Results 81 to 90 of about 25,186 (207)
Aim: The toxic chemical compounds are widelyused in the world. Carbon tetrachloride which is used in hygiene industries caused tissue disorders. Medicinal plants have protective effects in body tissues.
Z soleimani, N mirazi
doaj
A Solvent‐Free Synthesis of Imidazo[1,5‐a]pyridines Using CCl4 as an Oxidant
A solvent‐free synthesis of imidazo[1,5‐a]pyridines (Impys) using CCl4 as an oxidant reagent and DBU as the base is informed. An array of Impys derived from different benzylic, heteroaryl aldehydes and others was synthesized in moderate to good yields.
Alejandro Castillo‐Baltazar +5 more
wiley +1 more source
Decoding Akkermansia muciniphila Effector Biology: From Microbial Molecules to Host Outcomes
Schematic overview of the proposed gut–brain axis mechanisms linking Akkermansia muciniphila to host outcomes. A. muciniphila‐derived signals, including SCFAs and P9/GLP‐1‐related endocrine pathways, may influence epithelial barrier integrity, inflammatory responses, systemic immune signaling, and neural communication through the enteric nervous system,
Amir Arsalan Ghahari +9 more
wiley +1 more source
1. Resmetirom attenuates the activation of HSCs induced in in vitro and in vivo models. 2. Resmetirom attenuates the activation of HSCs through its specific action on the thyroid hormone receptor alpha. 3. Resmetirom requires fatty‐acid amide hydrolase 1 to reduce HSC activation. ABSTRACT Resmetirom is a liver‐directed, thyroid hormone receptor β (THRβ)
Eva Novoa +17 more
wiley +1 more source
Hg2+ is considered one of the most dangerous heavy metal pollutants. The fumed‐Si‐Pr‐TAP was prepared by functionalizing fumed‐silica with 3‐(chloropropyl)trimethoxysiliane and 2,4,6‐triaminopyrimidine (TAP). Fumed‐Si‐Pr‐TAP can detect Hg2+ ions in aqueous solutions with good sensitivity and selectivity.
Ghodsi Mohammadi Ziarani +6 more
wiley +1 more source
ABSTRACT Lithium–sulfur batteries have attracted extensive interest owing to their exceptionally high theoretical energy density and environmental benignity. However, their practical performance remains severely constrained by intrinsic challenges, including the polysulfide shuttle effect and large volume expansion during cycling, which markedly ...
Long Jiang +8 more
wiley +1 more source
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros +5 more
wiley +1 more source
Protective Effects of Selenopyran Against Carbon Tetrachloride Hepatotoxicity in Rats
Protective Effects of Selenopyran Against Carbon Tetrachloride Hepatotoxicity in ...
L. B. ZAVODNIK +7 more
doaj
Hepatocyte TrkB is identified as a critical gatekeeper against MASH‐related fibrosis. Mechanistically, TrkB inhibits the TGFβ/SMAD3/FOS axis to suppress CCL2 secretion, thereby blocking pathogenic macrophage recruitment and ameliorating liver fibrosis.
Yueying Chen +11 more
wiley +1 more source
This study explores the molecular mechanisms by which NaB ameliorates liver fibrosis from the perspectives of the gut–liver axis and metabolic reprogramming. In vivo and in vitro experiments demonstrate that gut‐derived NaB may alleviate liver injury and fibrosis by inhibiting hepatic stellate cell activation and aerobic glycolysis through the HDAC3/c ...
Yong Sun +8 more
wiley +1 more source

