Results 81 to 90 of about 13,627 (214)

Palladium-Catalyzed Selective Carbonylation Reactions of Ortho-Phenylene Dihalides with Bifunctional N,O-Nucleophiles

Molecules
Palladium-catalyzed carbonylation reactions of ortho-phenylene dihalides were studied using aminoethanols as heterobifunctional N,O-nucleophiles. The activity of aryl-iodide and -bromide as well as the chemoselective transformation of amine and hydroxyl ...
Fanni Bede, Attila Takács, László Kollár, Péter Pongrácz   +3 more
doaj   +1 more source

Vicinal Difunctionalization of Alkenes With Ketones and 1,2‐Bis(phenylsulfonyl)ethylene With One‐Electron Oxidation: A Three‐Component Route to Functionalized Vinyl Sulfones

ChemistryEurope, Volume 4, Issue 10, October 2026.
Three‐component coupling reactions of ketones, alkenes, and 1,2‐bis(phenylsulfonyl)ethylene (BPSE) proceed via one‐electron oxidation with K2S2O8 or Mn(OAc)3. Oxidative deprotonation of enols generates α‐keto radicals that undergo sequential alkene addition and BPSE trapping.
Lin‐Wei Pan, Shu‐Fan Wu, Yen‐Ku Wu, Hiroshi Matsubara, Ilhyong Ryu   +4 more
wiley   +1 more source

Application of Hosomi-Sakurai allylation reaction in total synthesis of biologically active natural products

Frontiers in Chemistry
The Hosomi–Sakurai allylation reaction has been widely applied in the total synthesis of biologically active natural products, especially in synthesising complex polycyclic compounds containing multi-stereogenic centres since its discovery in 1976.
Justice Akwensi, Robert T. Kumah, Dorcas Osei-Safo, Richard K. Amewu   +3 more
doaj   +1 more source

Amyloid‐Forming Amylin Secreted by the Pancreas Promotes Hypoxia‐Inducible Factor Activation and Mitochondrial Alterations in Liver and Heart During Type 2 Diabetes Pathogenesis

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Human amylin is secreted from the pancreas of HIP rats and is amyloidogenic, forming aggregates systemically. In comparison with age‐matched control (WT), hyperglycemic (UCD) and amylin knockout rats (AKO), HIP rats showed increased hypoxia‐inducible factors (HIF‐1/2) in heart and liver, alongside alterations in mitochondrial electron transfer system ...
Alice E. Knapton, Nirmal Verma, Deepak Kotiya, Alice P. Sowton, Benjamin D. Thackray, Lorenz M. W. Holzner, Paula M. Darwin, Sanda Despa, Florin Despa, Andrew J. Murray   +9 more
wiley   +1 more source

Integrated Metabolomic and Bioenergetic Profiling Reveals Axl as a Key Regulator of Macrophage Homeostasis

European Journal of Immunology, Volume 56, Issue 10, October 2026.
Axl deficiency disrupts peritoneal macrophage identity and function, impairing glycolysis, TCA metabolism, and mitochondrial respiration while weakening antioxidant defenses. This coordinated metabolic and redox collapse extends systemically, highlighting Axl as a key regulator of immunometabolic homeostasis.
Jesuino R M Ferreira, Thais S Rigoni, Monique S Leandro, Kamila Guimarães‐Pinto, Letícia R Ramos, André L A Costa, Clara F Carvalho, Caroline F Martiniuc, Isadora A Oliveira, Carolina Maia, Júlia Moratelli, Jefferson A Leite, Verônica S Pinto, Adriane Todeschini, Antônio Galina, Alessandra A Filardy   +15 more
wiley   +1 more source

Harnessing Terminalia arjuna in Next Generation Phytomedicine: Cutting Edge Nutraceutical Trends Shaping Food and Health

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee, Fahika Nazeerulla, Manash Kumar Paul, Sujit Kumar Bhutia, Deblina Basu, Subhadip Mukhopadhyay   +5 more
wiley   +1 more source

Synthesis and Structural Characterisation of [Ir4(CO)8(CH3)(m4-h3-Ph2PCCPh)(m-PPh2)] and of the Carbonylation Product [Ir4(CO)8{C(O)CH3}(m4-h3-Ph2PCCPh)(m-PPh2)]; First Evidence for the Formation of a CO Cluster Adduct before CO Insertion

Journal of the Brazilian Chemical Society, 1999
Deprotonation of [(mu-H)Ir4(CO)10(mu-PPh2)], 1, gives [Ir4(CO)10(mu-PPh2)]- that reacts with Ph2PCCPh and CH3I to afford [Ir4(CO)8(CH3)(mu4-eta³-Ph2PCCPh)(mu-PPh2)], 2 (34%), besides [Ir4(CO)9(mu3-eta³-Ph2PC(H)CPh)(mu-PPh2)] and [(mu-H)Ir4(CO)9(Ph2PCºCPh)
Braga Dario, Fujiwara Fred Y., Grepioni Fabrizia, Pereira Regina M.S., Vargas Maria D.   +4 more
doaj  

Chemotherapy‐Induced Skeletal Muscle Dysfunction and Cognitive Impairment: A Muscle‐Brain Mechanistic Framework With Implications for Exercise Oncology

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Chemotherapy commonly induces skeletal muscle dysfunction and cognitive impairment, complications that reduce treatment tolerance and quality of life. Skeletal muscle mass frequently declines during chemotherapy, with cohort studies reporting losses of 3%–10% across treatment courses, while chemotherapy‐induced cognitive impairment affects up ...
SoYoung Ahn, Jin‐Soo Kim, Daniel A. Galvao, Dennis R. Taaffe, Dong Hyun Yoon, Carolyn McIntyre, Christelle Schofield, Yoon Jung Chang, Jihee Min, Wook Song, Robert U. Newton   +10 more
wiley   +1 more source

Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies

MedComm, Volume 7, Issue 10, October 2026.
Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng, Qi Qin, Fang Wang, Kaiyuan Zhang, Zhihua Li, Junlei Chang, Min Yu, Fuyou Guo   +7 more
wiley   +1 more source

Nanopriming and Nanocoating as a Next‐Generation Seed Treatment for Enhanced Plant Growth and Pathogen Resistance

Plant-Environment Interactions, Volume 7, Issue 5, October 2026.
ABSTRACT In pursuit of sustainable agriculture, current strategies continue to explore environmentally friendly inputs that promote plant development. Seed treatment is an ancient practice used to break seed dormancy and hasten germination. Although traditional seed treatments yield positive outcomes, the methods adopted raise concerns about the ...
Okainemen Godfrey Oribhabor, Damian C. Onwudiwe, Vanessa Nessner Kavamura, Jing Ge, Olubukola Oluranti Babalola   +4 more
wiley   +1 more source