows the effect of carbon-ion radiotherapy (CIRT); with pathologic confirmation [PDF]

Radiology Case Reports, 2023
Response evaluation of carbon-ion radiotherapy poses a diagnostic challenge. Due to its functional aspects, fluorodeoxyglucose positron emission tomography (FDG/PET) has a role in the diagnosis of photon radiation therapy. In addition, several studies suggested that FDG/PET may be useful to select the optimal site for performing a diagnostic biopsy ...
Yayoi Yamamoto, Hiroyuki Katoh, Ayako Hino-Shishikura   +2 more
exaly   +5 more sources

Accelerated Hypofractionated Active Raster-Scanned Carbon Ion Radiotherapy (CIRT) for Laryngeal Malignancies: Feasibility and Safety [PDF]

Cancers, 2018
(1) Background: The authors present the first results of active raster-scanned carbon ion radiotherapy (CIRT) for radioresistant laryngeal malignancies regarding efficacy and toxicity. (2) Methods: 15 patients with laryngeal adenoid cystic carcinoma (ACC; n = 8; 53.3%) or chondrosarcoma (CS; n = 7; 46.7%) who underwent radiotherapy with carbon ions ...
Sati Akbaba, Sebastian Adeberg, Alexandra Jensen   +2 more
exaly   +6 more sources

Adverse Events After Carbon-Ion Radiotherapy (CIRT) for Hepatocellular Carcinoma and Risk Factors for Biliary Stricture After CIRT: A Retrospective Study [PDF]

Cancers
Background/Objectives: This study investigated the timing of adverse events (AEs) after carbon-ion radiotherapy (CIRT) for hepatocellular carcinoma (HCC) and identified the risk factors for biliary stricture post CIRT. Methods: This retrospective study included 103 patients with HCC who had undergone CIRT (60 Gy/4 fractions).
Yoshiyuki Ueno, Hiroaki Haga, Tomohiro Katsumi   +2 more
exaly   +4 more sources

The sensitivity of radiobiological models in carbon ion radiotherapy (CIRT) and its consequences on the clinical treatment plan: Differences between LEM and MKM models [PDF]

Journal of Applied Clinical Medical Physics
AbstractPurposeCarbon ion radiotherapy (CIRT) relies on relative biological effectiveness (RBE)‐weighted dose calculations. Japanese clinics predominantly use the microdosimetric kinetic model (MKM), while European centers utilize the local effect model (LEM).
Góra J, Grosshagauer S, Fossati P, Mumot M, Stock M, Schafasand M, Carlino A.   +6 more
exaly   +4 more sources

Carbon-ion Radiotherapy for Colorectal Cancer

Journal of the Anus, Rectum and Colon, 2021
Heavy-ion radiotherapy (RT) is a kind of particle RT, and carbon-ion beam constitutes the primary delivery method of heavy-ion RT. Unlike the conventional photon modalities, particle RT, in particular carbon-ion radiotherapy (CIRT), offers unique ...
Shigeru Yamada, Hirotoshi Takiyama, Yuka Isozaki, Makoto Shinoto, Hirokazu Makishima, Naoyoshi Yamamoto, Hiroshi Tsuji   +6 more
doaj   +3 more sources

Carbon ion radiotherapy and radiation-induced lung injury: clinical evidence, mechanistic insights, and future directions [PDF]

Frontiers in Oncology
Carbon ion radiotherapy (CIRT), owing to its unique physical dose distribution and high linear energy transfer (high-LET) characteristics, has shown remarkable advantages in the treatment of thoracic tumors in recent years.
Yiqin Qiu, Guoqiang Zhong, Yongzhen Li, Wei Feng, Wei Feng, Wei Feng   +5 more
doaj   +2 more sources

Combined carbon ion radiotherapy and immunotherapy: leveraging the immunological advantages of carbon ion [PDF]

Frontiers in Immunology
Immunotherapy represents a systemic approach to cancer treatment; however, its effectiveness can be limited by intrinsic tumor resistance or immunosuppressive mechanisms within the tumor microenvironment.
Ruiming Chen, Qinqin Ma, Yuan Pan, Tanglong Zhang, Zhuoya Zhang, Cuixia Di, Juntao Ran   +6 more
doaj   +2 more sources

Surgical spacer placement prior carbon ion radiotherapy (CIRT): an effective feasible strategy to improve the treatment for sacral chordoma. [PDF]

World J Surg Oncol, 2016
Sacral chordoma (SC) is a neoplasm arising from residual notochordal cells degeneration. SC is difficult to manage mainly because of anatomic location and tendency to extensive spread. Carbon ion radiotherapy (CIRT) is highly precise to selectively deliver high biological effective dose to the tumor target sparing the anatomical structure on its path ...
Lorenzo C, Andrea P, Barbara V, Denis P, Rosaria FM, Piero F, Viviana V, Alberto I, Mario C, Brugnatelli S, Tommaso D, Bugada D, Marcello M, Mario A, Francesca V, Roberto O, Paolo D.   +16 more
europepmc   +5 more sources

Value of carbon-ion radiotherapy for early stage non-small cell lung cancer

Clinical and Translational Radiation Oncology, 2022
Carbon-ion radiotherapy (CIRT) is an important part of modern radiotherapy. Compared to conventional photon radiotherapy modalities, CIRT brings two major types of advantages to physical and biological aspects respectively.
Juan Xiong, Hanguang Ruan
doaj   +3 more sources

The rise of 3D spheroids in radiobiology for assessing tumour radioresistance [PDF]

Acta Oncologica
Background and purpose: Particle therapy (PT), including proton (PRT) and carbon ion radiotherapy (CIRT), offers physical and biological advantages over photon radiotherapy (XRT), particularly for radioresistant tumours such as glioblastoma and ...
Alexandra Charalampopoulou, Fabrizio De Luca, Giuseppe Magro, Niloufar Matoor, Amelia Barcellini, Giorgio Butella , Giovanni Battista Ivaldi , Sara Lillo, Lorenzo Manti, Alessio Mereghetti , Paola Tabarelli De Fatis , Maria Grazia Bottone , Angelica Facoetti   +12 more
doaj   +2 more sources