Results 131 to 140 of about 3,400,908 (256)

Vision and implementation for the first U.S. carbon ion therapy center part II: Design philosophy and clinical implementation

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract The anticipated clinical demand for carbon ion radiotherapy (CIRT) in the United States is expected to include a substantial proportion of clinically complex disease sites that require accurate, highly conformal, and adaptive treatment. These clinical needs, together with the unique physical and biological characteristics of carbon ion beams ...
Xiaoying Liang, Chris J Beltran
wiley   +1 more source

Overview of carbon ion radiotherapy

Overview of carbon ion radiotherapy
In cancer radiotherapy (RT), ion beams such as proton and carbon ion beams have unique characteristics of improved dose distributions, enabling a delivery of sufficient dose to the target volume while minimizing the dose in the surrounding normal tissues. In addition, carbon ions being heavier than protons provide a higher biological effectiveness with
openaire   +3 more sources

Dynamic Proton arc therapy for paediatric parameningeal rhabdomyosarcoma

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Background Parameningeal rhabdomyosarcomas (PM‐RMS) are pediatric tumors with a high risk of local failure and severe toxicity. Intensity modulated proton therapy (IMPT) offers improved healthy tissue sparing compared to conventional photon‐based radiotherapy, and proton arc therapy (PAT) might offer further improvement in healthy tissue ...
Andreas Havsgård Handeland, Hardev Singh Grewal, Camilla Grindeland Boer, Daniel J. Indelicato, Kristian Smeland Ytre‐Hauge, Helge Henjum, Camilla Hanquist Stokkevåg   +6 more
wiley   +1 more source

Vision and implementation for the first U.S. carbon ion therapy center part I: Clinical rationale and the need for CIRT in the United States

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Carbon ion radiotherapy (CIRT) has evolved into an established clinical modality over the past three decades. Owing to its unique physical and biological characteristics, CIRT has demonstrated favorable outcomes for selected malignancies characterized by radioresistance, proximity to critical organs, locally advanced disease requiring safe ...
Xiaoying Liang, Chris J Beltran
wiley   +1 more source

First prospective feasibility study of Carbon-Ion radiotherapy using compact superconducting rotating gantry.

We had developed compact rotating gantry for carbon ion using superconducting magnets in 2015 which became clinically operational on 2017. The objective of this study was to assess the clinical feasibility and safety of using compact rotating gantry with
1001610, 1001612, 1001611, Kasuya, Goro, Hagiwara, Yasuhito, 1001618, 1001617, Goro, Kasuya, 1001619, Koto, Masashi, 1001614, Makishima, Hirokazu, 1001613, Yasuhito, Hagiwara, Masashi, Koto, 1001616, 1001615, Tadashi, Kamada, Bhattacharyya, Tapesh, Ikawa, Hiroaki, 1001620, 1001601, Hirokazu, Makishima, Hiroaki, Ikawa, Hiroshi, Tsuji, 1001607, Yamamoto, Naoyoshi, 1001606, 1001609, Kazuhiko, Hayashi, 1001608, 1001603, Hayashi, Kazuhiko, 1001602, 1001605, 1001604, Naoyoshi, Yamamoto, Kamada, Tadashi, Tsuji, Hiroshi   +38 more
core  

Impact of robust optimization and beam configuration on the distribution stability of LET under delivery uncertainties in carbon‐ion therapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.
Abstract Background Carbon‐ion radiotherapy exploits high linear energy transfer (LET) to enhance biological effectiveness, and low dose‐averaged LET (LETd) within the target volume is associated with local recurrence in pancreatic cancer. Although robust optimization is widely used to improve dose robustness against delivery uncertainties, systematic ...
Wisawa Phongprapun, Mutsumi Tashiro
wiley   +1 more source

ABSTRACTS

Precision Radiation Oncology, EarlyView.
wiley   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, Volume 13, Issue 61, 3 November 2026.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Carbon-ion radiotherapy in accelerated hypofractionated active raster-scanning technique for malignant lacrimal gland tumors: feasibility and safety

Cancer Management and Research, 2019
Sati Akbaba,1–3 Kristin Lang,1,2 Thomas Held,1,2 Klaus Herfarth,1–3 Juliane Rieber,1–3 Peter Plinkert,4 Gerd U Auffarth,5 Stefan Rieken,1–3 Juergen Debus,1–3 Sebastian Adeberg1–3 1Department of Radiation Oncology ...
Akbaba S, Lang K, Held T, Herfarth K, Rieber J, Plinkert P, Auffarth GU, Rieken S, Debus J, Adeberg S   +9 more
doaj  

Advances in radiotherapy for mouth neoplasms: emerging technologies and future perspectives

Discover Oncology
Oral cancer is a common malignant tumor of the head and neck region, significantly impacting human health and quality of life. Radiotherapy has become an essential component of treatment, often used in combination with surgery and/or chemotherapy ...
Xuhong Liu, Zhuoya Zhang, Xinyu Deng, Zekun Lang, Jianrong Wang   +4 more
doaj   +1 more source