Results 121 to 130 of about 11,242 (227)

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Carbon-ion radiotherapy in accelerated hypofractionated active raster-scanning technique for malignant lacrimal gland tumors: feasibility and safety

Cancer Management and Research, 2019
Sati Akbaba,1–3 Kristin Lang,1,2 Thomas Held,1,2 Klaus Herfarth,1–3 Juliane Rieber,1–3 Peter Plinkert,4 Gerd U Auffarth,5 Stefan Rieken,1–3 Juergen Debus,1–3 Sebastian Adeberg1–3 1Department of Radiation Oncology ...
Akbaba S, Lang K, Held T, Herfarth K, Rieber J, Plinkert P, Auffarth GU, Rieken S, Debus J, Adeberg S   +9 more
doaj  

Predicting Poor Efficacy of Cabozantinib in Advanced Renal Cell Carcinoma by Exploratory Metabolic Pathway Analysis and In Vitro Verification

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Cabozantinib (CABO) is currently an essential drug for first‐line and sequential therapy in the treatment of advanced renal cell carcinoma (RCC). Predicting its therapeutic efficacy will enable efficient drug selection and improve the prognosis of patients.
Takanari Sakai, Yoshihide Kawasaki, Izumi Sakamoto, Eiji Hishinuma, Naomi Matsukawa, Daigo Chiba, Tomonori Sato, Kento Morozumi, Masamitsu Maekawa, Nariyasu Mano, Akihiro Ito   +10 more
wiley   +1 more source

Advances in radiotherapy for mouth neoplasms: emerging technologies and future perspectives

Discover Oncology
Oral cancer is a common malignant tumor of the head and neck region, significantly impacting human health and quality of life. Radiotherapy has become an essential component of treatment, often used in combination with surgery and/or chemotherapy ...
Xuhong Liu, Zhuoya Zhang, Xinyu Deng, Zekun Lang, Jianrong Wang   +4 more
doaj   +1 more source

Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation Therapy

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal, Caden M. Fritson, Alexandra Seas, Heidi Vieira, Surinder K. Batra   +4 more
wiley   +1 more source

Effects of ketogenic and low‐carbohydrate diet on glucose and weight control in type 2 diabetes mellitus patients along with metabolome change

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Both the low‐carbohydrate diet (LCD) and the ketogenic diet (KD) positively affect body weight and glucose metabolism in type 2 diabetes. Metabolomic signatures sensitively reflect each diet and correlate with clinical improvements – distinct metabolite associations with glycated haemoglobin and weight were identified for LCD versus KD.
Yao Wang, Haozhe He, Zhenjing Lyu, Yeyang Wang, Li Chen, Junbin Liang, Cong Lin, Huanhuan Wang, Shiping Zhang, Gugen Xu, Junzhang Tian, Kejing Zeng   +11 more
wiley   +1 more source

Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu, Yu Su, Li Zhou, Jianzhou Liu, Junchao Guo   +4 more
wiley   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, Volume 11, Issue 4, Page 1095-1110, August 2026.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Industrial Hydrocarbons Exposure Deteriorates Sperm Integrity and Reproductive Function

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
ABSTRACT Occupational exposure to polycyclic aromatic hydrocarbons (PAHs) or metal fumes in the workplace may be detrimental to male fertility. The present study compared sperm concentration, total motility, strict morphology and oxidative stress and SDF levels between 81 men, controls (n = 17) and workers from plastic industry workers (n = 18), steel ...
Madhan Kumar Pichandi, Babujanarthanam Ranganathanan, Doraiah Abilash   +2 more
wiley   +1 more source

Carbon ion radiotherapy in NIRS

Carbon ion radiotherapy in NIRS
High linear energy transfer (LET) charged particle therapy with carbon ions has been of interest in the treatment of malignant tumors because of better dose localization in the tumor volume and greater biologic effectiveness. In 1984, the Heavy Ion Medical Accelerator in Chiba (HIMAC) was constructed at the National Institute of Radiological Sciences ...
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