Results 51 to 60 of about 5,754,497 (140)

Catecholamine-induced vasoconstriction is sensitive to carbonic anhydrase I activation

Brazilian Journal of Medical and Biological Research, 2001
We studied the relationship between alpha- and beta-adrenergic agonists and the activity of carbonic anhydrase I and II in erythrocyte, clinical and vessel studies. Kinetic studies were performed.
Puscas I., Coltau M., Gilau L., Pasca R., Domuta G., Baican M., Hecht A.   +6 more
doaj  

Isoxazole–Thiazole Hybrids: Synthesis, Structural Characterisation, Carbonic Anhydrase Inhibition, and Molecular Docking Studies

Molecules
A new series of isoxazole-fused thiazole–oxazole derivatives (11a–n) was rationally designed and synthesised with the aim of developing potent carbonic anhydrase (CA) I and II inhibitors.
Nurcan Berber, Özge Nur Türkeri, Faika Başoğlu, Kubra Çıkrıkcı, Adem Ergün, Nahit Gencer   +5 more
doaj   +1 more source

Carbonic anhydrase inhibition with a series of novel benzenesulfonamide-triazole conjugates

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
We report the synthesis and characterisation of a novel series of triazole benzenesulfonamide derivatives, which incorporate the general pharmacophore associated with carbonic anhydrase (CA, EC 4.2.1.1) inhibitors.
Marwa G. El-Gazzar, Nessma H. Nafie, Alessio Nocentini, Mostafa M. Ghorab, Helmi I. Heiba, Claudiu T. Supuran   +5 more
doaj   +1 more source

Histochemical Localization of Carbonic Anhydrase in the Taste Buds of the Mouse and Goldfish [PDF]

, 1996
P(論文)The activity of carbonic anhydrase in the taste buds of the mouse and goldfish was examined by enzyme histochemistry. An intense reaction of carbonic anhydrase was observed in the middle and basal regions of the taste buds in the mouse circumvallate
37890, 37891, 37892, TAKEDA, Masako, 24883, OBARA, Nobuko, SUZUKI, Yuko, 37888, 37889   +8 more
core  

M1-Type Macrophages Secrete TNF-α to Stimulate Vascular Calcification by Upregulating CA1 and CA2 Expression in VSMCs

Journal of Inflammation Research, 2023
Xianqin Song,1 Yu Song,1 Quanping Ma,2 Kehua Fang,3 Xiaotian Chang1 1Medical Research Center of the Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China; 2Clinical Laboratory, The fourth People’s Hospital of Jinan ...
Song X, Song Y, Ma Q, Fang K, Chang X
doaj  

Synthesis, In Vivo Anticonvulsant Activity Evaluation and In Silico Studies of Some Quinazolin-4(3H)-One Derivatives

Molecules
Two series, “a” and “b”, each consisting of nine chemical compounds, with 2,3-disubstituted quinazolin-4(3H)-one scaffold, were synthesized and evaluated for their anticonvulsant activity.
Raluca Pele, Gabriel Marc, Cristina Mogoșan, Anamaria Apan, Ioana Ionuț, Brîndușa Tiperciuc, Cristina Moldovan, Cătălin Araniciu, Ilioara Oniga, Adrian Pîrnău, Laurian Vlase, Ovidiu Oniga   +11 more
doaj   +1 more source

Azobenzene-based inhibitors of human carbonic anhydrase II

Beilstein Journal of Organic Chemistry, 2015
Aryl sulfonamides are a widely used drug class for the inhibition of carbonic anhydrases. In the context of our program of photochromic pharmacophores we were interested in the exploration of azobenzene-containing sulfonamides to block the catalytic ...
Leander Simon Runtsch, David Michael Barber, Peter Mayer, Michael Groll, Dirk Trauner, Johannes Broichhagen   +5 more
doaj   +1 more source

Surface plasmon resonance applications in drug discovery : with an emphasis on small molecule and low affinity systems [PDF]

, 2005
Surface plasmon resonance (SPR) technology evolved into a key technology for the characterization of biomolecular interactions, and is integrated in many stages of the drug discovery process.
Ricklin, Daniel
core   +1 more source

A radioimmunoassay for quantifying carbonic anhydrase isozymes in crude lysates [PDF]

, 1970
A radioimmunoassay was developed for quantifying each of the two genetically distinct forms of primate carbonic anhydrase, carbonic anhydrases I and II, in unpurified lysates.
Headings, Verle E., Verle E. Headings, Richard E. Tashian, Tashian, Richard E.   +3 more
core   +1 more source

A quantitative assessment of the carbonic anhydrase activity in photosystem II [PDF]

, 2015
Using a carbonic anhydrase assay based on membrane inlet mass spectrometry (MIMS), we have extended our earlier investigations of Photosystem II (PSII)-associated carbonic anhydrase activity in spinach PSII preparations (W. Hillier, I. McConnell, M.
Badger, Murray, McConnell, Iain, Wydrzynski, Thomas, Hillier, Warwick   +3 more
core   +2 more sources