Results 171 to 180 of about 2,453,486 (333)
Topiramate for the treatment of neonatal seizures and beyond
Abstract Acute symptomatic neonatal seizures are one of the most common neurological disorders in newborns admitted to neonatal intensive care units and require prompt treatment. Up to 50% of neonatal seizures are refractory to first‐line medications such as phenobarbital (PB), and another 30% fail second‐line therapy.
Wolfgang Löscher, Janet S. Soul
wiley +1 more source
Carbonic anhydrases constitute a family of metalloenzymes vital for maintaining acid-base balance and regulating pH in physio-pathological processes. These findings suggest carbonic anhydrases as potential therapeutic targets for treating pH-associated ...
Sara Amiranda+13 more
doaj
A Spectrophotometric Method for the Assay of Carbonic Anhydrase Activity. [PDF]
Per Olof Nyman+4 more
openalex +1 more source
Parham Taslimi+7 more
semanticscholar +1 more source
Unconventional structure and function of PHD domains from additional sex combs‐like proteins
A plant homeodomain (PHD) at the C terminus of additional sex combs‐like (ASXL) proteins is recurrently truncated in disease. In the current study, the ASXL PHD was shown not to bind histone modifications. Instead, a complex between the ASXL PHD and methyl CpG‐binding domain proteins 5 and 6 (MBD5/6) was investigated.
Cameron J. Reddington+4 more
wiley +1 more source
Facile synthesis of aminobiphenyl sulfonamides via Chan-Lam coupling and their biological evaluation as potent carbonic anhydrase inhibitors. [PDF]
Sharif M+9 more
europepmc +1 more source
Studies of the Esterase Activity and the Anion Inhibition of Bovine Zinc and Cobalt Carbonic Anhydrases [PDF]
A. Thorslund, S. Lindskog
openalex +1 more source
Systemic Carbonic Anhydrase Inhibitors in Common Ophthalmic Diseases: A Scoping Review from A Clinical Standpoint. [PDF]
Hallaj S+4 more
europepmc +1 more source