Results 181 to 190 of about 7,953 (283)

Endogenously generated Dutch‐type Aβ non‐fibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract BACKGROUND APPE693Q (“Dutch”) transgenic mice develop aging‐related learning deficits and accumulate endogenously generated non‐fibrillar aggregates (NFAs) of amyloid beta (Aβ) and amyloid precursor protein α‐carboxy terminal fragments. NFA‐Aβ correlates with synaptic loss and memory deficits more closely than does fibrillar Aβ.
Emilie L. Castranio, Merina Varghese, Elentina K. Argyrousi, Kuldeep Tripathi, Yong Huang, Akiko Asada, Linda Söderberg, Erin Bresnahan, David Lerner, Francesca Garretti, Hong Zhang, Jonathan van de Loo, Cheryl D. Stimpson, Ronan Talty, Charles Glabe, Efrat Levy, Minghui Wang, Marjan Ilkov, Toshiharu Suzuki, Kanae Ando, Bin Zhang, Lars Lannfelt, Brigitte Guérin, William D. Lubell, Shai Rahimipour, Dara L. Dickstein, Sam Gandy, Ottavio Arancio, Michelle E. Ehrlich   +28 more
wiley   +1 more source

Structural, nonlinear optical, and molecular docking studies of schiff base compounds as multi-target inhibitors of AChE, BChE, and carbonic anhydrases. [PDF]

Sci Rep
Kourat O, Benhalima N, Al-Dies AM, Guendouzi A, Benyahlou ZD, Megrouss Y, Drissi M, Alem GA, Sindi ER, Zaki MEA.   +9 more
europepmc   +1 more source

A Selective Phenyl Azo Acetate Substrate for Enhanced Carbonic Anhydrase Functional Analysis

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Carbon dioxide (CO2) sequestration is a key strategy for mitigating climate change, and biocatalytic approaches offer sustainable, cost‐effective alternatives to chemical and physical methods. Carbonic anhydrases (CAs) efficiently catalyse the reversible hydration of CO2 to bicarbonate, yet their large‐scale application is constrained by ...
Justinas Babinskas, Inga Matijošytė
wiley   +1 more source

RETRACTED: Sarnella et al. A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity. <i>Int. J. Mol. Sci.</i> 2020, <i>21</i>, 8405. [PDF]

Int J Mol Sci
Sarnella A, D'Avino G, Hill BS, Alterio V, Winum JY, Supuran CT, De Simone G, Zannetti A.   +7 more
europepmc   +1 more source

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

Beyond CO2: Incorporating Bicarbonate, Dynamic Carbon Speciation, and Stoichiometric Plasticity Into Algal Growth Models

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1491-1502, June 2026.
ABSTRACT The design of biological carbon capture systems to uptake carbon dioxide by photoautotrophic cultivation of algae has been proposed to mitigate atmospheric carbon emissions. Multiple models to predict algal growth as a function of nutrients have been proposed, but few have delved into the complex dynamic reactions of algal growth as influenced
Elizabeth Flanagan, Caye Drapcho, Mary Katherine Watson   +2 more
wiley   +1 more source

Synthesis and Evaluation of Thiazolidinone-Isatin Hybrids for Selective Inhibition of Cancer-Related Carbonic Anhydrases. [PDF]

ACS Med Chem Lett
Onali A, Sanna E, Lupia A, Secci D, Atzeni G, Demuru L, Angeli A, Cottiglia F, Meleddu R, Emmolo R, Corona A, Maccioni E, Supuran CT, Distinto S.   +13 more
europepmc   +1 more source

Hypokalemic Periodic Paralysis in a Young Woman With Mast Cell Activation Syndrome: A Case Report of an Atypical Presentation Associated With an Ultra‐Rare CACNA1S Variant

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Hypokalemic periodic paralysis (hKPP) is a rare neuromuscular channelopathy characterized by transient episodes of muscle weakness or paralysis associated with low serum potassium levels. It has been most commonly linked to autosomal dominant mutations in ion channel genes, specifically CACNA1S and SCN4A, which impair skeletal muscle ...
Ali Moradi, Yasmin Aboutaleb, Saba Noreen, Abdullah Sahyouni, Hasin Sharma, Olugbenga Oyesanmi, Ian M. Kahane, Yizhi Lin, Hakan R. Toka   +8 more
wiley   +1 more source

Synergistic roles of aquaporin 5 and intra- and extracellular carbonic anhydrases in promoting CO₂ diffusion across the Xenopus oocyte plasma membrane. [PDF]

J Physiol
Wang DK, Moss FJ, Boron WF.
europepmc   +1 more source

Allergic Contact Dermatitis From Dorzolamide Without Cross‐Reactivity to Brinzolamide

Contact Dermatitis, Volume 95, Issue 1, Page 116-117, July 2026.
Elias Ghozli, Camille Leleu, Louis Arnould, Louise Collin, Evelyne Collet   +4 more
wiley   +1 more source