Metal‐Based Materials for Redox Modulation in Biomedicine
ABSTRACT Metal materials have become increasingly important in modulating biological redox networks for therapeutic and diagnostic purposes, owing to their distinctive electronic properties and adaptable reactivity. This review synthesizes recent developments across various metal‐based materials, including elemental metals, metal oxides, coordination ...
Yan Fan +7 more
wiley +1 more source
Comparative 30‐day life cycle assessment of bladder drainage strategies
Objective To identify the most environmentally sustainable urinary drainage strategies commonly used to manage bladder outlet obstruction and also to highlight actionable levers for reducing the footprint of urinary drainage in clinical practice. Materials and Methods We conducted a comparative life cycle assessment of three urinary drainage strategies
Arthur Peyrottes +11 more
wiley +1 more source
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source
Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari +6 more
wiley +1 more source
ABSTRACT Myotonic dystrophy type 1 (DM1) is a progressive muscular disorder caused by the expansion of CTG repeats in the 3′ UTR of the DMPK gene. Although the pathogenic mechanisms remain unclear, recent evidence suggests that activation of innate immune responses may contribute to disease progression. In this study, we examined the ultrastructure and
Renata Del Carratore +8 more
wiley +1 more source
Carbon Ion Radiotherapy for Retroperitoneal Sarcoma: A Single-Institution Study. [PDF]
Imai R +6 more
europepmc +1 more source
Sultams as Dual Inhibitors of Human Carbonic Anhydrase and Thioredoxin Reductase
A series of sultam‐based N‐acyl derivatives with potential applications as dual TrxR1 and CA inhibitors were synthesized and evaluated. TrxR1 screening identified several active compounds, with inhibitory potency influenced by the type and orientation of substituents.
Aleksandrs Pustenko +8 more
wiley +1 more source
Application of intrahepatic fiducial markers in carbon ion radiotherapy for pancreatic cancer-Achieving higher precision treatment. [PDF]
Nagata J +9 more
europepmc +1 more source
Clinical outcomes of carbon-ion radiotherapy for residual or recurrent hepatocellular carcinoma after transarterial chemoembolization. [PDF]
Sekiguchi Y +8 more
europepmc +1 more source
Exploratory case series of conversion to carbon ion radiotherapy after systemic therapy in advanced hepatocellular carcinoma. [PDF]
Anzai H +23 more
europepmc +1 more source

