Results 91 to 100 of about 13,627 (214)

EvoMut: A computational framework for engineering oxidative stability in proteins

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Amino acid oxidation is a major cause of protein instability and loss of function in therapeutic and industrial settings. Although methionine, cysteine, tryptophan, tyrosine, histidine, lysine, and arginine residues are widely recognized as oxidation‐prone, only a subset of such residues is dominant functional hotspots, and not all are ...
Seyed Shahriar Arab, Chenlin Hsieh, Nathan E. Lewis   +2 more
wiley   +1 more source

Exclusive Hydroformylation of Terminal Olefins: A Phosphorus‐Free Ruthenium System for the Selective Functionalization of Complex Mixtures

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Development of a phosphorus‐free Ru/DBU catalyst enabling highly chemo‐ and regioselective hydroformylation of terminal olefins, sparing internal double bonds. Optimization of reaction parameters, ligand effects, and substrate scope including industrial feedstocks was realized.
Mohamed Niyaz Vellala Syed Ali, Ida Ziccarelli, Dilver Peña Fuentes, Christoph Kubis, Robert Franke, Ralf Jackstell, Matthias Beller   +6 more
wiley   +2 more sources

Organic and Inorganic Pollutants, Oxidative Stress Biomarkers, and Electrophoretic Protein Profiles in an Endangered Thresher Shark (Alopias vulpinus) From Southeastern Brazil: A Case Study

Environmental Toxicology, Volume 41, Issue 10, Page 833-848, October 2026.
ABSTRACT A comprehensive screening of different environmental contaminants (total metals, thermostable metal fractions associated with detoxification, and persistent organic pollutants) was conducted in an endangered common thresher shark (Alopias vulpinus ) individual incidentally captured in southeastern Brazil.
Sidney Fernandes Sales Junior, Amanda Pontes Lopes, Heloíse Martins de Souza, Regina Fonseca, Enrico Mendes Saggioro, Francielli Monteiro Casanova, Kamila Cezar Gramlich, Tatiana Dillenburg Saint'Pierre, Carlos German Massone, Renato Carreira, Rachel Ann Hauser‐Davis   +10 more
wiley   +1 more source

Effects of repeated exposure to ozonated water on hair fibre structure and integrity: Part I

International Journal of Cosmetic Science, Volume 48, Issue 5, Page 1077-1092, October 2026.
Repeated exposure to ozonated water caused cumulative oxidative changes in hair, altering structural integrity, thermal behaviour and mechanical properties. The findings reveal a distinct ozone‐induced damage profile that progresses beyond the cuticle, challenging claims of hair‐revitalizing benefits. Abstract Objective Ozone has recently been marketed
Pedro Augusto Laurindo Igreja Marrafa, Shamish Ganpule, Vanessa Castro‐Haly, Adriana Barrinha Fernandes, Ernesta Malinauskyte, Carlos Jose de Lima   +5 more
wiley   +1 more source

Oxidative Stress, Post‐Translational Modifications, and Type 1 Diabetes Pathogenesis

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Type 1 diabetes (T1D) is an organ‐specific autoimmune disease that destroys insulin‐producing beta‐cells. Insulin is a vital hormone for regulating glycemia that often undergoes post‐translational modifications during processing from pre‐proinsulin to biologically active insulin.
Colleen J. Winstead, Miki Hodel, Hubert M. Tse   +2 more
wiley   +1 more source

Beta Cell Stress to Epitope Diversification: Post‐Translationally Modified Antigens in Type 1 Diabetes

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Pancreatic beta cells are active participants in the loss of immune tolerance because their high secretory demand creates exceptional vulnerability to inflammatory exposure, endoplasmic reticulum (ER) stress, calcium dysregulation, and redox imbalance. These conditions can promote enzymatic and nonenzymatic changes in self‐proteins, generating
Megan L. Proffer, Saptarshi Roy, Jon D. Piganelli   +2 more
wiley   +1 more source

Integrated multitissue analysis reveals distinct oxidative stress responses during recovery from cold shock in the Amazonian fish Colossoma macropomum

Journal of Fish Biology, Volume 109, Issue 4, Page 2318-2331, October 2026.
Abstract Tambaqui (Colossoma macropomum) is a tropical fish widely cultivated in South America. The increasing demand for this species has heightened interest in its cultivation in subtropical regions with greater thermal variability, where cold shock may induce oxidative stress. This study evaluated the effects of cold shock and subsequent recovery on
Naiara Melo, Isaac Konig, Stefania Priscilla de Souza, Maria Fernanda Aquino Freitas, Daniella Aparecida de Jesus Paula, Ronald Kennedy Luz, Priscila Vieira Rosa, Luis David Solis Murgas   +7 more
wiley   +1 more source

A cross‐species post‐translational modification profiling of histones by LC‐MS/MS revealed conserved oxidative modifications in plants

New Phytologist, Volume 252, Issue 2, Page 538-545, October 2026.
Conservation of post‐translational modifications (PTMs) in histones across six plant species.
Sau‐Shan Cheng, Wai‐Ching Sin, Yuen‐Yi Chau, Hon‐Ming Lam   +3 more
wiley   +1 more source

Cobalt‐Catalyzed C(sp3)H Carbonylation Enabled by Mo(CO)6

European Journal of Organic Chemistry, Volume 29, Issue 36, 24 September 2026.
Cobalt‐catalyzed carbonylative C(sp3)H cyclization of aliphatic amides using Mo(CO)6 as a solid CO surrogate enables efficient access to substituted succinimides under operationally simple conditions. The carbonylation of unactivated C(sp3)H bonds represents an attractive strategy for the synthesis of valuable carbonyl‐containing compounds.
Emma Duro, Inés Alonso, Juan Carlos Carretero, Nuria Rodríguez, Javier Adrio   +4 more
wiley   +1 more source

Transition-metal catalyzed synthesis of Ketoprofen

Journal of the Brazilian Chemical Society, 2000
Transition metal-catalyzed reactions including carbonylations, hydrovinylations and hydrogenations have been applied in the synthesis of alpha-(3-benzoylphenyl)propanoic acid (Ketoprofen). 3-Vinylbenzophenone was obtained from 3-bromobenzophenone by a Pd-
Ramminger Carolina, Zim Danilo, Lando Vanusa R., Fassina Viviane, Monteiro Adriano L.   +4 more
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