Relationship between Protein Oxidation Biomarkers and Uterine Health in Dairy Cows during the Postpartum Period [PDF]
, 2019 High neutrophil (PMN, Polymorphonuclear neutrophil) counts in the endometrium of cows affected by endometritis, suggests the involvement of oxidative stress (OS) among the causes of impaired fertility. Protein oxidation, in particular, advanced oxidation
Barberio, Antonio +7 more
core +2 more sources
Nature of Amide Carbonyl−Carbonyl Interactions in Proteins
Journal of the American Chemical Society, 2009 Noncovalent interactions define and modulate biomolecular structure, function, and dynamics. In many protein secondary structures, an intimate interaction exists between adjacent carbonyl groups of the main-chain amide bonds. As this short contact contributes to the energetics of protein conformational stability as well as protein-ligand interactions ...
Choudhary, Amit +3 more
openaire +2 more sources
Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness [PDF]
, 2014 Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen activated protein kinases (MAPK)
Bal, Elisa Dora +7 more
core +1 more source
Redox Biology, 2018 Aims: High levels of glucose and reactive carbonyl intermediates of its degradation pathway such as methylglyoxal (MG) may contribute to diabetic complications partly via increased generation of reactive oxygen species (ROS).
Cheryl S. Sultan +8 more
doaj +1 more source
Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment [PDF]
, 2014 There is an urgent need for rapid methods to develop vaccines in response to emerging viral pathogens. Whole inactivated virus (WIV) vaccines represent an ideal strategy for this purpose; however, a universal method for producing safe and immunogenic ...
Achilefu, Samuel +10 more
core +2 more sources
Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart [PDF]
, 2014 This is the final version. It was first published by Wiley in The Journal of Physiology at http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2014.275263/abstract.Hypoxic exposure is associated with impaired cardiac energetics in humans and altered ...
Andrew J. Murray +11 more
core +2 more sources
Redox Biology, 2017 Reactive oxygen and nitrogen species (ROS/RNS) play an important role in the regulation of cardiac function. Increase in ROS/RNS concentration results in lipid and protein oxidation and is often associated with onset and/or progression of many ...
Eva Griesser +6 more
doaj +1 more source
Downhill exercise alters immunoproteasome content in mouse skeletal muscle [PDF]
, 2017 Content of the immunoproteasome, the inducible form of the standard proteasome, increases in atrophic muscle suggesting it may be associated with skeletal muscle remodeling.
Baumann, Cory W. +3 more
core +1 more source
Cell Signaling by Protein Carbonylation and Decarbonylation [PDF]
Antioxidants & Redox Signaling, 2010 Reactive oxygen species (ROS) serve as mediators of signal transduction. However, mechanisms of how ROS influence the target molecules to elicit signaling event have not been defined. Our laboratory recently accumulated evidence for the role of protein carbonylation in the mechanism of ROS signaling.
Chi Ming, Wong +3 more
openaire +3 more sources
Shotgun redox proteomics: identification and quantitation of carbonylated proteins in the UVB-resistant marine bacterium, Photobacterium angustum S14. [PDF]
PLoS ONE, 2013 UVB oxidizes proteins through the generation of reactive oxygen species. One consequence of UVB irradiation is carbonylation, the irreversible formation of a carbonyl group on proline, lysine, arginine or threonine residues.
Sabine Matallana-Surget +7 more
doaj +1 more source