Results 81 to 90 of about 3,609,148 (217)

Mitochondrial ATP synthase is a target for TNBS-induced protein carbonylation in XS-106 dendritic cells

, 2008
ROS are produced in dendritic cells (DCs) during antigen presentation in contact hypersensitivity (CHS). As a result, ROS cause a number of nonenzymatic protein modifications, including carbonylation, which is the most widely used marker of oxidative ...
이주희, 김수찬, 이민걸, 조영훈, 김동현   +4 more
core   +1 more source

Increased Adipose Protein Carbonylation in Human Obesity [PDF]

Obesity, 2011
Insulin resistance is associated with obesity but mechanisms controlling this relationship in humans are not fully understood. Studies in animal models suggest a linkage between adipose reactive oxygen species (ROS) and insulin resistance. ROS oxidize cellular lipids to produce a variety of lipid hydroperoxides that in turn generate reactive lipid ...
Brigitte I, Frohnert, Alan R, Sinaiko, Federico J, Serrot, Rocio E, Foncea, Antoinette, Moran, Sayeed, Ikramuddin, Umar, Choudry, David A, Bernlohr   +7 more
openaire   +2 more sources

Oxygen‐Redox Hub: ERFVII Bifunctional Switch Coordinates Flood Survival in Plants

Modern Agriculture, Volume 4, Issue 2, December 2026.
Floods threaten global food security by creating hypoxic conditions that disrupt plant metabolism. Under normal oxygen levels, plant cysteine oxidases (PCOs) target ERFVII transcription factors for degradation while keeping survival related genes repressed.
Muhammad Azhar Hussain, Chenjing Shang
wiley   +1 more source

Gold-Catalyzed Alkoxy-Carbonylation of Organohalides [PDF]

Herein, for the first time, we disclose the gold-catalyzed alkoxy-carbonylation of organohalides utilizing ligand-enabled Au(I)/Au(III) redox catalysis.
Vincent, Gandon, Asish, Bera, Nitin T., Patil, Vivek W., Bhoyare   +3 more
core   +2 more sources

From Prevention to Healthy Longevity: Evaluating the Multi‐Systemic Effects of Physical Activity and Lifestyle Behaviours in Women

Reproductive, Female and Child Health, Volume 5, Issue 4, December 2026.
ABSTRACT Purpose Despite spending more on healthcare than any other high‐income nation, the United States faces comparatively poor life expectancy outcomes, primarily due to non‐compliance with preventable and modifiable lifestyle behaviours. This review evaluates the multi‐systemic benefits of physical activity, exercise, diet, weight management and ...
Darah Dilmaghani, Mary Collins, Gloria A. Bachmann   +2 more
wiley   +1 more source

Key factors regulating protein carbonylation by α,Î2 unsaturated carbonyls : a structural study based on a retrospective meta-analysis

, 2017
Protein carbonylation represents one of the most important oxidative-based modifications involving nucleophilic amino acids and affecting protein folding and function.
Mantovani, Chiara, Pedretti, Alessandro, Giulio Vistoli, Vistoli, Giulio, Silvia Gervasoni, Alessandro Pedretti, Aldini, Giancarlo, Chiara Mantovani, Giancarlo Aldini, Gervasoni, Silvia   +9 more
core   +1 more source

Protein Oxidation in the Lungs of C57BL/6J Mice Following X-Irradiation

Proteomes, 2015
Damage to normal lung tissue is a limiting factor when ionizing radiation is used in clinical applications. In addition, radiation pneumonitis and fibrosis are a major cause of mortality following accidental radiation exposure in humans.
Michal Barshishat-Kupper, Elizabeth A. McCart, James G. Freedy, Ashlee J. Tipton, Vitaly Nagy, Sung-Yop Kim, Michael R. Landauer, Gregory P. Mueller, Regina M. Day   +8 more
doaj   +1 more source

The Boron–Neuron Connection: The Potential of Boron‐Containing Molecules for Treating Incurable Amyotrophic Lateral Sclerosis

ChemMedChem, Volume 21, Issue 21, 12 November 2026.
Can a single element help address the multifactorial nature of ALS? Boron‐containing compounds combine responsiveness to reactive oxygen species (ROS), neuroprotective activity, and favorable pharmacological properties, offering a distinctive framework for disease modification in a complex disease like ALS.
Nitesh Sanghai, Billy Vuong, Muhammad Shaharyar K. Afridi, Sasha Leggett, Hemin Roghzai, Geoffrey K. Tranmer   +5 more
wiley   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan, Rengasamy Balakrishnan, Manivasagam Muthukumaran Tamilarasan, Subasri Pandian   +3 more
wiley   +1 more source

Bidirectional Strategy Applied to the Synthesis of Bis(spiroketal)butenolides Using Bismuth(III) Triflate as Catalyst

ChemistrySelect, Volume 11, Issue 41, 3 November 2026.
The direct synthesis of new trispiro compounds possessing two spiroketalbutenolide subunits only unified by a single carbon atom has been achieved according a tandem bidirectional sequence from a bis(acetylenic) diol and different α‐ketoesters. The reaction catalyzed by bismuth salts delivered as main product (R*,s*,R*) trispiro derivatives which ...
Fabienne Fache, Léa Meusnier, Olivier Piva   +2 more
wiley   +1 more source