Results 101 to 110 of about 13,056 (198)

Protein carbonylation levels in WT and transgenic lines under oxidative stress.

, 2015
Protein carbonylation levels were detected with anti-DNP antibodies in WT and transgenic plant leaves under normal conditions or 100-μM MV treatments. Protein gel blot analysis of protein carbonylation following derivatization of protein carbonyls with ...
Shu-Mei Zhou (729145), Xiu-Dong Sun (729148), Wei Wang (17594), Han-Han Kang (729147), Xiang-Zhu Kong (729146)   +4 more
core   +1 more source

SOP: Determining Protein Carbonylation

, 2020
The formation of oxygen-derived free radicals has been frequently detected for several nanomaterials (NMs) in vitro and in vivo. Proteins are one of the major targets of oxygen free radicals and other reactive species leading to oxidative protein ...
Dr. Haase, Andrea (8335263), Dr. Giusti, Anna, Dr. Giusti, Anna (8335260), Dr. Haase, Andrea   +3 more
core   +1 more source

Aged Lewis rats exposed to low and moderate doses of rotenone are a good model for studying the process of protein aggregation and its effects upon central nervous system cell physiology

Arquivos de Neuro-Psiquiatria
Cell physiology is impaired before protein aggregation and this may be more relevant than inclusions themselves for neurodegeneration. The present study aimed to characterize an animal model to enable the analysis of the cell biology before and after ...
Michael F. Almeida, Carolliny M. Silva, Aline M. D’Unhao, Merari F. R. Ferrari   +3 more
doaj   +1 more source

Proteomic analysis and protein carbonylation profile in trained and untrained rat muscles. [PDF]

, 2012
Understanding the relationship between physical exercise, reactive oxygen species and skeletal muscle modification is important in order to better identify the benefits or the damages that appropriate or inappropriate exercise can induce.
Veicsteinas A, F. Esposito, Magherini, Francesca, Provvidenza Maria Abruzzo, A. Modesti, Modesti, Alessandra, Arsenio Veicsteinas, Marina Marini, Fiorillo, Claudia, Claudia Fiorillo, Bini L, Modesti A., M. Puglia, Esposito F, L. Bini, C. Fiorillo, Fabio Esposito, Gulisano M, M. Marini, Abruzzo PM, P. M. Abruzzo, Francesca Magherini, M. Gulisano, Marini M, ABRUZZO, PROVVIDENZA MARIA, BINI, LUCA, MARINI, MARINA, Fiorillo C, Michele Puglia, Luca Bini, Magherini F, Puglia M, Gamberi T, Tania Gamberi, Alessandra Modesti, F. Magherini, Gamberi, Tania, Gulisano, Massimo, Massimo Gulisano, A. Veicsteinas, T. Gamberi   +40 more
core   +1 more source

Protein carbonylation, protein aggregation and cell death in a murine model of multiple sclerosis

, 2013
Many studies have suggested that oxidative stress plays an important role in the pathophysiology of both multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE).
Dasgupta, Anushka
core   +1 more source

Proteomic Strategies for the Analysis of Carbonyl Groups on Proteins

Current Protein & Peptide Science, 2010
Oxidative stress is caused by an imbalance between formation and destruction of reactive oxygen species. Analysis of the reaction products of reactive oxygen species in biomolecules is an indirect way of determining the existence of oxidative stress.
Irazusta, Verónica Patricia, Moreno Cermeño, Armando, Cabiscol, Elisa, Tamarit, Jordi, Ros, Joaquim   +4 more
openaire   +3 more sources

Chemical Carbonylation of Arginine in Peptides and Proteins

Journal of the American Chemical Society
The chemoselective incorporation of arginine carbonylation post-translational modification (PTM) within proteins represents an underexplored frontier. This is largely due to the poor nucleophilicity and resistance to chemical oxidation of arginine.
Lyndsey Prosser, Benjamin Emenike, Pinki Sihag, Rajendra Shirke, Monika Raj   +4 more
openaire   +2 more sources

Protein Carbonylation and Glycation in Human Lenses

Collegium antropologicum, 2002
It has been observed protein carbonylation and glycation in the lens epithelial cell fractions of lenses in people with mature cataract. We used lenses of diabetic patients, weak and strong cigarette smokers and people who had senile cataract. The protein glycation is the highest in a diabetic senile cataract patients and the lowest in non-diabetic ...
Balog, Zlatko, Klepac, Ratomir, Šikić, Jakov, Jukić- Lešina, Tanja   +3 more
openaire   +3 more sources

Glucocorticoids Increase Protein Carbonylation and Mitochondrial Dysfunction

, 2013
Many major psychiatric illnesses have been associated with excessive and prolonged release of glucocorticoid stress hormones potentially leading to deleterious neuronal effects.
Tan, H, Young, A H; id_orcid, Tang, V M, Beasley, C, Wang, J-F   +4 more
core   +1 more source

Extensive protein carbonylation precedes acrolein-mediated cell death in mouse hepatocytes

, 2001
Allyl alcohol hepatotoxicity is mediated by an alcohol dehydrogenase-derived biotranformation product, acrolein. This highly reactive ,-unsaturated aldehyde readily alkylates model proteins in vitro, forming, among other products, Michael addition ...
Burcham, Philip Cyril, Fontaine, Frank, Fontaine, Frank R., Burcham, Philip C.   +3 more
core   +1 more source