Results 81 to 90 of about 6,508,178 (232)

Results supporting the concept of the oxidant-mediated protein amino acid conversion, a naturally occurring protein engineering process, in human cells [version 2; referees: 2 approved, 1 not approved]

F1000Research, 2018
Reactive oxygen species (ROS) play an important role in the development of various pathological conditions as well as aging. ROS oxidize DNA, proteins, lipids, and small molecules. Carbonylation is one mode of protein oxidation that occurs in response to
Yuichiro J. Suzuki, Jian-Jiang Hao
doaj   +1 more source

Acute total body ionizing gamma radiation induces long-term adverse effects and immediate changes in cardiac protein oxidative carbonylation in the rat.

PLoS ONE, 2020
Radiation-induced heart disease presents a significant challenge in the event of an accidental radiation exposure as well as to cancer patients who receive acute doses of irradiation as part of radiation therapy.
Elliot Rosen, Dmitry Kryndushkin, Baikuntha Aryal, Yanira Gonzalez, Leena Chehab, Jennifer Dickey, V Ashutosh Rao   +6 more
doaj   +1 more source

Anti-oxidants in Parkinson's disease therapy: a critical point of view [PDF]

, 2016
Parkinson's disease (PD) is a degenerative neurological syndrome, which is characterized by the preferential death of dopaminergic (DAergic) neurons in the SubstantiaNigra.
Beltramini, Mariano, Bisaglia, Marco, Bubacco, Luigi, Filograna, Roberta   +3 more
core   +2 more sources

Locomotor muscle dysfunction and rehabilitative exercise training in fibrotic interstitial lung disease: Where are we at and where could we go?

Experimental Physiology, EarlyView.
Abstract Exercise limitation is a cardinal feature of fibrotic interstitial lung disease arising from pulmonary gas exchange, respiratory mechanical and cardio‐circulatory abnormalities. More recently, it has been recognized that impairment in locomotor muscle function (e.g., reduced muscle mass/strength or heightened fatigability) might also play a ...
Sarah Thivent, J. Alberto Neder, Anne‐Catherine Bernard, Marie Coudurier, Michel Guinot, Frédéric Hérengt, Samuel Verges, Mathieu Marillier   +7 more
wiley   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

Increased Adipose Protein Carbonylation in Human Obesity [PDF]

Obesity, 2011
Insulin resistance is associated with obesity but mechanisms controlling this relationship in humans are not fully understood. Studies in animal models suggest a linkage between adipose reactive oxygen species (ROS) and insulin resistance. ROS oxidize cellular lipids to produce a variety of lipid hydroperoxides that in turn generate reactive lipid ...
Brigitte I, Frohnert, Alan R, Sinaiko, Federico J, Serrot, Rocio E, Foncea, Antoinette, Moran, Sayeed, Ikramuddin, Umar, Choudry, David A, Bernlohr   +7 more
openaire   +2 more sources

Effects of Ramadan Fasting on Serum Amyloid A and Protein Carbonyl Group Levels in Patients With Cardiovascular Diseases [PDF]

Journal of Cardiovascular and Thoracic Research, 2015
Introduction: Serum amyloid-A (SAA) and protein carbonyl group are rigorously related with cardiovascular diseases (CVDs) as a sensitive marker of an acute inflammatory state and as an important index of oxidative stress, respectively.
Asadi Hami, Abolfathi Ali Akbar, Badalzadeh Reza, Majidinia Maryam, Yaghoubi Alireza, Asadi Maryam, Yousefi Bahman   +6 more
doaj   +1 more source

Effects of a Fish Oil Rich in Docosahexaenoic Acid on Cardiometabolic Risk Factors and Oxidative Stress in Healthy Rats

Marine Drugs, 2021
Omega-3 polyunsaturated fatty acids are associated with a lower risk of cardiometabolic diseases. However, docosahexaenoic acid (DHA) is easily oxidized, leading to cellular damage.
Bernat Miralles-Pérez, Lucía Méndez, Maria Rosa Nogués, Vanessa Sánchez-Martos, Àngels Fortuño-Mar, Sara Ramos-Romero, Mercè Hereu, Isabel Medina, Marta Romeu   +8 more
doaj   +1 more source

In vivo inhibition of the mitochondrial H+-ATP synthase in neurons promotes metabolic preconditioning [PDF]

, 2014
A key transducer in energy conservation and signaling cell death is the mitochondrial H+-ATP synthase. The expression of the ATPase inhibitory factor 1 (IF1) is a strategy used by cancer cells to inhibit the activity of the H+-ATP synthase to generate a ...
Cuezva, José M., Formentini, Laura, Lucas, José J., Martínez-Serrano, Alberto, Navarro, Carmen, Pereira, Marta P., Santacatterina, Fulvio, Sánchez-Cenizo, Laura   +7 more
core   +3 more sources

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem, Samuel G. Robichaud, Simon G. Lamarre, Graham R. Scott   +3 more
wiley   +1 more source