Results 41 to 50 of about 3,609,148 (217)

Protein carbonylation, cellular dysfunction, and disease progression [PDF]

, 2006
Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein function, which is considered a widespread indicator of severe oxidative damage and disease-derived protein dysfunction.
Dalle Donne, I., Rossi, Ranieri, Milzani, A., Carini, M., Colombo, R., Aldini, G.   +5 more
core   +1 more source

Cross-talk between lipid and protein carbonylation in a dynamic cardiomyocyte model of mild nitroxidative stress

Redox Biology, 2017
Reactive oxygen and nitrogen species (ROS/RNS) play an important role in the regulation of cardiac function. Increase in ROS/RNS concentration results in lipid and protein oxidation and is often associated with onset and/or progression of many ...
Eva Griesser, Venukumar Vemula, Nora Raulien, Ulf Wagner, Sandra Reeg, Tilman Grune, Maria Fedorova   +6 more
doaj   +1 more source

AminoxyTMT: A novel multi-functional reagent for characterization of protein carbonylation

BioTechniques, 2016
Protein carbonylation is a common oxidative stress (OS)—driven post-translational modification (PTM). Proteome-wide carbonylation events can best be characterized using a combination of analytical approaches.
Somaieh Afiuni-Zadeh, John C. Rogers, Sergei I. Snovida, Ryan D. Bomgarden, Timothy J. Griffin   +4 more
doaj   +1 more source

Shotgun redox proteomics: identification and quantitation of carbonylated proteins in the UVB-resistant marine bacterium, Photobacterium angustum S14. [PDF]

PLoS ONE, 2013
UVB oxidizes proteins through the generation of reactive oxygen species. One consequence of UVB irradiation is carbonylation, the irreversible formation of a carbonyl group on proline, lysine, arginine or threonine residues.
Sabine Matallana-Surget, Ricardo Cavicchioli, Charles Fauconnier, Ruddy Wattiez, Baptiste Leroy, Fabien Joux, Mark J Raftery, Philippe Lebaron   +7 more
doaj   +1 more source

Oxidative Stress and Protein Carbonylation in Malaria

, 2017
This chapter focuses on the perturbed redox space found in malaria associated to pathogenicity, tolerance, drug action, and drug resistance, highlighting the physiopathological effects of its chemistry as regulator of metabolic and immune responses and ...
Amalia Diez, María Linares, Linares Gómez, María, Bautista Santa Cruz, José Manuel, Puyet Catalina, Antonio, Díez Martín, Amalia, José M. Bautista, Antonio Puyet   +7 more
core   +1 more source

A Proteome-Centric View of Ageing, including that of the Skin and Age-Related Diseases: Considerations of a Common Cause and Common Preventative and Curative Interventions

Clinical, Cosmetic and Investigational Dermatology, 2023
Isabelle Benoit,1 Elodie Burty-Valin,2 Miroslav Radman3,4 1Medical Relations, NAOS-ILS, Aix-en-Provence, France; 2Scientific Valorization, NAOS Les Laboratoires, Aix-en-Provence, France; 3Faculté de Médecine, INSERM U1001, Université R.-Descartes Paris-5,
Benoit I, Burty-Valin E, Radman M
doaj  

CarbonylDB: a curated data-resource of protein carbonylation sites. [PDF]

Bioinformatics, 2018
Motivation Oxidative stress and protein damage have been associated with over 200 human ailments including cancer, stroke, neuro-degenerative diseases and aging.
Rao RSP, Zhang N, Xu D, Møller IM.
europepmc   +2 more sources

Effect of Cyclic Heat Exposure on the Growth Performance and Metabolism of Broilers Fed Palm Kernel Meal

Animal Research and One Health, EarlyView.
The aim of our study is to evaluate the interaction between HS and the incorporation of PKM in broiler chicken diets, as well as its effect on growth performance and metabolism. Based on the results obtained, PKM supplementation failed to mitigate the adverse effects of heat stress in broiler chickens. ABSTRACT The aim of this study was to evaluate the
Ahmed Mijiyawa, Elham Ghashghaei, Okasha Hamada, Huimin Wang, Lijing Sun, Yendouhamtchié Nadiedjoa, Dan Wang, Zhengkai Yue, Clarice Maa Maa Temhoul, Maxwell Ansong Okai, Muhammad Faisal Riaz, Felix Kwame Amevor, Wéré Pitala, Hai Lin   +13 more
wiley   +1 more source

Reversal of Chronic Stress‐Induced Inflammaging by Bazi Bushen Formula Through AMPK‐Sirtuins Axis Activation and Myeloid Reset

Exploration, EarlyView.
Chronic stressors trigger systemic immune remodeling marked by myeloid expansion and lymphoid suppression, and this immune imbalance subsequently drives tissue pathology through proinflammatory signaling and senescence amplification, with the lung and kidney confirmed as the most vulnerable target organs.
Mengnan Li, Zheming Chen, Lu Wang, Zixuan Wang, Shixiong Zhang, Kunxu Niu, Xiaogang Shen, Xuan Lu, Runtao Zhang, Yuning Jiang, Yawen Li, Yi Dai, Xiyang Tang, Bin Hou, Min Shi, Xiaoya Wang, Zhifang Guo, Xingyu Xing, Ning Kang, Hongrong Li, Tianyu Kang, Evelyne Bischof, Yunlong Hou, Zhenhua Jia   +23 more
wiley   +1 more source

Engineered Trx2p industrial yeast strain protects glycolysis and fermentation proteins from oxidative carbonylation during biomass propagation

Microbial Cell Factories, 2012
Background In the yeast biomass production process, protein carbonylation has severe adverse effects since it diminishes biomass yield and profitability of industrial production plants.
Gómez-Pastor Rocío, Pérez-Torrado Roberto, Cabiscol Elisa, Ros Joaquim, Matallana Emilia   +4 more
doaj   +1 more source