Results 51 to 60 of about 25,186 (207)

Protective and Antioxidant ctivity of the Ethanol Extracts of Pleurotus Osteratus and Pleurotus Djamor on CCl4-induced Liver Injury in Rat

Journal of Medicinal Plants, 2016
Background: Hepatopathy induced from toxic chemicals and some drugs has harmful effects on the metabolism. Carbon tetrachloride (CCL4) able to make liver damage in humans and animals.
H Mobarak, F Niazpour, R Jaafari jozani
doaj  

The effect of milk thistle (Silybum marianum), methionine, tocopherol acetate, and ascorbic acid in a feed supplement on rats' morphological and biochemical blood parameters under carbon tetrachloride poisoning

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки
The article presents the research results on the feed supplement “Silimevit” effect on the morphological blood parameters and protein-synthesizing function of the liver in rats under carbon tetrachloride intoxication.
Ya. V. Lerchuk, A. K. Tkach, V. O. Kruk, B. V. Gutyj, I. I. Khariv, R. O. Vasiv, A. V. Vyniarska, N. M. Slobodiuk, T. V. Martyshuk, U. M. Vus, M. I. Shkil, Kh. Ya. Leskiv   +11 more
doaj   +1 more source

Melatonin protects the liver and erythrocytes against oxidative stress in cirrhotic rats Melatonina protege o fígado e eritrócitos do estresse oxidativo em ratos cirróticos

Arquivos de Gastroenterologia, 2010
CONTEXT: Cirrhosis is a progressive chronic hepatopathy which constitutes an irreversible stage of liver dysfunction. OBJECTIVES: To evaluate the oxidative stress in the blood of cirrhotic rats treated with the antioxidant melatonin.
Darlan Pase da Rosa, Silvia Bona, Douglas Simonetto, Claudio Zettler, Cláudio Augusto Marroni, Norma Possa Marroni   +5 more
doaj   +1 more source

Western Diet Combined With Chemical Induction: A Strategy for Rapid Development of MASLD Pathology in Mice

iNew Medicine, EarlyView.
ABSTRACT Objective The molecular mechanisms underlying the development of metabolic‐dysfunction‐associated steatotic liver disease (MASLD) are essential for developing appropriate treatments. The purpose of this study was to establish an MASLD model in mice with rapid and consistent progression.
Ting‐Ting Chen, Nan Li, Shuo Wang, Miao Sun, Rui Yang, Shi‐Hao Zhang, Xiao‐Lei Li, Chen Dong, Ke‐Yuan Chen, Wu‐Yi Sun, Na Zhou   +10 more
wiley   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Balancing Chain Transfer Agent Transport and Reaction in Emulsion Polymerization

Macromolecular Reaction Engineering, EarlyView.
The interrelationship between chain transfer agent mass transfer and reaction in emulsion polymerization is examined. Three parameters describing these phenomena are proposed. The probability of mass transfer‐ rather than reaction‐limitation for each CTA‐monomer pair is assessed.
F. Joseph Schork
wiley   +1 more source

Hepatoprotective effects of ethanol extract of Caesalpiniabonduc against carbon tetrachloride induced hepatotoxicity in Albino Rats

Journal of Applied Sciences and Environmental Management, 2016
The present study was carried out to evaluate the Acute toxicity, hepatoprotective and in-vivo antioxidant activities of ethanolic extract of Caesalpinia bonduc leaf on carbon tetrachloride (CCl4) induced liver damage using Swiss albino rats .
A.E. Ubhenin, I Igbe, F.A. Adamude, A Falodun   +3 more
doaj   +1 more source

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

Portal Hypertension &Cirrhosis, EarlyView.
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf, Mahboobeh Ebrahimi Varkiani, Saeid Abroun, Pedram Asadi‐Sarabi, Shukoofeh Torabi, Elham Rismani, Mohammad Majd Hammour, Andreas K. Nüssler, Massoud Vosough   +8 more
wiley   +1 more source

Protective Effects of Bee Venom (Apis mellifera) Against Cadmium‐Induced Hepatorenal Toxicity, Oxidative Stress, and Anxiety‐Like Behavior in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane, Chedli Ellijimi, Rym Elfessi, Ranya Hezzi, Khemaies Ben Rhouma, Hafedh Abdelmelek, Najet Srairi‐Abid, Mohsen Sakly, Riadh Marrouchi   +8 more
wiley   +1 more source