Redox proteomics identification of oxidatively modified myocardial proteins in human heart failure: implications for protein function. [PDF]
PLoS ONE, 2012 Increased oxidative stress in a failing heart may contribute to the pathogenesis of heart failure (HF). The aim of this study was to identify the oxidised proteins in the myocardium of HF patients and analyse the consequences of oxidation on protein ...
Maura Brioschi +6 more
doaj +1 more source
Cell signaling promoting protein carbonylation does not cause sulfhydryl oxidation: implications to the mechanism of redox signaling [PDF]
, 2017 Reactive oxygen species (ROS) have been recognized as second messengers, however, targeting mechanisms for ROS in cell signaling have not been defined.
Almansour, Faisal +4 more
core +3 more sources
Protein Carbonylation as a Reliable Read-Out of Urban Pollution Damage/Protection of Hair Fibers
Cosmetics, 2022 (1) Background: Environmental factors, such as airborne pollutants and solar UV, induce oxidative damage to proteins and lipids on hair fibers, leading to decreased hair strength and shine, increased fiber porosity, brittleness, dryness, and stiffness ...
Andrea Cavagnino +3 more
doaj +1 more source
iCarPS: a computational tool for identifying protein carbonylation sites by novel encoded features
Bioinform., 2020 MOTIVATION Protein carbonylation is one of the most important oxidative stress-induced post-translational modifications (PTMs), which is generally characterized as stability, irreversibility and relative early formation.
Dan Zhang +6 more
semanticscholar +1 more source
Serotonin signaling through the 5-HT1B receptor and NADPH oxidase 1 in pulmonary arterial hypertension [PDF]
, 2017 Objective: Serotonin can induce human pulmonary artery smooth muscle cell (hPASMC) proliferation through reactive oxygen species (ROS), influencing the development of pulmonary arterial hypertension (PAH). We hypothesise that in PASMCs, serotonin induces
Harvey, Adam P. +5 more
core +2 more sources
Adaptations of Escherichia coli strains to oxidative stress are reflected in properties of their structural proteomes. [PDF]
, 2020 BACKGROUND:The reconstruction of metabolic networks and the three-dimensional coverage of protein structures have reached the genome-scale in the widely studied Escherichia coli K-12 MG1655 strain.
Catoiu, Edward +6 more
core +2 more sources
Bone Marrow Protein Oxidation in Response to Ionizing Radiation in C57BL/6J Mice
Proteomes, 2014 The bone marrow is one of the most radio-sensitive tissues. Accidental ionizing radiation exposure can damage mature blood cells and hematopoietic progenitor/stem cells, and mortality can result from hematopoietic insufficiency and infection.
Yong-Chul Kim +4 more
doaj +1 more source
BMC Bioinformatics, 2021 Background Carbonylation is a non-enzymatic irreversible protein post-translational modification, and refers to the side chain of amino acid residues being attacked by reactive oxygen species and finally converted into carbonyl products.
Yun Zuo +4 more
doaj +1 more source
Proteomic and carbonylation profile analysis of rat skeletal muscles following acute swimming exercise. [PDF]
PLoS ONE, 2013 Previous studies by us and other groups characterized protein expression variation following long-term moderate training, whereas the effects of single bursts of exercise are less known.
Francesca Magherini +9 more
doaj +1 more source
Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila [PDF]
, 2008 Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing hApoD are long-lived and protected against stress ...
Ahn +30 more
core +3 more sources