Results 11 to 20 of about 109,847 (333)
Carbonic Anhydrase Inhibitors from Marine Natural Products. [PDF]
Mar Drugs, 2022 Carbonic anhydrases (CAs, EC 4.2.1.1) are widespread metalloenzymes in organisms in all life kingdoms, being involved in pH regulation, metabolic processes and many other physiological and pathological conditions.
Supuran CT.
europepmc +2 more sources
An overview of carbohydrate-based carbonic anhydrase inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Carbonic anhydrases (CAs) are metalloenzymes responsible for the reversible hydration of carbon dioxide to bicarbonate, a fundamental reaction involved in various physiological and pathological processes.
Doretta Cuffaro +2 more
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The carbonic anhydrase inhibitor in serum [PDF]
The Journal of Physiology, 1938 V. H. Booth
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Azobenzene-based inhibitors of human carbonic anhydrase II [PDF]
Beilstein Journal of Organic Chemistry, 2015 Aryl sulfonamides are a widely used drug class for the inhibition of carbonic anhydrases. In the context of our program of photochromic pharmacophores we were interested in the exploration of azobenzene-containing sulfonamides to block the catalytic ...
Leander Simon Runtsch +5 more
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Quantitative Characterization of the Chemical Space Governed by Human Carbonic Anhydrases and selenium-containing derivatives of solfonamides [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2022 Due to the fact that different isoforms of carbonic anhydrase play distinct physiological roles, their diseases/disorders involvement are different as well.
Behnam Rasti
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Carbonic anhydrase inhibitors for the treatment of glaucoma
Медицинская этика, 2023 Glaucoma is the leading cause of irreversible blindness. Its leading symptom and the most important initial link of the disease pathogenesis is represented by an increase of intraocular pressure (IOP).
V. Strakhov +6 more
semanticscholar +1 more source
A clinical case of choroidal effusion associated with the use of carbonic anhydrase inhibitors
Офтальмохирургия, 2021 Relevance. Choroidal effusion is a complication accompanying both surgical interventions and ophthalmopathies of predominantly inflammatory etiology. The release of proteins from choriocapillaries lumen and decrease of intraocular pressure relative to ...
N. I. Kurysheva +3 more
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Serious Adverse Events of Oral and Topical Carbonic Anhydrase Inhibitors.
JAMA ophthalmology, 2022 Importance Some ophthalmologists may be reluctant to prescribe oral carbonic anhydrase inhibitors, given the potential for life-threatening systemic adverse reactions.
M. Popovic +3 more
semanticscholar +1 more source
Microbiology Spectrum, 2023 The ADC (AmpC) β-lactamase is universally present in the Acinetobacter baumannii chromosome, suggesting it may have a yet-to-be-identified cellular function. Using peptidoglycan composition analysis, we show that overexpressing the ADC-7 β-lactamase in A.
Jennifer M. Colquhoun +6 more
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Measuring kinetic parameters using quantum plasmonic sensing [PDF]
Phys. Rev. A 105, 032619 (2022), 2021 The measurement of parameters that describe kinetic processes is important in the study of molecular interactions. It enables a deeper understanding of the physical mechanisms underlying how different biological entities interact with each other, such as viruses with cells, vaccines with antibodies, or new drugs with specific diseases. In this work, we
arxiv +1 more source