Results 91 to 100 of about 27,386 (335)

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

In Silico Assessment of Enaminone–Sulfanilamides as Potential Carbonic Anhydrase II Inhibitors: Molecular Docking and ADMET Prediction

Chemistry Proceedings
Carbonic anhydrases (CAs) are a group of zinc-containing enzymes involved in many physiological processes through their role in the maintenance of the equilibrium between bicarbonate and CO2 levels.
Yousra Ouafa Bouone, Abdeslem Bouzina, Rachida Mansouri, Nour-Eddine Aouf   +3 more
doaj   +1 more source

The tumour-associated carbonic anhydrases CA II, CA IX and CA XII in a group of medulloblastomas and supratentorial primitive neuroectodermal tumours: an association of CA IX with poor prognosis

BMC Cancer, 2010
Background Medulloblastomas (MBs) and supratentorial primitive neuroectodermal tumours (PNETs) are the most common highly aggressive paediatric brain tumours.
Waheed Abdul, Pastorek Jaromir, Pastorekova Silvia, Laine Jukka, Parkkila Anna-Kaisa, Niemelä Anssi, Korja Miikka, Haapasalo Joonas, Nordfors Kristiina, Sly William S, Parkkila Seppo, Haapasalo Hannu   +11 more
doaj   +1 more source

A Left-handed β Helix Revealed by the Crystal Structure of a Carbonic Anhydrase from the Archaeon Methanosarcina thermophila [PDF]

, 1996
A carbonic anhydrase from the thermophilic archaeon Methanosarcina thermophila that exhibits no significant sequence similarity to known carbonic anhydrases has recently been characterized.
Alber, Birgit E., Ferry, James G., Kisker, Caroline, Rees, Douglas C., Schindelin, Hermann   +4 more
core  

Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes [PDF]

, 2014
This study was funded by the Sars Centre core budget to M. Adamska. Sequencing was performed at the Norwegian High Throughput Sequencing Centre funded by the Norwegian Research Council. O.M.R. and D.E.K.F.
A Saudemont, B Fahey, B Li, C Larroux, C Larroux, D Chourrout, D Darriba, DEK Ferrier, GN Luke, H-C Seo, J Garcia-Fernàndez, JF Ryan, JHL Hui, JHL Hui, KJ Peterson, M Boetzer, M Srivastava, MG Grabherr, N Takatori, O Mendivil Ramos, R Luo, S Amano, S Anders, S Fortunato, S Leininger, SA Fortunato, TM Keane, Y-F Zhong   +27 more
core   +2 more sources

Nanozymes for Energy and Environmental Sustainability

Advanced Science, EarlyView.
At present, the widely used nanozymes are oxidoreductase and hydrolase, which have proved to have great application prospects in energy and environment. ABSTRACT Nanozymes have shown remarkable promise in addressing pressing challenges in energy and environmental sustainability.
Xiaoqi Li, Jinxing Chen, Shaojun Dong
wiley   +1 more source

Metabolic Effect of Estrogen Receptor Agonists on Breast Cancer Cells in the Presence or Absence of Carbonic Anhydrase Inhibitors

Metabolites, 2016
Metabolic shift is one of the major hallmarks of cancer development. Estrogen receptor (ER) activity has a profound effect on breast cancer cell growth through a number of metabolic changes driven by its effect on transcription of several enzymes ...
Anissa Belkaid, Miroslava Čuperlović-Culf, Mohamed Touaibia, Rodney J. Ouellette, Marc E. Surette   +4 more
doaj   +1 more source

Beta-carbonic anhydrases play a role in fruiting body development and ascospore germination in the filamentous fungus Sordaria macrospora.

PLoS ONE, 2009
Carbon dioxide (CO(2)) is among the most important gases for all organisms. Its reversible interconversion to bicarbonate (HCO(3) (-)) reaches equilibrium spontaneously, but slowly, and can be accelerated by a ubiquitous group of enzymes called carbonic ...
Skander Elleuche, Stefanie Pöggeler
doaj   +1 more source

Major contribution of the type II beta carbonic anhydrase CanB (Cj0237) to the capnophilic growth phenotype of Campylobacter jejuni [PDF]

, 2016
Campylobacter jejuni, the leading cause of human bacterial gastroenteritis, requires low environmental oxygen and high carbon dioxide for optimum growth, but the molecular basis for the carbon dioxide requirement is unclear. One factor may be inefficient
Alazzam, Alber, Allos, Bolton, Bury-Moné, Capasso, Carta, Covarrubias, Cronk, Cronk, De Simone, Dugar, Eichler, Epps, Fernandez, Ferry, Fraser, Gai, Gaskin, Gibson, Gielda, Guccione, Guilloton, Gundogdu, Hani, Hermans, Hofreuter, Hofreuter, Hofreuter, Innocenti, Jitrapakdee, Kakuda, Kaur, Kelley, Kelly, Kelly, Kendall, Kusian, Lotlikar, Marcus, Menefee, Merlin, Muraoka, Ozensoy Guler, Parkhill, Pinard, Sheppard, Smith, Sokol, St Maurice, Stahl, Stahl, Stähler, Supuran, Supuran, Supuran, Velayudhan, Velayudhan, Vilas, Vliet, Vorwerk, Wilks   +61 more
core   +1 more source

Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
A diverse set of mono- and bis-sulfonamide was obtained via a direct, chemoselective sulfochlorination of readily available yet hitherto unexplored N-arylpyrazole template.
Mikhail Krasavin, Mikhail Korsakov, Oksana Ronzhina, Tiziano Tuccinardi, Stanislav Kalinin, Muhammet Tanç, Claudiu T. Supuran   +6 more
doaj   +1 more source