Indole-3-Carboxylic Acid Enhanced Anti-cancer Potency of Doxorubicin via Induction of Cellular Senescence in Colorectal Cells [PDF]
Background: Colorectal cancer (CRC) is the most common gastrointestinal malignancy. Doxorubicin (DOX) is a widely utilized chemotherapy drug, but its efficacy is limited due to dose-dependent toxicity.
Yao Zhou+4 more
doaj +1 more source
Enabling Heterogeneous Catalysis to Achieve Carbon Neutrality: Directional Catalytic Conversion of CO$_2$ into Carboxylic Acids [PDF]
The increase in anthropogenic carbon dioxide (CO$_2$) emissions has exacerbated the deterioration of the global environment, which should be controlled to achieve carbon neutrality. Central to the core goal of achieving carbon neutrality is the utilization of CO$_2$ under economic and sustainable conditions.
arxiv
Bromopyrrole alkaloids from the caribbean sponge Agelas cerebrum
Bioguided fractionation of Agelas cerebrum crude extract resulted in isolation of four bromopyrrole and four bromopyrrole aminoimidazole alkaloids, identified as 5-bromopyrrole-2-carboxylic acid (1), 4-bromopyrrole-2-carboxylic acid (2), 3,4-bromopyrrole-
Erik L. Regalado+4 more
doaj +1 more source
Ringed spherulitic and undulated textures in the nematic phase of a mixture of trans-4-hexylcyclohexanecarboxylic and benzoic acids [PDF]
We present a polarising optical microscopy study of a liquid-crystal mixture of trans-4-hexylcyclohexanecarboxylic acid (C6) and benzoic acid. Both materials have carboxylic groups that can form dimers through hydrogen bonding. The mixture is nematic and room temperature and has the clearing point at 88 Celsius.
arxiv +1 more source
Reported is an achiral Cpx RhIII /chiral carboxylic acid catalyzed asymmetric C-H alkylation of diarylmethanamines with a diazomalonate, followed by cyclization and decarboxylation to afford 1,4-dihydroisoquinolin-3(2H)-one. Secondary alkylamines as well
Luqing Lin+5 more
semanticscholar +1 more source
[1,4]Diazepino[2,3-h]quinolone carboxylic acid 3 and its benzo-homolog tetrahydroquino[7,8-b]benzodiazepine-3-carboxylic acid 5 were prepared via PPAcatalyzed thermal lactamization of the respective 8-amino-7-substituted-1,4-dihydroquinoline-3-carboxylic
Yusuf M. Al-Hiari+2 more
doaj +1 more source
5,6-dihydroxyindole-2-carboxylic acid (DHICA): a First Principles Density-Functional Study [PDF]
We report first principles density functional calculations for 5,6-dihydroxyindole-2-carboxylic acid (DHICA) and several reduced forms. DHICA and 5,6-dihydroxyindole (DHI) are believed to be the basic building blocks of the eumelanins. Our results show that carboxylation has a significant effect on the physical properties of the molecules.
arxiv +1 more source
Diamondoids are not forever: microbial biotransformation of diamondoid carboxylic acids
Summary Oil sands process‐affected waters (OSPW) contain persistent, toxic naphthenic acids (NAs), including the abundant yet little‐studied diamondoid carboxylic acids.
Benjamin D. Folwell+2 more
doaj +1 more source
Valorization of Lignin by Partial Wet Oxidation Using Sustainable Heteropoly Acid Catalysts
The production of carboxylic acids by partial wet oxidation of alkali lignin at elevated temperatures and pressures was studied experimentally. Two different heteropoly acids, phosphotungstic acid (H3PW12O40) and phosphomolybdic acid (H3PMo12O40), were ...
Abayneh Getachew Demesa+3 more
doaj +1 more source
Nonlinear optical properties of mono-functional 1,2-dihydro-1,2-methanofullerene[60]-61-carboxylic acid /polymer composites [PDF]
By using nanosecond laser pulses at 532-nm wavelength, we have studied the nonlinear optical properties of composites which consist of mono-functional 1,2-dihydro-1,2-methanofullerene[60]-61-carboxylic acid (FCA) and poly(styrene-co-4-vinylpyridine).
arxiv +1 more source