Results 61 to 70 of about 25,186 (207)

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

open access: yesThe FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz   +13 more
wiley   +1 more source

Carbohydrate Physicochemical Properties: The Innate Hydrogen Bond Donating Capacities of α‐Glucoside and α‐Galactoside Alcohol Groups

open access: yesAngewandte Chemie, Volume 138, Issue 34, 17 August 2026.
Experimental determination of the innate hydrogen bond donating capacities of the glucose and galactose non‐anomeric alcohols revealed significant variations depending on position and relative configuration, which were quantified on the pKAHY scale, relevant for MedChem purposes, hence providing another tool toward rational glycomimetic development ...
Mrinal Naskar   +8 more
wiley   +2 more sources

The effect of Devivit Carnitine on the functional state of the liver in rats under experimental carbon tetrachloride intoxication

open access: yesUkrainian Journal of Veterinary and Agricultural Sciences
The liver is a key organ responsible for maintaining homeostasis, detoxification, and metabolic balance. Among the models of experimental liver pathology, carbon tetrachloride intoxication is widely used, as it is associated with the intensive generation
U. M. Vus, B. V. Gutyj
doaj   +1 more source

Recombinant ADAMTS13 Ameliorates Liver Injury and Improves Hepatic Microcirculation in a Murine Acute‐on‐Chronic Liver Failure Model

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim The therapeutic significance of recombinant a disintegrin‐like and metalloprotease with thrombospondin type 1 motif 13 (rADAMTS13) in acute‐on‐chronic liver failure (ACLF) remains unclear. We aimed to investigate the therapeutic effects of rADAMTS13 in a murine model of ACLF‐like liver injury.
Jun‐ichi Hanatani   +9 more
wiley   +1 more source

CD68 and F4/80 Markers Demonstrate Inflammatory Synergism Between Apical Periodontitis and Liver Fibrosis in Wistar Rats

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim To evaluate CD68 and F4/80 glycoproteins in the worsening of apical periodontitis (AP) and liver fibrosis (LF) in Wistar rats. Methodology Thirty‐two Wistar rats were distributed in the following groups (n = 8): C—control; AP—apical periodontitis; LF—liver fibrosis; APLF—AP and LF.
L. V. Barroti   +9 more
wiley   +1 more source

Removal of Real Vegetable Oil Industry Wastewater by Electrocoagulation and Electroflotation Methods

open access: yesWater and Environment Journal, EarlyView.
This study investigated the effective treatment of real vegetable oil industry wastewater with high pollutant content using electrocoagulation and electroflotation processes with SS316 mesh electrodes. ABSTRACT This study investigated the applicability of environmentally friendly technologies for treating vegetable oil industry wastewater containing ...
Talip Turna, Yalçın Şevki Yıldız
wiley   +1 more source

Effect of aqueous extract of Broccoli plant on liver enzymes in laboratory animals treated by carbon tetrachloride

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2014
The effects of aqueous extracts of broccoli plant against liver enzymes (ALP, ALT,AST,GST) in the laboratory animals treated with carbon tetrachloride were studied.
Iqbal Fadhel Alwan   +2 more
doaj   +1 more source

Schiff Base‐UiO66 Composite‐based Dispersive Micro Solid‐Phase Extraction of Pesticides From Fruit Juices Combined With Dispersive Liquid‐Liquid Microextraction Prior to Gas Chromatography‐Flame Ionisation Detection

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT A dispersive micro solid‐phase extraction method was introduced using a Schiff base‐UiO66 nanocomposite as the adsorbent in the extraction of multi‐class pesticide residues in pear, cherry, grape, and apricot juices. The extraction procedure was hyphenated with a liquid‐phase microextraction procedure, providing a high preconcentration factor ...
Behnam Hosseininezhad   +5 more
wiley   +1 more source

Protective Effect of the Persian Gulf brittle star Ophiocoma Erinaceus extract on carbon tetrachloride (CCl4) induced liver damage in adult male Wistar rats

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2015
Background and Aim:  Brittle star possess  bioactive compounds which confer the wound healing capacity and regenerative potency of damaged  arms and organisms to this creature.
Aida Soheili   +4 more
doaj  

Diagnostic potential of B‐cell translocation gene 2 in IgA nephropathy: Insights from molecular mechanisms

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Diagnostic value of BTG2 and its immunoregulatory mechanism in IgAN. This study reveals that BTG2 improves immune microenvironment dysregulation, attenuates inflammation, and reduces fibrosis by promoting the expansion of T follicular helper cells, inducing macrophage polarization toward an M2 anti‐inflammatory phenotype, and inhibiting the TGF‐β1 ...
Min Kou   +4 more
wiley   +1 more source

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