Results 71 to 80 of about 6,508,178 (232)

Oxidant-Mediated Protein Amino Acid Conversion

Antioxidants, 2019
Biological oxidation plays important roles in the pathogenesis of various diseases and aging. Carbonylation is one mode of protein oxidation. It has been reported that amino acids that are susceptible to carbonylation are arginine (Arg), proline (Pro ...
Yuichiro J. Suzuki
doaj   +1 more source

Nrf2-mediated neuroprotection response to recurrent hypoglycemia is insufficient to prevent cognitive impairment in a rodent model of type 1 diabetes [PDF]

, 2016
It remains uncertain whether recurrent nonsevere hypoglycemia (Hypo) results in long-term cognitive impairment in type 1 diabetes (T1D). This study tested the hypothesis that specifically in the T1D state, Hypo leads to cognitive impairment via a ...
Ashford, Michael L. J., Dinkova-Kostova, Albena T., Gallagher, Jennifer R., Hayes, John D., McCrimmon, Rory J., McNeilly, Alison D., Sharkey, John   +6 more
core   +2 more sources

Organic and Inorganic Pollutants, Oxidative Stress Biomarkers, and Electrophoretic Protein Profiles in an Endangered Thresher Shark (Alopias vulpinus) From Southeastern Brazil: A Case Study

Environmental Toxicology, EarlyView.
ABSTRACT A comprehensive screening of different environmental contaminants (total metals, thermostable metal fractions associated with detoxification, and persistent organic pollutants) was conducted in an endangered common thresher shark (Alopias vulpinus ) individual incidentally captured in southeastern Brazil.
Sidney Fernandes Sales Junior, Amanda Pontes Lopes, Heloíse Martins de Souza, Regina Fonseca, Enrico Mendes Saggioro, Francielli Monteiro Casanova, Kamila Cezar Gramlich, Tatiana Dillenburg Saint'Pierre, Carlos German Massone, Renato Carreira, Rachel Ann Hauser‐Davis   +10 more
wiley   +1 more source

Plasma protein carbonylation in chronic uremia

Journal of Nephrology, 2011
Carbonylation is an irreversible modification caused by the introduction into proteins of carbonyl derivatives (aldehydes and ketones), which can alter protein structure and function and lead to cellular dysfunction and tissue damage. Chronic uremia may be associated with an increased carbonyl overload ("carbonyl stress"), though carbonyl formation has
Pavone B, SIROLLI, Vittorio, Giardinelli A, BUCCI, SONIA, Forli' F, Di Cesare M, SACCHETTA, Paolo, DI PIETRO, NATALIA, PANDOLFI, Assunta, Urbani A, BONOMINI, Mario   +10 more
openaire   +3 more sources

Quantitation of protein carbonylation by dot blot [PDF]

Analytical Biochemistry, 2012
Protein carbonylation is the most commonly used measure of oxidative modification of proteins. It is frequently measured spectrophotometrically or immunochemically by derivatizing proteins with the classical carbonyl reagent, 2,4-dinitrophenylhydrazine.
Nancy B, Wehr, Rodney L, Levine
openaire   +2 more sources

Gamete Formation Resets the Aging Clock in Yeast [PDF]

, 2018
Gametogenesis is a process whereby a germ cell differentiates into haploid gametes. We found that, in budding yeast, replicatively aged cells remove age-induced cellular damage during gametogenesis.
Amon, Angelika B, Unal, Elcin
core   +1 more source

Assessment of Oxidative Stress, Vitellogenin, and Human Health Risks Derived From Nile Tilapia Exposed to Metals and Metalloids in Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves, Priscila M. O. Muniz Cunha, Shênia Patrícia Corrêa Novo, Lorena Oliveira Souza Soares, Tatiana Dillenburg Saint‐Pierre, Fábio Veríssimo Correia, André Luís de Sá Salomão, Rachel Ann Hauser‐Davis, Enrico Mendes Saggioro   +8 more
wiley   +1 more source

Identification and evaluation of the role of the manganese efflux protein in [PDF]

, 2010
Background Deinococcus radiodurans accumulates high levels of manganese ions, and this is believed to be correlated with the radiation resistance ability of this microorganism. However, the maintenance of manganese ion homeostasis in D.
Hongxing Sun, Guangzhi Xu, Hongdan Zhan, Huan Chen, Zongtao Sun, Bing Tian, Yuejin Hua   +6 more
core   +1 more source

A Lavandula angustifolia flower extract and dipeptide‐4 blend modulates oxidative, glycative, autophagic and circadian pathways in human skin models

International Journal of Cosmetic Science, EarlyView.
The blend enhanced antioxidation, anti‐glycation, autophagy and circadian regulation in cell and skin models. Key markers included mitochondrial ROS, γ‐H2AX, AGEs, ATP, melatonin, LC3 and SOD. Significant improvements were visualized via fluorescence and quantified with statistical markers.
Lina Wang, Yuxuan Wu, Huiping Hu, Yanan Li, Peiwen Sun   +4 more
wiley   +1 more source

Endocrine‐Nutritional Synergy Between Sex Inversion and Microencapsulated Bioactives Enhances Growth, Intestinal Development, and Oxidative Stability in Nile Tilapia Larvae

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study evaluated the combined effects of sex inversion and microencapsulated supplementation with organic acids and essential oils on growth performance, tissue morphology, gene expression, and oxidative status in Nile tilapia (Oreochromis niloticus) larvae.
Jaísa Casetta, Eliane Gasparino, Caroline Isabela da Silva, Simone Siemer, Gabriela Hernandes Cangianelli, Ricardo Souza Vasconcellos, Ricardo Pereira Ribeiro, Graciele Caroline Mari, Jaqueline Roesler, Juliana Sofientini, Diogo de Oliveira Marques, Stefania Claudino‐Silva   +11 more
wiley   +1 more source