Results 131 to 140 of about 27,172,362 (207)

Hepatic carboxylesterase 1 is induced by glucose and regulates postprandial glucose levels. [PDF]

PLoS One, 2014
Xu J, Yin L, Xu Y, Li Y, Zalzala M, Cheng G, Zhang Y.   +6 more
europepmc   +1 more source

Cold-adapted carboxylesterases from Alcanivoracaceae active with a wide range of synthetic polyesters. [PDF]

Appl Microbiol Biotechnol
Ma H, Khusnutdinova AN, Chernikova TN, Ferrer M, Yakunin AF, Golyshina OV, Golyshin PN.   +6 more
europepmc   +1 more source

CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril. [PDF]

Eur J Clin Pharmacol, 2016
Zhu HJ, Langaee TY, Gong Y, Wang X, Pepine CJ, Cooper-DeHoff RM, Johnson JA, Markowitz JS.   +7 more
europepmc   +1 more source

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin-induced Intestinal Injury by Production of Carboxylesterase EstB. [PDF]

Adv Sci (Weinh)
Zhao Z, Li Q, Bai X, Zhai E, Dai W, Qian Y, Zhang T, Huang Z, Huang Z, Meng F, Chen J, Zuo T, Cai S, Zhao R.   +13 more
europepmc   +1 more source

Kinetic analysis suggests that malathion at low environmental exposures is not toxic to humans. [PDF]

PLoS One
Schopfer LM, Tacal O, Masson P, Lockridge O.   +3 more
europepmc   +1 more source

Delayed emergence with remimazolam after laparoscopic subsegmental hepatectomy including the intermittent pringle maneuver in a patient with preserved liver function. [PDF]

JA Clin Rep
Miyazaki R, Sekiya S, Okano H, Goto S, Okamoto H.   +4 more
europepmc   +1 more source

Transcriptome and Functional Analyses Revealed the Carboxylesterase Genes Involved in Pyrethroid Resistance in <i>Anopheles sinensis</i> (Diptera: Culicidae). [PDF]

Insects
Wei Y, Gu X, Si F, Chen X, Qiao L, Yan H, Chen B.   +6 more
europepmc   +1 more source

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Inhibition of carboxylesterase-1 alters clopidogrel metabolism and disposition

Xenobiotica, 2020
Clopidogrel is widely prescribed in patients with cardiovascular disease. Most research has focused on the role of hepatic CYP450 metabolism as the primary source of response variability despite 85–90% of clopidogrel being hydrolyzed by human ...
S. Laizure, Zhe-yi Hu, P. Potter, R. Parker   +3 more
semanticscholar   +3 more sources

Is genetic variability in carboxylesterase-1 and carboxylesterase-2 drug metabolism an important component of personalized medicine?

Xenobiotica, 2020
The carboxylesterase drug hydrolysis pathway has been used extensively to improve the oral availability of drugs under the assumption that the high capacity and low substrate specificity of hydrolytic enzymes would ensure rapid, complete, and consistent ...
S. Laizure, Robert B. Parker
semanticscholar   +3 more sources