The effects of cardiac drugs on human erythrocyte carbonic anhydrase I and II isozymes
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Cardiovascular diseases are the leading cause of mortality worldwide. In recent years, the relationship between carbonic anhydrase inhibitors and atherosclerosis has attracted attention.
Onur Argan +3 more
doaj +1 more source
Carbonic Anhydrase Inhibitors in the Treatment of Glaucoma. Review. Part I
Oftalʹmologiâ, 2020 Glaucoma is the main cause of irreversible blindness in the world. Carbonic anhydrase inhibitors (CAIS) used both systemically and topically, reduce intraocular pressure effectively.
N. I. Kurysheva
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Role of carbon dioxide and ion transport in the formation of sub-embryonic fluid by the blastoderm of the Japanese quail [PDF]
, 2002 1. The explanted blastoderm of the Japanese quail was used to explore the role of ions and carbon dioxide in determining the rate of sub-embryonic fluid (SEF) production between 54 and 72 h of incubation. 2.
Latter, G.V., Baggott, Glenn K.
core +1 more source
Bioinformatics Tools for the Analysis of Active Compounds Identified in Ranunculaceae Species
Pharmaceuticals, 2023 The chemical compounds from extracts of three Ranunculaceae species, Aconitum toxicum Rchb., Anemone nemorosa L. and Helleborus odorus Waldst. & Kit.
Cătălina Mareş +3 more
doaj +1 more source
Dithiocarbamates effectively inhibit the α-carbonic anhydrase from Neisseria gonorrhoeae
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Recently, inorganic anions and sulphonamides, two of the main classes of zinc-binding carbonic anhydrase inhibitors (CAIs), were investigated for inhibition of the α-class carbonic anhydrase (CA, EC 4.2.1.1) from Neisseria gonorrhoeae, NgCA.
Simone Giovannuzzi +7 more
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Selective Carbonic Anhydrase IX and XII Inhibitors Based Around a Functionalized Coumarin Scaffold [PDF]
, 2023 Inhibition of specific carbonic anhydrase (CA) enzymes is a validated strategy for the development of agents to target cancer. The CA isoforms IX and XII are overexpressed in various human solid tumors wherein they play a critical role in regulating ...
Claudiu, Supuran +13 more
core +2 more sources
Management of glaucoma in pregnancy: risks or choices, a dilemma? [PDF]
International Journal of Ophthalmology, 2016 The treatment of glaucoma in and around pregnancy offers the unique challenge of balancing the risk of vision loss to the mother as against the potential harm to the fetus or newborn. Most anti-glaucoma drugs (i.e. beta-blockers, prostaglandin analogues,
Harinder Singh Sethi +2 more
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Carbonic anhydrase inhibitors: an editorial [PDF]
Expert Opinion on Therapeutic Patents, 2013 This issue of Expert Opinion on Therapeutic Patents is dedicated to carbonic anhydrase (CA, EC 4.2.1.1) inhibitors (CAIs), a highly dynamic research topic in the last years. Several review articles and patent analyses on diuretics and antiglaucoma, antiepileptic, anti-obesity and anticancer agents belonging to the pharmacological class of the CAIs are ...
openaire +2 more sources
Effect of egg turning and incubation time on carbonic anhydrase gene expression in the blastoderm of the Japanese quail (Coturnix c. japonica) [PDF]
, 2008 (1) The gene expression of carbonic anhydrase, a key enzyme for the production sub-embryonic fluid (SEF), was assessed in turned and unturned eggs of the Japanese quail.
Baggott, G. K. +5 more
core +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 In search of selective carbonic anhydrase (CA) IX inhibitors endowed with apoptotic inducing properties, we designed and synthesised two subsets of 4- and 3-(5-aryl-(4-phenylsulphonyl)-1H-1,2,3-triazol-1-yl)benzenesulphonamides.
Kiran Siwach +7 more
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