Results 101 to 110 of about 47,659 (268)

Vitreoretinal complications and surgical outcomes in patients with X‐linked retinoschisis

Acta Ophthalmologica, EarlyView.
Abstract Purpose X‐linked retinoschisis (XLRS) is an inherited vitreoretinal disorder characterized by macular retinoschisis. In a subgroup of patients, peripheral retinoschisis can occur, potentially leading to complications such as vitreous haemorrhage (VH) and retinal detachment (RD).
Jonathan Hensman, Leo C. Hahn, Mary J. van Schooneveld, Roselie M. H. Diederen, Filip van den Broeck, Jacoline B. Ten Brink, Alberta A. Thiadens, Maria M. van Genderen, L. Ingeborgh van den Born, Bart P. Leroy, Carel B. Hoyng, Camiel J. F. Boon   +11 more
wiley   +1 more source

Retinal oxygen saturation and retinal vessel diameter in glaucoma patients before and after trabeculectomy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To compare retinal vessel oxygen saturations and diameters before, 1 and 3 months after trabeculectomy. Methods Retinal oxygen saturations and vessel diameters were obtained using retinal oximetry. The effect of the postoperative intraocular pressure (IOP) decrease on the arteriovenous difference (AV‐difference) was evaluated ...
S. Kemp, A. Ahmadzadeh, B. Schmidt, O. N. Klefter, L. Kessel, D. Bach‐Holm   +5 more
wiley   +1 more source

The retinal relaxing factor : update on an enigmatic regulator of the retinal circulation [PDF]

, 2017
The retinal circulation is regulated by different local factors and might include the retinal relaxing factor (RRF). This factor is found to be continuously released by the retina and relaxes smooth muscle cells.
Boydens, Charlotte, Pauwels, Bart, Van de Voorde, Johan, Vanden Daele, Laura   +3 more
core   +2 more sources

Oligoprogressive renal cell carcinoma: What is the role of surgery?

BJU International, EarlyView.
Objective To provide an overview of the biological mechanism and pattern of oligoprogression in renal cell carcinoma (RCC) and the most updated role of surgery in this setting, highlighting scientific gaps and informing future implications. Methods A non‐systematic search of PubMed/MEDLINE was performed in August 2025 including guidelines, reviews, and
Chiara Re, William H.J. Ince, Leo Bickley, James P. Blackmur, Mouhamad H. Ismail, Justicia Kyeremeh, Teele Kuusk, Eva Mendes Serrao, James O. Jones, Grant D. Stewart   +9 more
wiley   +1 more source

Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. [PDF]

, 2015
Carbonic anhydrase IX (CAIX) is strongly induced by hypoxia and its overexpression is associated with poor therapeutic outcome in cancer. Here, we report that hypoxia promotes tumour heterogeneity through the epigenetic regulation of CAIX.
Akslen, Bodmer, Bonafe, Chen, Dedhar, Dontu, Dontu, Fu, Fuller, Hall, Harris, Harris, Harris, Harris, Harris, Kaanders, Katoh, Kretsovali, Kubbies, Lee, Miller, Mori, Pacheco, Park, Pascual-Montano, Pascual-Montano, Pastorekova, Petersen, Rich, Rich, Salzberg, Stanbridge, Vaughan-Jones   +32 more
core   +3 more sources

A novel thiadiazole-based dual inhibitor of carbonic anhydrase-IX and epidermal growth factor receptor targeting cancer: A combined and approach

Journal of Chemical Research
The co-expression of epidermal growth factor receptor and carbonic anhydrase-IX in aggressive tumors such as triple-negative breast cancer contributes to therapeutic resistance through proliferative signaling and hypoxia-mediated adaptation.
Eslam B Elkaeed, Hazem Elkady, Walid E Elgammal, Hazem A Mahdy, Dalal Z Husein, Ibrahim M Ibrahim, Hanan A Al-ghulikah, Ibrahim H Eissa, Ahmed M Metwaly   +8 more
doaj   +1 more source

Neuroprotective Potential of Ethoxzolamide Targeting Oxidative Stress and Inflammation in Experimental Models of Intracerebral Hemorrhage

Frontiers in Bioscience-Landmark
Background: As antioxidant and anti-inflammatory agents, carbonic anhydrase inhibitors can exert potentially useful therapeutic effects following central nervous system trauma, including intracerebral hemorrhage (ICH).
Yongxia Li, Gang Shen, Jiarui Du, Wei Dai, Zuopeng Su   +4 more
doaj   +1 more source

Irreversible thermal denaturation of human carbonic anhydrase [PDF]

Carbonic Anhydrase (CA; carbonate hydro-lyase, EC 4.2.1.1)), a zinc containing enzyme, catalyzes reversible hydration of carbon dioxide. This metalloenzyme is found in animals, photosynthesizing organisms, and in some nonphotosynthetic bacteria. Thermal
امانی, مجتبی, خدارحمی, رضا, قبادی, سیروس, محرابی, معصومه, موسوی موحدی, علی اکبر   +4 more
core  

Proteomic Analysis of High-CO2-Inducible Extracellular Proteins in the Unicellular Green Alga, Chlamydomonas reinhardtii [PDF]

, 2011
The unicellular green alga Chlamydomonas reinhardtii can acclimate to a wide range of CO2 concentrations through the regulation of a CO2-concentrating mechanism (CCM).
Baba Masato, Shiraiwa Yoshihiro, Suzuki Iwane, 白岩 善博, 鈴木 石根, 馬場 将人   +5 more
core   +1 more source

Carbonic Anhydrase Inhibitor Modulation of Intraocular Pressure Is Independent of Soluble Adenylyl Cyclase. [PDF]

J Ocul Pharmacol Ther, 2023
Wiggins SV, Schreiner R, Ferreira J, Marmorstein AD, Levin LR, Buck J.   +5 more
europepmc   +1 more source