A topological selection of folding pathways from native states of knotted proteins [PDF]
Understanding the biological function of knots in proteins and their folding process is an open and challenging question in biology. Recent studies classify the topology and geometry of knotted proteins by analysing the distribution of a protein's planar projections using topological objects called knotoids.
arxiv
Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems
This review discusses dynamically responsive self‐assembling peptide‐based nano‐drug systems, including the stimulation response, strategy of biomimicry, subcellular internalization, and the applications of peptide nano‐drug materials, and concludes with a brief outlook of their challenges and opportunities in clinical translation.
Yuhan Wang+6 more
wiley +1 more source
Ferromagnetism of an all-carbon composite composed of a carbon nanowire nside a single-walled carbon nanotube [PDF]
Using the first-principles spin density functional approach, we have studied magnetism of a new type of all-carbon nanomaterials, i.e., the carbon nanowires inserted into the single-walled carbon nanotubes. It is found that if the 1D carbon nanowire density is not too higher, the ferromagnetic ground state will be more stable than the antiferromagnetic
arxiv +1 more source
Coral Carbonic Anhydrases: Regulation by Ocean Acidification
Global change is a major threat to the oceans, as it implies temperature increase and acidification. Ocean acidification (OA) involving decreasing pH and changes in seawater carbonate chemistry challenges the capacity of corals to form their skeletons ...
Didier Zoccola+5 more
doaj +1 more source
Biomedical applications of silk and its role for intervertebral disc repair
For years, researchers have been seeking a suitable biomaterial to repair and/or regenerate the intervertebral disc (IVD) and a promising candidate to fill this gap could be the application of silk. Therefore, this review aims to elaborate on the different origins from which silk is harvested, the characteristics of each silk type and how it can be ...
Andreas S. Croft+6 more
wiley +1 more source
Complementary experimental methods to obtain thermodynamic parameters of protein ligand systems [PDF]
In recent years, thermophoresis has emerged as a promising tool for quantifying biomolecular interactions. The underlying physical effect is still not understood. To gain deeper insight, we investigate whether non-equilibrium coefficients can be related to equilibrium properties.
arxiv
Ab initio studies of carbon dioxide affinity to carbon compounds and minerals [PDF]
We have performed quantum chemical computational studies to determine carbon dioxide affinity to carbon compounds and minerals, which could be present in shales. These studies shed light on the microscopic mechanisms of the possible carbon oxide sequestration processes. Our studies reveal that the carbon oxide can be adsorbed to various forms of carbon
arxiv +1 more source
Sucrose rinse modulates the salivary behavior of carbonic anhydrase VI and its buffering capacity: a longitudinal study in 4 to 6.5-year-old children [PDF]
Background Carbonic anhydrase VI (CA VI) is crucial in regulating oral pH and predicting susceptibility to dental caries. The hypothesis posits that caries activity may alter the CA VI function, diminishing its capacity to regulate pH effectively and ...
Thayse Rodrigues de Souza+5 more
doaj +2 more sources
Large presence of carbonic acid in CO$_2$-rich aqueous fluids under Earth's mantle conditions [PDF]
The chemistry of carbon in aqueous fluids at extreme pressure and temperature conditions is of great importance to Earth's deep carbon cycle, which substantially affects the carbon budget at Earth's surface and global climate change. At ambient conditions, the concentration of carbonic acid in water is negligible, so aqueous carbonic acid was simply ...
arxiv +1 more source
Visible‐light‐switchable azobenzenes: Molecular design, supramolecular systems, and applications
Abstract Photocontrol of functional molecules and supramolecular systems provides promising directions for the development of innovative materials and technologies. Reversible photoswitches that can isomerize among different states play a vital role in such photoresponsive systems. However, the commonly used UV light for triggering the isomerization of
Minghao Gao+3 more
wiley +1 more source