Results 101 to 110 of about 6,508,178 (232)

Cytoprotective Effects of Organosulfur Compounds against Methimazole-Induced Toxicity in Isolated Rat Hepatocytes [PDF]

Advanced Pharmaceutical Bulletin, 2013
Purpose: Methimazole is a drug widely used in hyperthyroidism. However, life-threatening hepatotoxicity has been associated with its clinical use. No protective agent has been found to be effective against methimazole-induced hepatotoxicity yet.
Mohammad Ali Eghba, Hossein Babaei, Reza Heidari   +2 more
doaj   +1 more source

A breakthrough on Amanita phalloides poisoning: an effective antidotal effect by polymyxin B [PDF]

, 2015
Amanita phalloides is responsible for more than 90 % of mushroom-related fatalities, and no effective antidote is available. a-Amanitin, the main toxin of A. phalloides, inhibits RNA polymerase II (RNAP II), causing hepatic and kidney failure.
A Onufriev, A Zheleva, A Zheleva, Alexandra T. P. Carvalho, AP Zavascki, BD Beck, BK Wills, C Gao, CA Beelman, CN Broussard, CW Pinson, DA Bushnell, DA Case, Daniel F. A. R. Dourado, DJ Barbosa, DR Larson, E Kaya, Félix Carvalho, G Leclerc, G Vogel, GM Morris, I Dalle-Donne, I-M Chang, J Garcia, J Garcia, J Guhaniyogi, J He, J Ross, J Vetter, J Weiser, J Zhao, JB Mowry, JL Dores-Sousa, José Alberto Duarte, Juliana Garcia, KH Reuner, M Leist, M Mydlik, MA Koda-Kimble, Marcelo D. Arbo, Maria de Lourdes Bastos, MM Murr, P Poucheret, PA Kollman, Paula Baptista, PCK Cheung, Ricardo Jorge Dinis-Oliveira, Ricardo Silvestre, SM Schneider, SM Schneider, T Lawrence, T Wieland, T Wieland, TC Tong, Teresa Baltazar, V Fineschi, Vera Marisa Costa, XP Zhang, Y Yamaura, YF Zhao   +59 more
core   +1 more source

Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
This review deals with many aspects related to the study of phenolic compounds, starting with advances in extraction, detection, and quantification methods, going through bioavailability, bioactivity, and beneficial health properties, and discussing antioxidant and antimicrobial uses and mechanisms.
Marcela de Sá Barreto da Cunha, Cristina Maria Turim Santos Miguel, Emília Maria França Lima, Uelinton Manoel Pinto, Cláudia Vieira Prudêncio, Svetoslav Dimitrov Todorov   +5 more
wiley   +1 more source

A Review of Metal–Organic Framework (MOF) Based Active Food Packaging: Materials Selection, Cellulose Matrices Current Advances, Synthesis and Characterizations

Packaging Technology and Science, Volume 39, Issue 5, Page 533-572, May 2026.
Active packaging offers an effective approach to extending food shelf life. This review summarizes the past decade of progress in metal‐organic framework (MOF)‐based active food packaging, highlighting material selection, characterization, challenges, and future prospects.
Belladini Lovely, Young‐Teck Kim, Haibo Huang, Novitri Hastuti, Su Jung Hong   +4 more
wiley   +1 more source

Protein carbonylation is a mediator in larvicidal mechanisms of Tabernaemontana cymosa ethanolic extract

Journal of King Saud University - Science, 2019
Aedes aegypti mosquito is considered the most efficient vector for the spread of dengue, chikungunya, and zika viruses around the world and it is commonly controlled with synthetic insecticides.
E. Rodríguez-Cavallo, Javier Guarnizo-Méndez, Adriana Yépez-Terrill, Aury Cárdenas-Rivero, Fredyc Díaz-Castillo, D. Méndez-Cuadro   +5 more
semanticscholar   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos, Ana Margarida Araújo, Isabel M. P. L. V. O. Ferreira, Miguel A. Faria   +3 more
wiley   +1 more source

Protein Oxidation in the Lungs of C57BL/6J Mice Following X-Irradiation

Proteomes, 2015
Damage to normal lung tissue is a limiting factor when ionizing radiation is used in clinical applications. In addition, radiation pneumonitis and fibrosis are a major cause of mortality following accidental radiation exposure in humans.
Michal Barshishat-Kupper, Elizabeth A. McCart, James G. Freedy, Ashlee J. Tipton, Vitaly Nagy, Sung-Yop Kim, Michael R. Landauer, Gregory P. Mueller, Regina M. Day   +8 more
doaj   +1 more source

Proteomic evaluation of citrate-coated silver nanoparticles toxicity in Daphnia magna [PDF]

, 2014
Recent decades have seen a strong increase in the promise and uses of nanotechnology. This is correlated with their growing release in the environment and there is concern that nanomaterials may endanger ecosystems. Silver nanoparticles (AgNPs) have some
Carolan, Darragh, Doyle, Hugh, Rainville, Louis-Charles, Sheehan, David, Varela, Ana Coelho   +4 more
core   +1 more source

The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia, Michael Kapsalis, Michael Georgoulakis, Athanasios Panousis, Constantinos G. Neochoritis   +4 more
wiley   +1 more source

Histone Carbonylation Is a Redox-Regulated Epigenomic Mark That Accumulates with Obesity and Aging

Antioxidants, 2020
Oxidative stress is a hallmark of metabolic disease, though the mechanisms that define this link are not fully understood. Irreversible modification of proteins by reactive lipid aldehydes (protein carbonylation) is a major consequence of oxidative ...
Amy K. Hauck, Tong Zhou, Ambuj Upadhyay, Yuxiang Sun, Michael B. O’Connor, Yue Chen, David A. Bernlohr   +6 more
doaj   +1 more source