Protein Carbonylation and Lipid Peroxidation in Hematological Malignancies [PDF]
Antioxidants, 2020 Among the different mechanisms involved in oxidative stress, protein carbonylation and lipid peroxidation are both important modifications associated with the pathogenesis of several diseases, including cancer.
Alba Rodríguez-García +5 more
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Protein Carbonylation as a Biomarker of Oxidative Stress and a Therapeutic Target in Neonatal Brain Damage [PDF]
Antioxidants, 2023 Oxidative stress (OS) constitutes a pivotal factor within the mechanisms underlying brain damage, for which the immature brain is particularly vulnerable.
José Martínez-Orgado +6 more
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Protein Carbonylation in Patients with Myelodysplastic Syndrome: An Opportunity for Deferasirox Therapy [PDF]
Antioxidants, 2019 Control of oxidative stress in the bone marrow (BM) is key for maintaining the interplay between self-renewal, proliferation, and differentiation of hematopoietic cells.
Alba Rodríguez-García +12 more
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Explainable Deep Multilevel Attention Learning for Predicting Protein Carbonylation Sites [PDF]
Advanced ScienceProtein carbonylation refers to the covalent modification of proteins through the attachment of carbonyl groups, which arise from oxidative stress. This modification is biologically significant, as it can elicit modifications in protein functionality ...
Jian Zhang +6 more
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Protein Carbonylation: Emerging Roles in Plant Redox Biology and Future Prospects [PDF]
Plants, 2021 Plants are sessile in nature and they perceive and react to environmental stresses such as abiotic and biotic factors. These induce a change in the cellular homeostasis of reactive oxygen species (ROS).
Adesola J. Tola +2 more
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Rules governing selective protein carbonylation. [PDF]
PLoS ONE, 2009 BACKGROUND:Carbonyl derivatives are mainly formed by direct metal-catalysed oxidation (MCO) attacks on the amino-acid side chains of proline, arginine, lysine and threonine residues.
Etienne Maisonneuve +6 more
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Protein carbonylation detection methods: A comparison [PDF]
Data in Brief, 2018 The data reported here are a comparison among four different methods for the detection of carbonylated proteins, a validated biomarker of oxidative stress.
Esra'a Alomari +5 more
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Reactive oxygen species-induced protein carbonylation promotes deterioration of physiological activity of wheat seeds. [PDF]
PLoS ONE, 2022 During the seed aging process, reactive oxygen species (ROS) can induce the carbonylation of proteins, which changes their functional properties and affects seed vigor.
Bang-Bang Li +4 more
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Proteome-wide analysis of hydrogen peroxide-induced protein carbonylation in Arabidopsis thaliana [PDF]
Frontiers in Plant Science, 2022 IntroductionProtein carbonylation is a non-enzymatic and irreversible post-translational modification that occurs naturally in living organisms under the direct or indirect effect of reactive oxygen species (ROS). In animals, signaling pathways involving
Georges Yannick Fangue-Yapseu +2 more
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Detection of Protein Carbonylation in Gingival Biopsies from Periodontitis Patients with or Without Diabetes Mellitus—A Pilot Study [PDF]
Dentistry JournalBackground: Protein carbonylation is an irreversible post-translational modification that is considered indicative of oxidative damage. Objective: The purpose of the study was to examine by an immunohistochemical method for the first time the extent and ...
Alexandra Efthymiou +5 more
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