Results 71 to 80 of about 25,186 (207)

Report on the 13th international workshop on the CCN family of genes and inaugural ARBIOCOM conference, Nice, France

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Celebration of the 13th ICCNS meeting joint to the 1st ARBIOCOM Conference held on the site of Nice in December 2025. Abstract The 13th International Workshop on the CCN Family of Genes, held in Nice as part of the inaugural ARBIOCOM World Conference, brought together investigators with diverse research backgrounds, disciplines, and expertise. Building
Bernard Perbal   +3 more
wiley   +1 more source

Fisetin Attenuates Amyloid‐Beta‐Induced Neurotoxicity in Human Neuroblastoma SH‐SY5Y Cells: Integrating In Silico Target Prediction and In Vitro Validation

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The in‐silico data showed that fisetin binds stably with the autophagy receptors and synaptic density regulators. Further, in‐vitro data confirmed the restoration of Aβ1‐42 disrupted autophagy by fisetin. Fisetin restored the oxidative stress and ion channels, along with a reduction of AChE activity.
Charu Jaiswal   +2 more
wiley   +1 more source

Evaluation of Hepatoprotective Effects of Hydroalcoholic Extract of Green Pepper and Parsley on the Toxicity Induced by Carbon Tetrachloride in Rats

open access: yesArmaghane Danesh Bimonthly Journal, 2014
Background & aim: Green pepper and parsley have high antioxidant properties due to flavonoids and polyphenolic compounds. The aim of this study was to investigate the hepatoprotective effects of hydroalcoholic extract of green pepper and parsley on the
E Adibfard, A Mirzaei, T Pourelmi
doaj  

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 18, Page 5476-5495, September 2026.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth   +14 more
wiley   +1 more source

Self‐Reporting Diels–Alder Networks: Fluorescent Tracking of Reaction Conversion and Thermal History

open access: yesAggregate, Volume 7, Issue 8, August 2026.
This work demonstrates how to track the curing stage within end‐of‐life recyclable Diels‐Alder networks visually through fluorescence, by introducing a small amount of maleimide‐functionalized tetraphenylethylene. The thermochromic behavior is reversible, being particularly useful in self‐healing applications (often requiring local heating) and process
Paul van den Tempel   +6 more
wiley   +1 more source

Development of Solid Phase Microextraction for Determination of Carbon tetrachloride and Chloroform in Air by Gas Chromatography-Mass Spectrometry

open access: yesMuhandisī-i bihdāsht-i ḥirfah/ī, 2016
Introduction: In this research the solid phase micro extraction (SPME) for sampling and determination of carbon tetrachloride and chloroform in air was developed and effect of ambient parameters on SPME was assessed. Methods: For this purpose standard
hamad javad Zare Sakhvidi   +2 more
doaj  

Enabling Singlet Fission Exothermicity by Tuning the Solvent in a High Energy Triplet Formyl‐Fluorene Derivative

open access: yesChemPhotoChem, Volume 10, Issue 8, August 2026.
Solvent polarity/viscosity coupled with the concentration effect on the INTRA + INTERmolecular singlet fission of a formyl‐fluorene derivative are explored by ultrafast spectroscopy. Small changes in solvent dielectric constant/polarizability are very effective in modulating the S1‐1TT energy gap pointing to a slightly endothermic SF in toluene and ...
Roberto Cantoni   +4 more
wiley   +1 more source

ASGR1 Deficiency Promotes Liver Fibrosis by Enhancing Pro‐Inflammatory Arachidonic Acid Metabolism and ALP Secretion

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 8, August 2026.
ABSTRACT Background Asialoglycoprotein receptor 1 (ASGR1), a hepatocyte‐specific receptor, represents a potential therapeutic target for hypercholesterolemia. However, liver safety risks of ASGR1‐targeted therapies remain poorly characterized. This study aims to investigate the impact of ASGR1 deficency on liver fibrosis and its underlying mechanisms ...
Hui Zhu   +9 more
wiley   +1 more source

Small Extracellular Vesicle‐Derived Nidogen 1 Promotes HCC Carcinogenesis via Transglutaminase 3‐Mediated YAP/TAZ Signalling

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
NID1‐rich sEVs released by HCC cells are internalized by recipient cells, where the C‐terminal region of NID1 binds to and stabilizes TGM3. This activates integrin‐FAK/Src/AKT and Hippo‐YAP/TAZ signalling, thereby promoting HCC proliferation, colony formation, migration, invasion, tumour growth, and lung metastasis.
Cherlie Lot Sum Yeung   +9 more
wiley   +1 more source

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