Results 51 to 60 of about 2,446,860 (342)

A Proof-of-Concept Fragment Screening of a Hit-Validated 96-Compounds Library against Human Carbonic Anhydrase II

open access: yesBiomolecules, 2020
Fragment screening is a powerful tool to identify and characterize binding pockets in proteins. We herein present the results of a proof-of-concept screening campaign of a versatile 96-entry fragment library from our laboratory against the drug target ...
Steffen Glöckner   +2 more
doaj   +1 more source

Transport metabolons with carbonic anhydrases [PDF]

open access: yesFrontiers in Physiology, 2013
THE CONCEPT OF THE TRANSPORT METABOLON A metabolon has been defined as a “temporary, structural-functional, supramolecular complex of sequential metabolic enzymes and cellular structural elements, in which metabolites are passed from one active site to another without complete equilibration with the bulk cellular fluids” (Srere, 1985, 1987).
Joachim W. Deitmer, Holger M. Becker
openaire   +3 more sources

Covalent Organic Frameworks for Photocatalysis

open access: yesAdvanced Materials, EarlyView.
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra   +6 more
wiley   +1 more source

Effect of Anti-Carbonic Anhydrase Antibodies on Carbonic Anhydrases I and II [PDF]

open access: yesClinical Chemistry, 2003
Carbonic anhydrase (CA; EC 4.2.1.1) is a zinc enzyme that is widely distributed in the living world and is involved in many biochemical processes that depend on the hydration/dehydration of carbon dioxide/bicarbonate [reviewed in Refs. (1)(2)(3)(4)(5)(6)].
BOTRE', Francesco   +4 more
openaire   +3 more sources

Integrating Visible‐Light Photocatalysis and Enzymes for the Stereoselective Synthesis of Alcohols and Amines

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley   +1 more source

Carbonic Anhydrase Inhibitors

open access: yesKidney and Blood Pressure Research, 1987
The purpose of the present review is to describe the use of carbonic anhydrase inhibitors in clinical medicine and renal physiology. We first describe the localization of carbonic anhydrase within the kidney and then discuss evidence for its role in renal acidification and NaCl absorption.
Robert J. Alpern   +2 more
openaire   +3 more sources

Genomic and Cis‐Regulatory Basis of a Plastic C3‐C4 Photosynthesis in Eleocharis Baldwinii

open access: yesAdvanced Science, EarlyView.
The sedge Eleocharis baldwinii remarkably switches between C3‐like and C4‐like photosynthesis in response to environmental conditions. Combining gap‐free genome assembly with single‐cell multi‐omics, this study uncovers how subgenome dominance and cell‐specific cis‐regulation enable C4 photosynthesis.
Lu Chen   +11 more
wiley   +1 more source

Bioinformatics approach based research of profile protein carbonic anhydrase II analysis as a potential candidate cause autism for the variation of learning subjects biotechnology [PDF]

open access: yesJPBI (Jurnal Pendidikan Biologi Indonesia), 2017
This study aims to determine the needs of learning variations on Biotechnology courses using bioinformatics approaches. One example of applied use of bioinformatics in biotechnology course is the analysis of protein profiles carbonic anhydrase II as a ...
Dian Eka A. F. Ningrum   +2 more
doaj   +2 more sources

Immobilization of Carbonic Anhydrase for Biomimetic CO2 Capture

open access: yesChemical Engineering Transactions, 2013
Novel post-combustion treatments include carbon capture and sequestration processes based on biomimetic strategies. These strategies include CO2 absorption into aqueous solution assisted by enzyme catalysis. Carbonic anhydrase catalyses CO2 hydration and
M.E. Russo   +5 more
doaj   +1 more source

Multivalent Carbonic Anhydrases Inhibitors [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Biomolecular recognition using a multivalent strategy has been successfully applied, this last decade on several biological targets, especially carbohydrate-processing enzymes, proteases, and phosphorylases. This strategy is based on the fact that multivalent interactions of several inhibitory binding units grafted on a presentation platform may ...
Fabrizio Carta   +3 more
openaire   +3 more sources

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