Results 211 to 220 of about 648,149 (287)

Renally Generated Ammonia as a Cause of Hyperammonaemic Non‐Hepatic Encephalopathy

Nephrology, Volume 31, Issue 9, September 2026.
ABSTRACT Encephalopathy with high ammonia levels is most commonly associated with cirrhosis or urea cycle disorders, but it can also result from renal ammoniagenesis when renal excretion of ammonium is impaired. In the literature, this has been shown to occur in the presence of (1) urinary diversion to a segment of intestine; (2) urea‐splitting ...
Victoria E. Nkunu, Kevin Y. L. Mak, Kuldeep Dodia, Fraulein D. Morales, Alicia K. J. Chan, R. Todd Alexander, Peter M. Hwang   +6 more
wiley   +1 more source

Hydrogen Sulfide-Releasing Carbonic Anhydrase Inhibitors Effectively Suppress Cancer Cell Growth. [PDF]

Int J Mol Sci
Bonardi A, Nocentini A, de Luca V, Capasso C, Elkaeed EB, Eldehna WM, Supuran CT.   +6 more
europepmc   +1 more source

Clinical Characterization of Glaucoma in 63 Pet Rabbits (Oryctolagus cuniculus) in Japan

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective To characterize the signalment and clinical presentation of glaucoma in pet rabbits. Animal Studied Client‐owned pet rabbits (n = 222) referred to an exotic specialty animal hospital for ophthalmic examination between 2007 and 2023.
Kumiko Kato, Makoto Nakata, Yasutsugu Miwa, Keiko Miyadera   +3 more
wiley   +1 more source

X-ray crystallographic and kinetic studies of biguanide containing aryl sulfonamides as carbonic anhydrase inhibitors. [PDF]

RSC Med Chem
Baroni C, Bozdag M, Renzi G, De Luca V, Capasso C, Bazzicalupi C, Selleri S, Ferraroni M, Carta F, Supuran CT.   +9 more
europepmc   +1 more source

Pre‐ and Post‐Phacoemulsification Morphologic Iridocorneal Angle Analysis by Anterior Segment Gonioscopic Imaging as a Predictor of Postoperative Glaucoma in Dogs

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective To serially assess iridocorneal angle (ICA) gonioscopic morphology following phacoemulsification in dogs and to determine whether postoperative changes are associated with the development aphakic/pseudophakic glaucoma. Animals Studied Client‐owned dogs presented for cataract removal by phacoemulsification.
Steven R. Hanes, Renata V. Ramos, Ian P. Herring, Roxanne M. Rodriguez‐Galarza   +3 more
wiley   +1 more source

Design, synthesis, molecular modelling investigation and biological studies of novel human carbonic anhydrase inhibitors based on coumalic acid. [PDF]

RSC Med Chem
Pontecorvi V, Angeli A, Cutarella L, Mori M, Secci D, Coluccia M, Carradori S, Troiani A, Pepi F, Salvitti C, Di Noi A, Spano M, Arrighi F, De Falco E, Bordin A, Berrino E, Granese A, Chimenti P, Guglielmi P, Supuran CT.   +19 more
europepmc   +1 more source

Outcomes of 39 Canine Eyes Treated With Combined Endoscopic Cyclophotocoagulation and Ahmed Valve Gonioimplantation for Glaucoma

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Purpose To evaluate the long‐term (> 1 year) outcomes of vision and intraocular pressure (IOP) control in dogs with glaucoma undergoing combined endoscopic cyclophotocoagulation (ECP) and Ahmed valve gonioimplantation (AVG). Methods Medical records between 2020 and 2025 were reviewed. Outcomes evaluated included IOP control (< 25 mmHg), vision
Sanskruti S. Potnis, Ana Ripolles‐Garcia, Kathryn L. Good, Jennifer E. Sheahan, Ruby B. Goldenberg, Kunbee Michael Chang, Sara M. Thomasy   +6 more
wiley   +1 more source

Structure based exploration of mitochondrial alpha carbonic anhydrase inhibitors as potential leads for anti-obesity drug development. [PDF]

Daru
Padhy I, Sharma T, Banerjee B, Mohapatra S, Sahoo CR, Padhy RN.   +5 more
europepmc   +1 more source

Restoring Meropenem Activity Against VIM‐1‐Producing Klebsiella pneumoniae Through Zinc‐Binding Ligands

ChemBioChem, Volume 27, Issue 16, 27 August 2026.
Approved zinc‐binding drugs and newly synthesized HisPyr ligands were evaluated as adjuvants to meropenem against metallo‐β‐lactamase‐producing Klebsiella pneumoniae. Chlorpropamide and D‐penicillamine restored meropenem activity against the VIM‐1‐producing strain, while computational analyses supported interactions with the enzyme's binuclear zinc ...
Chiara Ragusa, Ruqaiya Khalil, Valentina Giglio, Kaveh Eskandari, Fraser J. Scott, Attilio V. Vargiu, Graziella Vecchio   +6 more
wiley   +1 more source