Results 151 to 160 of about 47,659 (268)

Mitochondrial β‐carbonic anhydrase is a conserved metabolic rheostat for branched‐chain amino acid catabolism and metabolic flexibility

open access: yesNew Phytologist, Volume 250, Issue 4, Page 2415-2427, May 2026.
Summary Carbonic anhydrases (CAs) are ubiquitous metalloenzymes that catalyze the reversible hydration of CO2, enabling fundamental processes in organisms across all domains of life. Among all CAs, the role of mitochondrial βCA remains poorly understood. Here, we identify a mitochondrial βCA, βCA6, as a key regulator of branched‐chain amino acid (BCAA)
Naveen Sharma   +2 more
wiley   +1 more source

An atlas of plant selenium metabolism

open access: yesNew Phytologist, Volume 250, Issue 4, Page 2041-2060, May 2026.
Summary Selenium (Se) is not only a rare and toxic element but also an essential micronutrient for humans and animals that is often in short supply. Terrestrial plants do not require Se, but it can have growth‐promoting or negative effects, depending on the exposure level.
Jeroen van der Woude   +3 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, Volume 20, Issue 4, Page 877-893, April 2026.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Role of Histidine‐Containing Peptoids in Accelerating the Kinetics of Calcite Growth

open access: yesAdvanced Functional Materials, Volume 36, Issue 34, 27 April 2026.
Amphiphilic histidine‐containing peptoids mimic carbonic anhydrase (CA) to accelerate calcite step growth. In the presence of Zn2+, they promote the deprotonation of HCO3−, the desolvation of Ca2+, and the reorganization of interfacial hydration layers, thereby reducing the activation barrier for calcite growth.
Mingyi Zhang   +5 more
wiley   +1 more source

Maize Anther Development Involves Translated Open Reading Frames From 3′ Untranslated Regions

open access: yesAdvanced Science, Volume 13, Issue 23, 23 April 2026.
This study examined the translation activity across ten stages of maize anther development, integrating transcriptome and small‐peptide data. It linked mutations in translated 3' ORFs to anther sterility, exemplified by Zm00001eb417050_3' ORF (known as APV1). In addition, the data indicated that maize anthers could assimilate CO2 through the stomata in
Chunyu Wang   +8 more
wiley   +1 more source

The Evolution of Giant Clam Science: From Foundational Studies to Emerging Frontiers

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
This review synthesizes nearly two centuries of giant clam research, identifying dominant themes, knowledge gaps, and emerging opportunities. Ecology, physiology, aquaculture, genomics, and biomineralization dominate the field, whereas anatomy and biotechnology remain underexplored. Future progress requires stronger integration of genomics, physiology,
Anthony Fam   +4 more
wiley   +1 more source

CBr4‐Mediated Metal‐Free Sulfonamide Synthesis: A Comparative Study Under Batch, Continuous‐Flow and Ultrasonic Conditions

open access: yesAsian Journal of Organic Chemistry, Volume 15, Issue 4, April 2026.
A practical and efficient CBr4‐mediated metal‐free route for sulfonamide synthesis is presented under batch, ultrasonic, and continuous‐flow conditions. The protocol demonstrates excellent substrate scope, reduced reaction times, and mild operating conditions, highlighting a scalable alternative to traditional iodine‐mediated methods in modern ...
Alageswaran Jayaram   +6 more
wiley   +1 more source

6-Methylsulfinylhexyl isothiocyanate activates carbonic anhydrase-dependent HCO<sub>3</sub> <sup>-</sup>/H<sup>+</sup>/Na<sup>+</sup>/Ca<sup>2+</sup> transport via SLC4As-NHE-NCX-PMCA axis in odontoblasts. [PDF]

open access: yesJ Physiol
Abstract figure legend 6‐Methylsulfinylhexyl isothiocyanate (6‐MSITC, hexaraphane), a wasabi sulfinyl compound, activates intracellular carbonic anhydrase (CA)‐mediated sequential HCO3−, Na+, H+ and Ca2+ transport through an activation axis involving HCO3−‐transporting solute carrier family 4 (SLC4As), the Na+–H+ exchanger (NHE), the Na+–Ca2+ exchanger
Furusawa Y   +9 more
europepmc   +2 more sources

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