Results 81 to 90 of about 35,100 (234)

A Solvent‐Free Synthesis of Imidazo[1,5‐a]pyridines Using CCl4 as an Oxidant

open access: yesJournal of Heterocyclic Chemistry, EarlyView.
A solvent‐free synthesis of imidazo[1,5‐a]pyridines (Impys) using CCl4 as an oxidant reagent and DBU as the base is informed. An array of Impys derived from different benzylic, heteroaryl aldehydes and others was synthesized in moderate to good yields.
Alejandro Castillo‐Baltazar   +5 more
wiley   +1 more source

Improved risk estimates for carbon tetrachloride. 1998 annual progress report

open access: yes, 1998
'The overall purpose of these studies is to improve the scientific basis for assessing the cancer risk associated with human exposure to carbon tetrachloride.
Springer, David L.   +2 more
core   +1 more source

Assessment of Carbon Tetrachloride Groundwater Transport in Support of the Hanford Carbon Tetrachloride Innovative Technology Demonstration Program [PDF]

open access: yes, 2001
Groundwater modeling was performed in support of the Hanford Carbon Tetrachloride Innovative Treatment Remediation Demonstration (ITRD) Program. The ITRD program is facilitated by Sandia National Laboratory for the Department of Energy Office of Science ...
Cameron, Richard J   +13 more
core   +1 more source

A multimodel intercomparison study of variable‐resolution global models with grid refinement over the Arctic and Antarctic

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
We document the protocol and first results from the first ever coordinated multimodel variable‐resolution experiment set with refinement over the polar regions. We find that the refinement generally yields model‐dependent effects. The most consistent improvement is an amelioration of the upper‐level cold bias in the polar regions that translates into ...
Lise Seland Graff   +8 more
wiley   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros   +5 more
wiley   +1 more source

A N,N′‐p‐Tolyl Substituted Diazadiene Ligand with a Dithienylethane Backbone in Hexacoordinated Group IV Tetrachlorido Complexes—Steric Repulsions Govern the Axial Chirality Mode

open access: yesZeitschrift für anorganische und allgemeine Chemie, EarlyView.
The chelating imino groups in [MCl4(DADDTEthane)] (M = Ti, Zr, Hf) give rise to a planar five‐membered (‐N=C‐C=N‐)M metallacycle. The two thiophene rings of the ligand backbone reside in a noncoplanar arrangement concerning the metallacycle, giving rise to two chiral C–C axes in the ligand backbone.
Dirk Schlüter   +3 more
wiley   +1 more source

Hepatoprotective effects of ethanol extract of Caesalpiniabonduc against carbon tetrachloride induced hepatotoxicity in Albino Rats

open access: yesJournal of Applied Sciences and Environmental Management, 2016
The present study was carried out to evaluate the Acute toxicity, hepatoprotective and in-vivo antioxidant activities of ethanolic extract of Caesalpinia bonduc leaf on carbon tetrachloride (CCl4) induced liver damage using Swiss albino rats .
A.E. Ubhenin   +3 more
doaj   +1 more source

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth   +14 more
wiley   +1 more source

A Negatively Curved Pyrene‐Fused Azaacene

open access: yesAngewandte Chemie, Volume 138, Issue 24, 8 June 2026.
A pyrene‐fused azaacene derivative is reported in which steric overcrowding caused by eight phenyl substituents induces bending of the aromatic framework rather than twisting. ABSTRACT Non‐planar aromatic hydrocarbons display distorted π‐frameworks that give rise to unique optoelectronic properties.
Marco Carini   +3 more
wiley   +2 more sources

Hepatocyte TrkB Acts as a Gatekeeper Against MASH‐Related Liver Fibrosis by Suppressing the TGFβ/CCL2 Axis and Macrophage Infiltration

open access: yesCell Proliferation, EarlyView.
Hepatocyte TrkB is identified as a critical gatekeeper against MASH‐related fibrosis. Mechanistically, TrkB inhibits the TGFβ/SMAD3/FOS axis to suppress CCL2 secretion, thereby blocking pathogenic macrophage recruitment and ameliorating liver fibrosis.
Yueying Chen   +11 more
wiley   +1 more source

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