Results 11 to 20 of about 3,609,148 (217)

Protein carbonylation detection methods: A comparison [PDF]

Data in Brief, 2018
The data reported here are a comparison among four different methods for the detection of carbonylated proteins, a validated biomarker of oxidative stress.
Esra'a Alomari, Stefano Bruno, Luca Ronda, Gianluca Paredi, Stefano Bettati, Andrea Mozzarelli   +5 more
doaj   +8 more sources

Rules governing selective protein carbonylation. [PDF]

PLoS ONE, 2009
BACKGROUND:Carbonyl derivatives are mainly formed by direct metal-catalysed oxidation (MCO) attacks on the amino-acid side chains of proline, arginine, lysine and threonine residues.
Etienne Maisonneuve, Adrien Ducret, Pierre Khoueiry, Sabrina Lignon, Sonia Longhi, Emmanuel Talla, Sam Dukan   +6 more
doaj   +5 more sources

Protein Carbonylation in Plants

, 2017
This chapter provides an overview of the current knowledge on protein carbonylation in plants and its role in plant physiology. It starts with a brief outline of the turnover and production sites of reactive oxygen species (ROS) in plants and the causes of protein carbonylation.
Møller, Ian Max, Havelund, Jesper, Rogowska-Wrzesinska, Adelina   +2 more
core   +3 more sources

Protein carbonylation in human diseases

Trends in Molecular Medicine, 2003
Oxidative modifications of enzymes and structural proteins play a significant role in the aetiology and/or progression of several human diseases. Protein carbonyl content is the most general and well-used biomarker of severe oxidative protein damage. Human diseases associated with protein carbonylation include Alzheimer's disease, chronic lung disease,
DALLE DONNE I, GIUSTARINI D, COLOMBO R, ROSSI, RANIERI, AND MILZANI A.   +4 more
openaire   +4 more sources

Cell Signaling by Protein Carbonylation and Decarbonylation [PDF]

Antioxidants & Redox Signaling, 2010
Reactive oxygen species (ROS) serve as mediators of signal transduction. However, mechanisms of how ROS influence the target molecules to elicit signaling event have not been defined. Our laboratory recently accumulated evidence for the role of protein carbonylation in the mechanism of ROS signaling.
Chi Ming, Wong, Lucia, Marcocci, Lingling, Liu, Yuichiro J, Suzuki   +3 more
openaire   +4 more sources

Effects of chronic heat stress on Ca2+ homeostasis, apoptosis, and protein carbonylation profiles in the breast muscle of broilers [PDF]

Poultry Science
: Heat stress (HS) largely impairs the quality of broiler breast meat through protein oxidative modification. This study aimed to investigate the carbonylation pattern of Ca2+ channels and apoptotic proteins in the breast muscle of heat-stressed broilers.
Yingsen Liu, Zhen Liu, Tong Xing, Jiaolong Li, Lin Zhang, Liang Zhao, Feng Gao   +6 more
doaj   +2 more sources

Increased Carbonylation, Protein Aggregation and Apoptosis in the Spinal Cord of Mice with Experimental Autoimmune Encephalomyelitis

ASN Neuro, 2013
Previous work from our laboratory implicated protein carbonylation in the pathophysiology of both MS (multiple sclerosis) and its animal model EAE (experimental autoimmune encephalomyelitis).
Anushka Dasgupta, Jianzheng Zheng, Nora I. Perrone-Bizzozero, Oscar A. Bizzozero   +3 more
doaj   +2 more sources

Exploring oxysterols and protein carbonylation in cervicovaginal secretions as biomarkers for cervical cancer development [PDF]

Advances in Redox Research
Cervical cancer, a major global health issue and the fourth most common cancer among women, is strongly linked to Human Papillomavirus (HPV) infection.
Busra Kose, Serkan Erkanlı, Alper Koçak, Coskun Guzel, Theo Luider, Irundika H.K. Dias, Ahmet Tarik Baykal   +6 more
doaj   +2 more sources

Glucocorticoids Increase Protein Carbonylation and Mitochondrial Dysfunction

Hormone and Metabolic Research, 2013
Many major psychiatric illnesses have been associated with excessive and prolonged release of glucocorticoid stress hormones potentially leading to deleterious neuronal effects. Recent studies have suggested that oxidative stress is associated with psychiatric illnesses.
Tang, V M, Young, A H, Tan, H, Beasley, C, Wang, J-F   +4 more
openaire   +4 more sources

Iron Availability Influences Protein Carbonylation in Arabidopsis thaliana Plants. [PDF]

Int J Mol Sci, 2023
Protein carbonylation is an irreversible form of post-translational modification triggered by reactive oxygen species in animal and plant cells. It occurs either through the metal-catalyzed oxidation of Lys, Arg, Pro, and Thr side chains or the addition ...
Tola AJ, Missihoun TD.
europepmc   +2 more sources