Results 191 to 200 of about 648,149 (287)

Crocus sativus (Saffron) Aqueous Extract Mediated Green Synthesis of Iron Oxide Nanoparticles and Their In Vitro and In Vivo Biological Investigations

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
The Crocus sativus (saffron) aqueous extract mediated green synthesis of iron oxide nanoparticles and their in vitro and in vivo biological investigations. ABSTRACT The present study reports the green synthesis of iron oxide nanoparticles (IONPs) using the aqueous extract of Crocus sativus (saffron) as a natural reducing and stabilizing agent, followed
Abdur Rauf, Khurram Shehzad, Hira Naeem, Shahkar Usama, Zubair Ahmad, Bilal Khan, Naveed Muhammad, Muhammad Shafique, Yahya S. Al‐Awthan, Omar S. Bahattab, Mohammed Mansour Quradha   +10 more
wiley   +1 more source

Hyaluronic Acid-Palmitate Nanoparticle Delivery of Carbonic Anhydrase Inhibitors Impairs Growth and Early Metabolism in <i>Escherichia coli</i> Through β- and γ-Carbonic Anhydrase-Associated Processes. [PDF]

Int J Mol Sci
De Luca V, Verdoliva V, Supuran CT, De Luca S, Capasso C.   +4 more
europepmc   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, Volume 3, Issue 3, September 2026.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

Privileged Scaffold Hybridization in the Design of Carbonic Anhydrase Inhibitors. [PDF]

Molecules
Secci D, Sanna E, Distinto S, Onali A, Lupia A, Demuru L, Atzeni G, Meleddu R, Cottiglia F, Angeli A, Supuran CT, Maccioni E.   +11 more
europepmc   +1 more source

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi‐Target Inhibitors of Cholinesterases and Carbonic Anhydrases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Seda Ünlü, Zeynep Köksal, Kevser Kübra Kırboğa, Fikriye Tuncel Elmalı   +3 more
wiley   +1 more source

Cascade-activatable NIR-II fluorescent carbonic anhydrase inhibitors for imaging-guided cuproptosis/chemodynamic combination therapy of colorectal cancer. [PDF]

Chem Sci
Xu P, Huang Y, Liu G, Gu X, Sun X, Bi Y, Zhou W, Xie C, Fan Q.   +8 more
europepmc   +1 more source

The Evolution of Medications for Obesity Management

JGH Open, Volume 10, Issue 9, September 2026.
ABSTRACT This narrative review provides an overview of progress in the development of obesity medications, including a synthesis of data describing the efficacy and safety of currently available agents and emerging therapeutic options. Historically, many obesity medications have been withdrawn from the market due to safety concerns.
Jaskirath Gill, Priya Sumithran
wiley   +1 more source

Dual targeting carbonic anhydrase inhibitors as promising therapeutic approach: a structural overview. [PDF]

Front Mol Biosci
D'Ambrosio K, Di Fiore A, Langella E.
europepmc   +1 more source

My Love Story With HIFs in the Disc: A Journey to the Humboldt Research Award

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT The intervertebral disc is a prime example of tissue adaptation to metabolic and mechanical extremes. As the largest avascular organ in the human body, the disc and the central nucleus pulposus (NP) endure constant compressive loading while sustaining a hypoxic, relatively acidic, and hyperosmotic microenvironment that would be inhospitable to
Makarand V. Risbud
wiley   +1 more source

Advances in Organic Aggregates for Biomedical Phototheranostics

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Organic aggregates offer aggregation‐regulated photophysical properties for biomedical phototheranostics, enabling enhanced fluorescence, stabilized room‐temperature phosphorescence, and efficient photoacoustic/photothermal responses. This review highlights molecular design strategies, excited‐state energy modulation, biomedical applications, and ...
Bowen Fu, Yayun Peng, Ting Cai
wiley   +1 more source