Results 11 to 20 of about 5,754,497 (140)
Toll-like Receptor 3 Agonist, Polyinosinic-polycytidylic Acid, Upregulates Carbonic Anhydrase II in Human Keratinocytes [PDF]
Acta Dermato-Venereologica, 2018 Carbonic anhydrases are ubiquitously expressed enzymes that reversibly hydrate carbon dioxide to bicarbonate and protons. While the main function of carbonic anhydrases is to regulate pH and osmotic balance, their involvement in other physiological ...
Bani Kaur Suri +2 more
doaj +3 more sources
Carbonic Anhydrase Type II Deficiency Syndrome
Pediatric Neurology Briefs, 2012 Researchers at King Saud University, Saudi Arabia and other centers describe the neurological, neuro-ophthalmological and neuroradiological features of 23 patients (10 male, 13 female; age at final exam 2-29 years) from 10 unrelated consanguineous ...
J Gordon Millichap
doaj +2 more sources
Türk Oftalmoloji Dergisi, 2017 Objectives: To investigate the relationship between serum carbonic anhydrase I-II (CA-I and II) autoantibody levels and diabetic retinopathy (DRP) in cases with type 1 diabetes. Materials and Methods: A total of 37 type-1 diabetic patients, 17 with DRP (
Adem Türk +6 more
doaj +2 more sources
Carbonic Anhydrase II Deficiency in a Saudi Woman
Clinical Medicine Insights: Case Reports, 2015 Objective Carbonic anhydrase (CA) II deficiency is a rare autosomal recessive disorder caused by mutation in the CA II gene that leads to osteopetrosis, renal tubular acidosis (RTA), and cerebral calcification.
Omar N. Alhuzaim +2 more
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Investigation into the Mechanism of Human Carbonic Anhydrase II [PDF]
, 2012 Human carbonic anhydrase II (HCAII) acts as a carbon dioxide sequestration catalyst, removing carbon dioxide from the blood stream and converting it into bicarbonate and a proton. The active site contains a tetrahedrally coordinated zinc atom coordinated
Saunders, Michael
core +6 more sources
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 The present study aimed to develop potent carbonic anhydrase inhibitors (CAIs). The design of the target compounds was based on modifying the structure of the ureido-based carbonic anhydrase inhibitor SLC-0111.
Mazin A. A. Najm +7 more
doaj +1 more source
Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models [PDF]
, 2015 This research was financed in part by a Grant of the 7th Framework Program of the European Union (METOXIA project; HEALTH‐F2‐2009‐222741) and the NGI Pre- Seed grant (NWO n° 93613002).Triple negative, resistant or metastatic disease are major factors in ...
Kunkler, Ian H. +16 more
core +4 more sources
Inorganic carbon acquisition in Palmaria palmata (Rhodophyta) [PDF]
, 2010 PhDDIC acquisition mechanisms and the use of DIC in photosynthesis were examined in the temperate red macroalga, Palmaria palmata (Linnaeus) O. Kuntze.
Hill, Gregg
core +4 more sources
The effects of cardiac drugs on human erythrocyte carbonic anhydrase I and II isozymes
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Cardiovascular diseases are the leading cause of mortality worldwide. In recent years, the relationship between carbonic anhydrase inhibitors and atherosclerosis has attracted attention.
Onur Argan +3 more
doaj +1 more source
Macedonian Journal of Chemistry and Chemical Engineering, 2021 Mannich bases (2a–d) of aromatic amines were synthesized by using a conventional microwave technique under solvent-free conditions and characterized by IR and NMR (1H and 13C) and elemental analysis.
Bülent Büyükkıdan +5 more
doaj +1 more source