Results 51 to 60 of about 978 (138)

Assessment of the Validity of Carbon Ion Irradiation for C6 Gliomas in Rats

Dose-Response
Purpose Application of energy-spectrum computed tomography (CT) to assess specific efficacy of and response to carbon ion radiotherapy (CIRT) of C6 gliomas in rats.
Yufeng Li, Lei Ta, QingFeng Wu, Hongyu Zhang, Yuan Xu, Lu Gan, Jianli Liu   +6 more
doaj   +1 more source

Quantifying upright positioning accuracy with optical surface tracking in radiotherapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 3, March 2026.
Abstract Purpose This study quantified inter‐ and intra‐fractional setup accuracies in the upright posture and compared them among setups with different immobilization methods. Methods Two and four setups were examined for abdominal and head and neck (HN) cancer treatments, respectively.
Yusuke Nomura, Sodai Tanaka, Hideyuki Takei, Kinji Maeda, Takuro Takekoshi, Hideki Iwakami, Hirotoshi Takiyama, Minoru Tajiri, Shunsuke Yonai, Hideyuki Mizuno, Yoshiyuki Iwata, Taku Inaniwa, Hitoshi Ishikawa   +12 more
wiley   +1 more source

Upright and supine particle therapy of lung cancer: A 4D dosimetric comparison

Medical Physics, Volume 53, Issue 3, March 2026.
Abstract Background A renewed interest in upright particle therapy is currently driven by the availability of upright positioning and imaging systems. The upright positioning system could enhance fixed beamlines for effective carbon ion treatments in central body regions, with a substantial cost and space advantage.
Maria Chiara Martire, Lennart Volz, Marco Durante, Mark Pankuch, Christian Graeff   +4 more
wiley   +1 more source

Commissioning and robustness evaluation of external laser sensor for respiratory gating in carbon‐ion radiotherapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 1, January 2026.
Abstract Background Respiratory‐induced tumor motion remains a significant challenge in carbon‐ion radiotherapy (CIRT), potentially compromising dose accuracy and escalating dose in nearby organs. Although belt‐based sensors are commonly used for gating, issues related to setup reproducibility and patient comfort increased the demand for laser‐based ...
Tae‐Ho Kim, Soorim Han, Dohyeon Yoo, Sangmin Lee, Taegeon Oh, Dongjoon Lee, Changhwan Kim, Min Cheol Han, Chae‐Seon Hong, Jin Sung Kim   +9 more
wiley   +1 more source

Carbon ion irradiation mobilizes antitumor immunity: from concept to the clinic

Radiation Oncology
Carbon ion radiotherapy (CIRT), a type of particle therapy, is at the forefront of clinical oncology treatments due to its superior physical properties and biological performance.
Shanghai Liu, Xiangyang He, Siqi Liang, Anqing Wu, Lu Liu, Wentao Hu   +5 more
doaj   +1 more source

Ways to unravel the clinical potential of carbon ions for head and neck cancer reirradiation: dosimetric comparison and local failure pattern analysis as part of the prospective randomized CARE trial

Radiation Oncology, 2022
Background Carbon ion radiotherapy (CIRT) yields biophysical advantages compared to photons but randomized studies for the reirradiation setting are pending. The aim of the current project was to evaluate potential clinical benefits and drawbacks of CIRT
Thomas Held, Thomas Tessonnier, Henrik Franke, Sebastian Regnery, Lukas Bauer, Katharina Weusthof, Semi Harrabi, Klaus Herfarth, Andrea Mairani, Jürgen Debus, Sebastian Adeberg   +10 more
doaj   +1 more source

Microstructural profiling and habitat analysis to characterize treatment outcome patterns in Sacral Chordomas treated with carbon ions

Medical Physics, Volume 53, Issue 1, January 2026.
Abstract Background Sacral chordoma (SC) is a rare and locally aggressive tumor, characterized by a high risk of local recurrence (LR). Advanced imaging biomarkers capturing tumor heterogeneity and treatment response may help refine patient stratification and improve outcomes.
Letizia Morelli, Giovanni Parrella, Marco Rotondi, Silvia Molinelli, Giuseppe Magro, Sara Imparato, Agnieszka Chalaszczyk, Maria Rosaria Fiore, Chiara Paganelli, Ester Orlandi, Guido Baroni   +10 more
wiley   +1 more source

Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review

Rare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu, Ding‐Hu Zhang, Chuan Hu, Yi‐Nan Ding, Kun Chen, Yi Jiang, Jun Luo, Fei Cao, Wei‐Yuan Hao, Bin‐Yan Zhong, Jie Lin, Dong Xu, Jia‐Ping Zheng   +12 more
wiley   +1 more source

Determining RBE for development of lung fibrosis induced by fractionated irradiation with carbon ions utilizing fibrosis index and high-LET BED model

Clinical and Translational Radiation Oncology, 2019
Background and purposes: Carbon ion radiotherapy (CIRT) with raster scanning technology is a promising treatment for lung cancer and thoracic malignancies.
Cheng Zhou, Bleddyn Jones, Mahmoud Moustafa, Bing Yang, Stephan Brons, Liji Cao, Ying Dai, Christian Schwager, Ming Chen, Oliver Jaekel, Longhua Chen, Juergen Debus, Amir Abdollahi   +12 more
doaj   +1 more source

Successful Management of Advanced Olfactory Esthesioneuroblastoma: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Early imaging and biopsy are crucial for diagnosing esthesioneuroblastoma. Multimodal treatment—endoscopic or combined surgery, adjuvant radiotherapy, and selective chemotherapy—offers the best outcomes. Long‐term follow‐up is essential to detect recurrences and manage complications like optic neuritis. Multidisciplinary coordination optimizes
Chiraz Halwani, Sana Ferchichi, Mariem Messelmani   +2 more
wiley   +1 more source