Results 161 to 170 of about 7,953 (283)

Roles of three carbonic anhydrases in <i>in vitro</i> growth, pH homeostasis, metabolism, and intracellular survival of <i>Neisseria gonorrhoeae</i>. [PDF]

FEMS Microbes
Alokabandara SV, Liang HW, Bandara AB.
europepmc   +1 more source

Structure and function of carbonic anhydrases [PDF]

FEBS Letters, 1977
Kannan, K.K., Petef, M., Fridborg, K., Cid-Dresdner, H., Lo¨vgren, S.   +4 more
openaire   +2 more sources

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

Experimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr, Philip N. Ainslie, Trevor Day   +2 more
wiley   +1 more source

Machine learning-guided discovery of thermophilic carbonic anhydrases from environmental metagenomes. [PDF]

Sci Rep
Pairoh S, Mhuantong W, Boonyapakron K, Yuvaniyama J, Kanokratana P, Bunterngsook B, Lekakarn H, Arunrattanamook N, Laothanachareon T, Champreda V.   +9 more
europepmc   +1 more source

Carbonic Anhydrases: A Superfamily of Ubiquitous Enzymes. [PDF]

Int J Mol Sci, 2023
Capasso C.
europepmc   +1 more source

Phenylalanine Versus Tyrosine (Pos. 367/332 in MCT1/MCT4) in the Substrate Binding Site Defines Affinity and Preferred Directionality of Human Monocarboxylate Transporters 1–4

Acta Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Aim Human monocarboxylate transporters 1–4, MCT, are key for the lactate/H+ exchange between glycolytic and oxidative cancer cells, white and red muscle fibers, or in the astrocyte‐neuron shuttle. The common MCT transport mechanism involves three conserved residues, that is, a substrate‐attracting Lys and a conformation‐locking Asp/Arg salt ...
Maike Menzel, Ioana‐Daniela Dumitru, Josh Peters, Jan‐Bernd Hövener, Andrey N. Pravdivtsev, Ana‐Nicoleta Bondar, Eric Beitz   +6 more
wiley   +1 more source

Discovery of a Novel Coumarin/Thiazole Chalcone Hybrid as a Potent Dual Inhibitor of Tubulin and Carbonic Anhydrases IX & XII with Promising Anti-Proliferative Activity. [PDF]

Molecules
Saleem BAA, Qurtam AA, Ahmed M, Al-Aouadi RFA, Alrikabi AAA, Hetta HF, Bräse S, Alotaibi G, Alkhammash A, Farhan SM.   +9 more
europepmc   +1 more source

Targeting Tumor-Associated Carbonic Anhydrases in Photothermal Therapy. [PDF]

ChemMedChem
Clément S, Richeter S, Winum JY.
europepmc   +1 more source

Design and synthesis of isoxazole-functionalized benzene sulphonamides as novel inhibitors of <i>Mycobacterium tuberculosis</i> β-carbonic anhydrases. [PDF]

RSC Med Chem
Bandela R, Singampalli A, Maddipatla S, Kumar P, Bellapukonda SM, Ramavath R, Mahajan LS, Nanduri S, Vemula D, Dalal A, Kalia NP, Bhandari V, Gratteri P, Paoletti N, Bonardi A, Supuran CT, Yaddanapudi VM.   +16 more
europepmc   +1 more source

New isoxazolidinyl-based N-alkylethanolamines as new activators of human brain carbonic anhydrases. [PDF]

J Enzyme Inhib Med Chem, 2023
Cuffaro D, Di Leo R, Ciccone L, Nocentini A, Supuran CT, Nuti E, Rossello A.   +6 more
europepmc   +1 more source