Results 41 to 50 of about 5,170,686 (370)
Deoxygenative trifluoromethylthiolation of carboxylic acids
A deoxygenative trifluoromethylthiolation method produces trifluoromethyl thioesters from readily available carboxylic acids.
Runze Mao+3 more
openaire +5 more sources
Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis
Carboxylic acid reductase (CAR) catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes. The enzyme is related to the non-ribosomal peptide synthetases, consisting of an adenylation domain fused via a peptidyl ...
D. Gahloth+9 more
semanticscholar +1 more source
Propelled by enormous increase in demand for fuel sources, Canadian oil sands are becoming increasingly important as a fuel source due to their abundance and upgrading capability.
Rija Ansari, Deepak M. Kirpalani
doaj
Crystal structure of zymonic acid and a redetermination of its precursor, pyruvic acid
The structure of zymonic acid (systematic name: 4-hydroxy-2-methyl-5-oxo-2,5-dihydrofuran-2-carboxylic acid), C6H6O5, which had previously eluded crystallographic determination, is presented here for the first time.
Dominik Heger+3 more
doaj +1 more source
Bioinspired manganese and iron complexes bearing nonporphyrinic tetradentate N4 ligands are highly efficient catalysts in asymmetric oxidation reactions by hydrogen peroxide (H2O2), in which carboxylic acid is employed as an essential additive to improve
Junyi Du+6 more
semanticscholar +1 more source
Recent Advances in the Synthesis of Carboxylic Acid Esters
In this chapter, recent advances in the synthesis of carboxylic acid esters are summarized based on the utilization of carboxylic acids as electrophiles or nucleophiles in reactions.
Kouichi Matsumoto, Rina Yanagi, Y. Oe
semanticscholar +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Crystal structure of [1,1′:3′,1′′-terphenyl]-2′,3,3′′-tricarboxylic acid
The asymmetric unit of the title compound, C21H14O6, comprises two symmetrically independent molecules that form a locally centrosymmetric hydrogen-bonded dimer, with the planes of the corresponding carboxylic acid groups rotated by 15.8 (1) and 17.5 (1)°
Daniel A. Decato, Orion B. Berryman
doaj +1 more source
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Total lineshape analysis of α-tetrahydrofuroic acid $^{1}$H NMR spectra [PDF]
The 1H NMR spectra of L-proline oxygen analogous, alpha-tetrahydrofuroic acid, 7-spins nonsymmetric spin system with strongly pronounced non-first order effects were analyzed by ANATOLIA total lineshape fitting. A close agreement of theoretical and experimental spectra (with R-Factor values bellow 5%) was achieved and accurate values of coupling ...
arxiv