Results 151 to 160 of about 15,347 (200)

Silencing carboxylesterase 1 in human THP-1 macrophages perturbs genes regulated by PPARγ/RXR and RAR/RXR: down-regulation of CYP27A1-LXRα signaling. [PDF]

Biochem J, 2018
Mangum LC, Hou X, Borazjani A, Lee JH, Ross MK, Crow JA.   +5 more
europepmc   +1 more source

Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension.

Am J Physiol Lung Cell Mol Physiol, 2017
Orcholski ME, Khurshudyan A, Shamskhou EA, Yuan K, Chen IY, Kodani SD, Morisseau C, Hammock BD, Hong EM, Alexandrova L, Alastalo TP, Berry G, Zamanian RT, de Jesus Perez VA.   +13 more
europepmc   +1 more source

Biochemical, molecular, and in silico insights into the effects of cyphenothrin on Culex quinquefasciatus mosquitoes. [PDF]

Parasit Vectors
Saha A, Das S, Das P, Ghosh S, Tamang A, Thakur S, Saha D.   +6 more
europepmc   +1 more source

Screening of ester-forming and hydrolyzing enzymes linked to pheromone production in Ips typographus (Linnaeus, 1758). [PDF]

BMC Genomics
Strádal J, Ramakrishnan R, Lukšan O, Tupec M, Synek J, Macháček S, Pichová I, Jirošová A.   +7 more
europepmc   +1 more source

Integrated transcriptomic and variant analysis reveals molecular mechanisms of pyrethroid resistance in a genetically homogenized Cas9 strain of Aedes aegypti. [PDF]

Arch Toxicol
Brown D, Houck R, Liu N.
europepmc   +1 more source

Cold-adapted carboxylesterases from Alcanivoracaceae active with a wide range of synthetic polyesters. [PDF]

Appl Microbiol Biotechnol
Ma H, Khusnutdinova AN, Chernikova TN, Ferrer M, Yakunin AF, Golyshina OV, Golyshin PN.   +6 more
europepmc   +1 more source

Integrated genomic and transcriptomic analysis reveals candidate genes underlying herbicide resistance in Sorghum. [PDF]

BMC Plant Biol
Xing Z, Cheng Z, Yang X, Hu L, Wang K, Wang Y, Hu D, Wang YH, Du J, Wang L, Li J.   +10 more
europepmc   +1 more source

Molecular cloning, purification and biochemical characterization of a novel pyrethroid-hydrolyzing carboxylesterase gene from Ochrobactrum anthropi YZ-1

Journal of Hazardous Materials, 2012
Strain YZ-1 was isolated from activated sludge and identified as Ochrobactrum anthropi. This strain was capable of degrading pyrethroids pesticides, suggesting the presence of degrading enzymes. In the present study, a novel esterase gene pytZ was cloned
Yi Zhai, Jinlong Song
exaly   +2 more sources

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Nomenclature for alleles of the human carboxylesterase 1 gene

Pharmacogenetics and Genomics, 2017
The carboxylesterase 1 gene (CES1) in humans encodes a hydrolase, which is implicated in the metabolism of several commonly used drugs 1. This gene is located on chromosome 16 with a highly homologous pseudogene, CES1P1, in its proximity. A duplicated segment of CES1 replaces most of CES1P1 in some individuals, thus leading to the formation of a hybrid
Rasmussen, Henrik Berg, Madsen, Majbritt B., Hansen, Peter R., Bjerre, Ditte, Ferrero, Laura, Linnet, Kristian, Thomsen, Ragnar, Jürgens, Gesche, Dalhoff, Kim Peder, Stage, Claus, Stefansson, Hreinn, Hankemeier, Thomas, Kaddurah-Daouk, Rima, Brunak, Søren, Taboureau, Olivier, Nzabonimpa, Grace Shema, Jeppesen, Pia, Kaalund-Jørgensen, Kristine, Kristensen, Karl Emil, Pagsberg, Anne Katrine, Plessen, Kerstin Jessica, Hansen, Poul Erik; id_orcid 0000-0003-4751-9910, Werge, Thomas, Dyrborg, Jørgen, Lauritzen, Maj Britt, Hughes, Tim, Lyauk, Yassine Kamal   +26 more
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Carboxylesterase 1 as a Determinant of Clopidogrel Metabolism and Activation

The Journal of Pharmacology and Experimental Therapeutics, 2013
Clopidogrel pharmacotherapy is associated with substantial interindividual variability in clinical response, which can translate into an increased risk of adverse outcomes. Clopidogrel, a recognized substrate of hepatic carboxylesterase 1 (CES1), undergoes extensive hydrolytic metabolism in the liver.
Hao-Jie, Zhu, Xinwen, Wang, Brian E, Gawronski, Bryan J, Brinda, Dominick J, Angiolillo, John S, Markowitz   +5 more
openaire   +2 more sources