Results 61 to 70 of about 978 (138)

Development and dosimetric verification of static SHArc: Step‐and‐shoot carbon ion arc therapy for LETd escalation in pancreatic tumors

Medical Physics, Volume 52, Issue 10, October 2025.
Abstract Background Carbon ion radiotherapy (CIRT) offers higher linear energy transfer (LET) and superior relative biological effectiveness, making it a promising option for treating hypoxic, radioresistant tumors. Spot‐scanning Hadron Arc (SHArc) therapy enables dose‐averaged LET (LETd) escalation in the tumor but increases planning and setup ...
Filipa Baltazar, Thomas Tessonnier, Stewart Mein, Jakob Liermann, Abdallah Qubala, Jürgen Debus, Andrea Mairani   +6 more
wiley   +1 more source

Assessment of the impact of CT scan protocols on carbon ion radiotherapy treatment planning

Journal of Applied Clinical Medical Physics, Volume 26, Issue 9, September 2025.
Abstract Purpose The purpose of this study was to quantify the impact of computed tomography (CT) scan protocols and CT scanner on carbon ion radiotherapy treatment planning Material and Methods A table was created for each of the five parameters to relate CT values to stopping power (SPR) (CT‐SPR conversion table).
Yuya Miyasaka, Hikaru Souda, Yasuhito Hagiwara, Hiroko Akamatsu, Mayumi Harada, Takashi Kaneko, Hongbo Chai, Miyu Ishizawa, Hiraku Sato, Masashi Koto, Takeo Iwai   +10 more
wiley   +1 more source

Carbon‐Ion Radiation Therapy Compared to Surgical Resection for Primary, Solitary, Potentially Resectable Hepatocellular Carcinoma

JGH Open, Volume 9, Issue 9, September 2025.
ABSTRACT Aims Carbon‐ion radiation therapy (CIRT) is a promising technological innovation for treating hepatocellular carcinoma (HCC). This study aimed to evaluate the effectiveness and safety of CIRT for primary, solitary, potentially resectable HCC in comparison to liver resection (LR).
Soichiro Morinaga, Shinnosuke Kawahara, Rei Kanemoto, Naohiko Matsushita, Yuto Kamioka, Mariko Kamiya, Masaaki Murakawa, Taito Fukushima, Satoshi Kobayashi, Makoto Ueno, Hiroyuki Kato, Naoto Yamamoto   +11 more
wiley   +1 more source

A Novel Method for Prognostic Risk Classification After Carbon‐Ion Radiotherapy for Hepatocellular Carcinoma Using Data‐Mining Methods

Cancer Science, Volume 116, Issue 8, Page 2198-2207, August 2025.
First study to use decision tree analysis for predicting cancer‐specific survival after carbon‐ion radiotherapy for hepatocellular carcinoma. Decision tree model offers clear, patient‐friendly prognosis visualization. ABSTRACT No classification methods to predict prognosis after carbon‐ion radiotherapy for hepatocellular carcinoma have yet been ...
Kazuhiko Hayashi, Osamu Suzuki, Koji Ichise, Hirofumi Uchida, Makoto Anzai, Azusa Hasegawa, Shinichi Shimizu, Teruki Teshima, Jiro Fujimoto, Kazuhiko Ogawa   +9 more
wiley   +1 more source

Clinical application of high‐LET radiotherapy combined with immunotherapy in malignant tumors

Precision Radiation Oncology
The superior physical and biological properties of high linear energy transfer (LET), as opposed to traditional low‐LET rays, underscore the advantage of proton therapy (PRT) and carbon ion radiotherapy (CIRT) are better than traditional photon ...
Kexin Meng, Haijun Lu
doaj   +1 more source

Pencil Beam Scanning Carbon Ion Radiotherapy for Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2023
Wenna Zhang,1– 3 Xin Cai,1– 3 Jiayao Sun,2– 4 Weiwei Wang,2– 4 Jingfang Zhao,2– 4 Qing Zhang,1– 3 Guoliang Jiang,1– 3,5 Zheng Wang1– 3,5 1Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, People’s Republic of China ...
Zhang W, Cai X, Sun J, Wang W, Zhao J, Zhang Q, Jiang G, Wang Z   +7 more
doaj  

A step towards international prospective trials in carbon ion radiotherapy: investigation of factors influencing dose distribution in the facilities in operation based on a case of skull base chordoma

Radiation Oncology, 2019
Background Carbon ion radiotherapy (CIRT) has been delivered to more than 20,000 patients worldwide. International trials have been recommended in order to emphasize the actual benefits.
G. Vogin, A. Wambersie, M. Koto, T. Ohno, M. Uhl, P. Fossati, J. Balosso, on behalf of ULICE WP2 working group   +7 more
doaj   +1 more source

Clinical indications and future directions of carbon-ion radiotherapy: a narrative review

The Ewha Medical Journal
Carbon-ion radiotherapy (CIRT) offers superior dose distributions and greater biological effectiveness than conventional photon-based radiotherapy (RT).
Seo Hee Choi, Woong Sub Koom, Hong In Yoon, Kyung Hwan Kim, Chan Woo Wee, Jaeho Cho, Yong Bae Kim, Ki Chang Keum, Ik Jae Lee   +8 more
doaj   +1 more source

Prognostic analysis of radiation pneumonitis: carbon-ion radiotherapy in patients with locally advanced lung cancer

Radiation Oncology, 2017
Background Carbon-ion radiotherapy (CIRT) is a promising treatment for locally advanced non-small-cell lung cancer, especially for patients with inoperable lung cancer.
Kazuhiko Hayashi, Naoyoshi Yamamoto, Masataka Karube, Mio Nakajima, Naruhiro Matsufuji, Hiroshi Tsuji, Kazuhiko Ogawa, Tadashi Kamada   +7 more
doaj   +1 more source

Relative Biological Effectiveness (RBE) for Development of Lung Fibrosis After Single Dose Carbon Ion Radiotherapy (CIRT) [PDF]

International Journal of Radiation Oncology*Biology*Physics, 2019
C. Zhou, M. Moustafa, Z. Zhou, B. Jones, S. Brons, C. Schwager, M. Kriegsmann, F. Lasitschka, J. Debus, A. Abdollahi   +9 more
openaire   +1 more source